The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Effect of creatine supplementation on skeletal muscle of mdx mice
Abstract
Dystrophic mice (mdx) and their controls (C57/Bl10) were fed for 1 month with a diet with or without creatine (Cr) enrichment. Cr supplementation reduced mass (by 19%, P < 0.01) and mean fiber surface (by 25%, P < 0.05) of fast‐twitch mdx muscles. In both strains, tetanic tension increased slightly (9.2%) without reaching statistical significance (P = 0.08), and relaxation time increased by 16% (P < 0.001). However, Cr had no protective effect on the other hallmarks of dystrophy such as susceptibility to eccentric contractions; large numbers of centrally nucleated fibers in tibialis anterior; and elevated total calcium content, which increased by 85% (P = 0.008) in gastrocnemius mdx muscles. In conclusion, Cr may be a positive intervention for improving function of dystrophic muscle. Muscle Nerve 29: 687–692, 2004
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“Pre-clinical studies have shown pathological and functional benefits from CrM supplementation in murine models of DMD [196–199], and also in a murine model of fascio-scapulo-humeral dystrophy (FSHD) [200].”
From Creatine monohydrate supplementation for older adults and clinical populations (2025) · cites this paper as [198]
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Beneficial effects of creatine supplementation in dystrophic patients
Louis, M., Lebacq, J., Poortmans, J. R., Belpaire‐Dethiou, M., Devogelaer, J., Van Hecke, P., Goubel, F., & Francaux, M. (2003) · Muscle & Nerve · doi:10.1002/mus.10355 · Cited by 130
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Cited by
Clinical Use of Creatine in Neuromuscular and Neurometabolic Disorders
Tarnopolsky, M. A. (2007) · Subcellular Biochemistry · doi:10.1007/978-1-4020-6486-9_10 · Cited by 67
Creatine monohydrate supplementation for older adults and clinical populations
Candow, D. G., Ostojic, S. M., Chilibeck, P. D., Longobardi, I., Gualano, B., Tarnopolsky, M. A., Wallimann, T., Moriarty, T., Kreider, R. B., Forbes, S. C., et al. (2025) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2025.2534130 · Cited by 43
Insights into muscle atrophy and recovery pathway based on genetic models
Stein, T. P., & Bolster, D. R. (2006) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/01.mco.0000232899.51544.69 · Cited by 12
Metadata
- Authors
- Louis, M., Raymackers, J. M., Debaix, H., Lebacq, J., & Francaux, M.
- Venue
- Muscle & Nerve
- Publisher
- Wiley
- Published
- 2004-03-11
- Volume
- 29
- Issue
- 5
- Pages
- 687-692
- ISSN
- 0148-639X
- 1097-4598
- Cited by
- 19
- References
- 1
- Language
- en
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
