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Adiposity Without Obesity: Associations with Osteoporosis, Sarcopenia, and Falls in the Healthy Ageing Initiative Cohort Study
Abstract
Objective: Obesity is commonly defined by BMI rather than adiposity, which may have differential effects on musculoskeletal health. Musculoskeletal outcomes were compared in older adults with normal adiposity and normal BMI (NA‐NBMI), those with high adiposity but normal BMI (HA‐NBMI), and those with high adiposity and high BMI (HA‐HBMI). Methods: In 3,411 70‐year‐olds, obesity was defined as BMI ≥ 30 kg/m 2 and adiposity as body fat percentage ≥ 25% (men) or ≥ 35% (women) from dual‐energy x‐ray absorptiometry. Bone parameters were measured by dual‐energy x‐ray absorptiometry and peripheral quantitative computed tomography. Sarcopenia was defined as low handgrip strength with or without low appendicular lean mass. Falls were self‐reported 6 and 12 months later. Results: Prevalence of NA‐NBMI, HA‐NBMI, and HA‐HBMI was 14.2%, 68.1%, and 17.7%, respectively. Compared with HA‐HBMI, HA‐NBMI had increased likelihood for sarcopenia (adjusted odds ratio: 3.99; 95% CI: 1.41‐11.32) and osteoporosis (2.91; 95% CI: 2.35‐3.61) but similar likelihood of falls (P > 0.05). HA‐NBMI had lower values for bone geometry parameters, as well as grip strength, than both NA‐NBMI and HA‐HBMI (all P < 0.05). Conclusions: High adiposity without high BMI is more common than BMI‐defined obesity in older Swedish adults but does not provide similar protection from osteoporosis and sarcopenia.
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“Although the prevalence of low muscle mass in the present study (e.g., 16%–20% in older non-athletic controls) may be deemed as lower than observed in cohort studies [e.g., ∼41% (18)], this may be due to individuals that are generally interested in health and well-being volunteering for our studies.”
From Body composition in male lifelong trained strength, sprint and endurance athletes and healthy age-matched controls (2023) · cites this paper as [18]
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Cited by
Walker, S., von Bonsdorff, M., Cheng, S., Häkkinen, K., Bondarev, D., Heinonen, A., & Korhonen, M. T. (2023) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2023.1295906 · Cited by 29
Metadata
- Authors
- Scott, D., Johansson, J., Ebeling, P. R., Nordstrom, P., & Nordstrom, A.
- Affiliations
- Institute for Physical Activity and Nutrition School of Exercise and Nutrition Sciences Deakin University Geelong Victoria Australia
- Department of Public Health and Clinical Medicine Section of Sustainable Health Umeå University Umeå Sweden
- Department of Medicine School of Clinical Sciences at Monash Health Monash University Clayton Victoria Australia
- Department of Community Medicine and Rehabilitation Geriatric Medicine Umeå University Umeå Sweden
- ORCID
- Scott, David
- Venue
- Obesity
- Publisher
- Wiley
- Published
- 2020-10-03
- Volume
- 28
- Issue
- 11
- Pages
- 2232-2241
- ISSN
- 1930-7381
- 1930-739X
- Cited by
- 18
- References
- 7
- Language
- en
- Funders
- Forskningsrådet om Hälsa, Arbetsliv och Välfärd (2011‐2976)
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- Scott, D., Johansson, J., Ebeling, P. R., Nordstrom, P., & Nordstrom, A. (2020). Adiposity Without Obesity: Associations with Osteoporosis, Sarcopenia, and Falls in the Healthy Ageing Initiative Cohort Study. Obesity. https://doi.org/10.1002/oby.22984
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