The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Methods for evaluation of medication adherence and persistence using automated databases
Abstract
Purpose: Our aim was to perform a systematic review of the methods currently being used to assess adherence and persistence in pharmacoepidemiological and pharmacoeconomic studies using automated databases. Methods: A MEDLINE search of English language literature was performed to identify studies published between January 1, 1980 and March 31, 2004 that evaluated adherence, compliance, persistence, switching, or discontinuations of medications using automated dispensing data (pharmacy records). Two study investigators independently reviewed the abstracts and articles to determine relevant studies according to specified criteria. Results: A total of 136 articles met the criteria for evaluation. The types of measures of adherence and persistence commonly reported include the medication possession ratio and related measures of medication availability (77 studies), discontinuation/continuation (58 studies), switching (34 studies), medication gaps (13 studies), refill compliance (7 studies), and retentiveness/turbulence (4 studies). Specific issues considered include the assessment of exposed time to drug therapy and specification of the follow‐up period. Conclusions: The terminology, definitions, and methods to determine adherence and persistence differ greatly in the published literature. The appropriateness and choice of the specific measure employed should be determined by the overall goals of the study, as well as the relative advantages and limitations of the measures. Copyright © 2006 John Wiley & Sons, Ltd.
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Cites
Patient adherence to treatment: three decades of research. A comprehensive review
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Depression and Diabetes: Impact of Depressive Symptoms on Adherence, Function, and Costs
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A systematic review of adherence with medications for diabetes
Cramer, J. A. (2004) · Diabetes Care · doi:10.2337/diacare.27.5.1218 · Cited by 1,203
The assessment of refill compliance using pharmacy records: Methods, validity, and applications
Steiner, J. F., & Prochazka, A. V. (1997) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(96)00268-5 · Cited by 1,193
Measurement, Correlates, and Health Outcomes of Medication Adherence Among Seniors
Vik, S. A., Maxwell, C. J., & Hogan, D. B. (2004) · Annals of Pharmacotherapy · doi:10.1345/aph.1d252 · Cited by 403
Jaime, J., Speckman, J. L., Salas, M., Raggio, G., & Jackson, J. D. (1999) · Europe PMC (PubMed Central) · Cited by 272
Nonadherence in Asthmatic Patients: Is there a Solution to the Problem ?
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A Critical Evaluation of the Methodology of the Literature on Medication Compliance
Nichol, M. B., Venturini, F., & Sung, J. (1999) · Annals of Pharmacotherapy · doi:10.1345/aph.18233 · Cited by 114
Persistence with drug therapy: a practical approach using administrative claims data.
Dezii, C. M. (2001) · PubMed · Cited by 93
Risk factors for antihypertensive medication refill failure by patients under Medicaid managed care
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Cited by
A new taxonomy for describing and defining adherence to medications
Vrijens, B., De Geest, S., Hughes, D. A., Przemyslaw, K., Demonceau, J., Ruppar, T., Dobbels, F., Fargher, E., Morrison, V., Lewek, P., et al. (2012) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2012.04167.x · Cited by 2,028
Medication Adherence: Its Importance in Cardiovascular Outcomes
Ho, P. M., Bryson, C. L., & Rumsfeld, J. S. (2009) · Circulation · doi:10.1161/circulationaha.108.768986 · Cited by 1,488
Medication adherence measures: An overview
Lam, W. Y., & Fresco, P. (2015) · BioMed Research International · doi:10.1155/2015/217047 · Cited by 1,308
Mazzaglia, G., Ambrosioni, E., Alacqua, M., Filippi, A., Sessa, E., Immordino, V., Borghi, C., Brignoli, O., Caputi, A. P., Cricelli, C., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.830299 · Cited by 637
Grenard, J. L., Munjas, B. A., Adams, J. L., Suttorp, M., Maglione, M., McGlynn, E. A., & Gellad, W. F. (2011) · Journal of General Internal Medicine · doi:10.1007/s11606-011-1704-y · Cited by 635
Metadata
- Authors
- Andrade, S. E., Kahler, K. H., Frech, F., & Chan, K. A.
- Venue
- Pharmacoepidemiology and Drug Safety
- Publisher
- Wiley
- Published
- 2006-03-02
- Volume
- 15
- Issue
- 8
- Pages
- 565-574
- ISSN
- 1053-8569 (ISSN-L)
- 1099-1557
- OpenAlex
- W2063844762
- Cited by
- 1,079
- References
- 17
- FWCI
- 18.35
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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