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Cited by 1,028Polysaccharides Composition and ApplicationsHydrogels: synthesis, properties, applicationsAdvanced Drug Delivery Systems

The DOI matches its Crossref record; 521 of the 527 references it cites were found in a registry or an index.

Main properties and current applications of some polysaccharides as biomaterials

Rinaudo, Marguerite·2008·Polymer International
DOI 10.1002/pi.2378
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Abstract

This review concerns the applications of some polysaccharides in the domain of biomaterials and bioactive polymers. Natural polysaccharides from different sources have been studied for a long time, and their main properties are summarized in this paper; some of their derivatives obtained by chemical modification are also described. The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan, hyaluronan and alginates. Alginates are well known for their property of forming a physical gel in the presence of divalent counterions (Ca, Ba, Sr) whereas carrageenans form a thermoreversible gel; these seaweed polysaccharides are mainly used to encapsulate different materials (cells, bacteria, fungi). Other promising systems are the electrostatic complexes formed when an anionic polysaccharide is mixed with a cationic polysaccharide (e.g. alginate/chitosan or hyaluronan/chitosan). An important development of the applications of polysaccharides can be predicted for the next few years in relation to their intrinsic properties such as biocompatibility and biodegradability in the human body for some of them; they are also renewable and have interesting physical properties (film‐forming, gelling and thickening properties). In addition, they are easily processed in different forms such as beads, films, capsules and fibres. Copyright © 2007 Society of Chemical Industry

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Metadata

Authors
Rinaudo, M.
Affiliations
Centre National de la Recherche Scientifique (FR)
Corresponding author
Rinaudo, Marguerite
ORCID
Rinaudo, Marguerite
Venue
Polymer International
Publisher
Wiley
Published
2007-10-09
Volume
57
Issue
3
Pages
397-430
ISSN
  • 0959-8103 (ISSN-L)
  • 1097-0126
DOI
10.1002/pi.2378
OpenAlex
W2021252942
Cited by
1,028
References
527
Citations by year
2026: 45 · 2025: 51 · 2024: 50 · 2023: 64 · 2022: 63 · 2021: 67 · 2020: 87 · 2019: 58 · 2018: 55 · 2017: 68 · 2016: 62 · 2015: 59 · 2014: 70 · 2013: 58 · 2012: 51
FWCI
39.52
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Polymer International (publishedVersion)
  • HAL (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
  • Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Keywords
polysaccharides, biomaterials, chitin, chitosan, hyaluronic acid, alginate, carrageenan, seaweed polysaccharides, physical gels, thermoreversible gels, electrostatic complexes, chitosan-alginate, encapsulation, biocompatibility, biodegradability, polysaccharide modification, film-forming properties, thickening properties, bio-based polymers

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