ProSight Lite: Graphical software to analyze top‐down mass spectrometry data

Fellers, Ryan T., Greer, Joseph B., Early, Bryan P., Yu, Xiang, LeDuc, Richard D., Kelleher, Neil L., Thomas, Paul M.·2015·PROTEOMICS

Cited by (247)

Items 101–200 of 247

  1. High resolution top-down experimental strategies on the Orbitrap platform
    Kai Scheffler, Rosa Viner, Eugen Damoc · 2017 · Journal of Proteomics
  2. Native Electron Capture Dissociation Maps to Iron-Binding Channels in Horse Spleen Ferritin
    Owen S. Skinner, Michael O. McAnally, Richard P. Van Duyne, George Chappell Schatz, Kathrin Breuker, Philip Daniel Compton, Neil L. Kelleher · 2017 · Analytical Chemistry
  3. Isotope Depletion Mass Spectrometry (ID-MS) for Accurate Mass Determination and Improved Top-Down Sequence Coverage of Intact Proteins
    Kelly J. Gallagher, Michael Palasser, Sam Hughes, C. Logan Mackay, David P. A. Kilgour, David J. Clarke · 2020 · Journal of the American Society for Mass Spectrometry
  4. Analysis of Viral Spike Protein N-Glycosylation Using Ultraviolet Photodissociation Mass Spectrometry
    Edwin E. Escobar, Shuaishuai Wang, Rupanjan Goswami, Michael B. Lanzillotti, Lei Li, Jason S. McLellan, Jennifer S. Brodbelt · 2022 · Analytical Chemistry
  5. Recent advances in structural mass spectrometry methods in the context of biosimilarity assessment: from sequence heterogeneities to higher order structures
    J.-G. Castel, Sarah Delaux, Oscar Hernandez‐Alba, Sarah Cianférani · 2023 · Journal of Pharmaceutical and Biomedical Analysis
  6. Advances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challenges
    Abhik Mojumdar, Hee-Jin Yoo, Duck‐Hyun Kim, Ji‐Won Park, Sujin Park, Eunji Jeon, Sunhee Choi, Jung Hoon Choi, Moonhee Park, Geul Bang et al. · 2024 · Journal of Analytical Science & Technology
  7. Mass Spectrometry-Based Top-Down Proteomics for Proteoform Profiling of Protein Corona
    S. Sadeghi, Fei Fang, Reyhane Tabatabaeian Nimavard, Qian-Yi Wang, Guijie Zhu, A. Saei, Liang-Liang Sun, M. Mahmoudi · 2025 · Nature Protocols
  8. Pilot Study for Deciphering Post-Translational Modifications and Proteoforms of Tau Protein by Capillary Electrophoresis-Mass Spectrometry
    Fei Fang, Tian Xu, Hsiao‐Tien Chien Hagar, Stacy Hovde, Min‐Hao Kuo, Liangliang Sun · 2024 · Journal of Proteome Research
  9. Quantitative Top-down Proteomics Revealed Kinase Inhibitor-induced Proteoform-level Changes in Cancer Cells
    Trishika Chowdhury, Kellye A. Cupp-Sutton, Yanting Guo, Kevin Gao, Zhi-Tao Zhao, Anthony W. G. Burgett, Si Wu · 2024 · Journal of Proteome Research
  10. Multidimensional Top-Down Proteomics of Brain Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol
    Hae-Min Park, R. Satta, Roderick G Davis, Y. Goo, Richard D. LeDuc, Ryan T. Fellers, Joseph B. Greer, E. V. Romanova, S. Rubakhin, Rex Tai et al. · 2019 · Journal of Proteome Research
  11. Optical Fiber-Enabled Photoactivation of Peptides and Proteins
    Trenton M. Peters-Clarke, Kevin L. Schauer, N. Riley, J. Lodge, M. Westphall, J. Coon · 2020 · Analytical Chemistry
  12. Native mass spectrometry analyses of chaperonin complex TRiC/CCT reveal subunit N-terminal processing and re-association patterns
    Miranda P. Collier, Karen E. Moreira, Kathy H. Li, Yuchan Chen, Daniel N. Itzhak, Rahul S. Samant, Alexander Leitner, Alma L. Burlingame, Judith Frydman · 2021 · Scientific Reports
  13. Revving an Engine of Human Metabolism: Activity Enhancement of Triosephosphate Isomerase via Hemi-Phosphorylation
    Luis F. Schachner, B. D. Soye, S. Ro, Grace E Kenney, Ashley N. Ives, Taojunfeng Su, Y. Goo, Michael C. Jewett, A. Rosenzweig, N. Kelleher · 2022 · ACS Chemical Biology
  14. Ultrahigh Resolution Ion Isolation by Stored Waveform Inverse Fourier Transform 21 T Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.
    Donald F. Smith, Greg T. Blakney, S. Beu, Lissa C. Anderson, Chad R. Weisbrod, C. Hendrickson · 2020 · Analytical Chemistry
  15. MS-TAFI: A Tool for the Analysis of Fragment Ions Generated from Intact Proteins
    Kyle J. Juetten, Jennifer S. Brodbelt · 2022 · Journal of Proteome Research
  16. Coupling 193 nm Ultraviolet Photodissociation and Ion Mobility for Sequence Characterization of Conformationally-Selected Peptides
    Alyssa Q. Stiving, Sophie R. Harvey, Benjamin J. Jones, Bruno Bellina, Jeffery M. Brown, Perdita E. Barran, Vicki Hopper Wysocki · 2020 · Journal of the American Society for Mass Spectrometry
  17. Optimization of Higher-Energy Collisional Dissociation Fragmentation Energy for Intact Protein-Level Tandem Mass Tag Labeling
    Yanting Guo, Trishika Chowdhury, Meena Seshadri, Kellye A. Cupp‐Sutton, Qingyu Wang, Dahang Yu, Si Wu · 2023 · Journal of Proteome Research
  18. Fundamentals and Advances of Orbitrap Mass Spectrometry
    Michaela Ščigelová, Alexander Makarov · 2000 · Wiley eBooks
  19. Establishing a Top-Down Proteomics Platform on a Time-of-Flight Instrument with Electron-Activated Dissociation
    Richard M. Searfoss, Emily Zahn, Zong-Tao Lin, Benjamin A. Garcia · 2025 · Journal of Proteome Research
  20. Ubiquitin Conjugation Probed by Inflammation in Myeloid-Derived Suppressor Cell Extracellular Vesicles
    Katherine R. Adams, Sitara Chauhan, Divya B. Patel, Virginia K. Clements, Yan Wang, Steven M. Jay, Nathan J Edwards, Suzanne Ostrand‐Rosenberg, Catherine Fenselau · 2017 · Journal of Proteome Research
  21. Protein de novo sequencing by top-down and middle-down MS/MS: Limitations imposed by mass measurement accuracy and gaps in sequence coverage
    Lidong He, Chad R. Weisbrod, Alan G. Marshall · 2017 · International Journal of Mass Spectrometry
  22. Deconvolution in mass spectrometry based proteomics
    Xu Guang, Jacek Stupak, Yang Li, Luokai Hu, Bo Guo, Jianjun Li · 2018 · Rapid Communications in Mass Spectrometry
  23. Proteomic and direct analysis in real time mass spectrometry analysis of a Native American ceremonial hat
    Timothy P. Cleland, G. Asher Newsome, R. Eric Hollinger · 2019 · The Analyst
  24. Insights on the Conformational Ensemble of Cyt C Reveal a Compact State during Peroxidase Activity
    Emily E. Chea, Daniel Joseph Deredge, Lisa M. Jones · 2019 · Biophysical Journal
  25. Gas-phase ion/ion chemistry for structurally sensitive probes of gaseous protein ion structure: Electrostatic and electrostatic to covalent cross-linking
    Melanie Cheung See Kit, Verônica V. Carvalho, Jonah Z. Vilseck, Ian Webb · 2021 · International Journal of Mass Spectrometry
  26. Structural Characterization of Carbonic Anhydrase–Arylsulfonamide Complexes Using Ultraviolet Photodissociation Mass Spectrometry
    Inês C. Santos, Jennifer S. Brodbelt · 2021 · Journal of the American Society for Mass Spectrometry
  27. Rapid MRSA detection via tandem mass spectrometry of the intact 80 kDa PBP2a resistance protein
    Jason R. Neil, Arvind Verma, Scott R. Kronewitter, William M. McGee, Christopher Mullen, Marjaana Viirtola, Annika Kotovuori, Herdis Friedrich, Johan Finell, Joni Rannisto et al. · 2021 · Scientific Reports
  28. Implementing Digital-Waveform Technology for Extended m/z Range Operation on a Native Dual-Quadrupole FT-IM-Orbitrap Mass Spectrometer
    Jacob W. McCabe, Benjamin J. Jones, Thomas E. Walker, Robert L. Schrader, Adam P. Huntley, Jixing Lyu, Nathan M. Hoffman, Gordon Anderson, Peter T. A. Reilly, Arthur D. Laganowsky et al. · 2021 · Journal of the American Society for Mass Spectrometry
  29. A multiparameter optimization in middle‐down analysis of monoclonal antibodies by LC–MS/MS
    Jonathan Dhenin, Mathieu Dupré, Karen Druart, Alain Krick, Christine Mauriac, Julia Chamot‐Rooke · 2023 · Journal of Mass Spectrometry
  30. Reassembling protein complexes after controlled disassembly by top-down mass spectrometry in native mode
    Luis F. Schachner, Denise P. Tran, Alexander S. Lee, John P. McGee, Kevin Jooß, Kenneth R. Durbin, Henrique S. Seckler, Lauren M. Adams, Erika N. Cline, Rafael Donadelli Melani et al. · 2021 · International Journal of Mass Spectrometry
  31. Improved Sequence Analysis of Intact Proteins by Parallel Ion Parking during Electron Transfer Dissociation
    Elizabeth M. Duselis, Maria C. Panepinto, John E. P. Syka, Christopher Mullen, Robert A. D’Ippolito, A. Michelle English, Scott A. Ugrin, Jeffrey Shabanowitz, Donald F. Hunt · 2021 · Analytical Chemistry
  32. Top-Down Analysis of Branched Proteins Using Mass Spectrometry
    Chen, Dapeng, Gomes, Fabio, Abeykoon, Dulith, Lemma, Betsegaw, Wang, Yan, Fushman, David, Fenselau, Catherine · 2018 · Analytical Chemistry
  33. Proteomics: Tools of the Trade
    Utpal Bose, Gene L. Wijffels, Crispin A. Howitt, Michelle Lisa Colgrave · 2019 · Advances in experimental medicine and biology
  34. IMTBX and Grppr: Software for Top-Down Proteomics Utilizing Ion Mobility-Mass Spectrometry
    Dmitry M. Avtonomov, Daniel A. Polasky, Brandon T. Ruotolo, Alexey I. Nesvizhskii · 2017 · Analytical Chemistry
  35. Characterization of Structural Hemoglobin Variants by Top-Down Mass Spectrometry and R Programming Tools for Rapid Identification
    Yuan Lin, Archana M. Agarwal, Alan G. Marshall, Lissa C. Anderson · 2021 · Journal of the American Society for Mass Spectrometry
  36. Determining the Location of the α-Synuclein Dimer Interface Using Native Top-Down Fragmentation and Isotope Depletion-Mass Spectrometry
    Kiani Jeacock, Alexandre Chappard, Kelly J. Gallagher, C. Logan Mackay, David P. A. Kilgour, Mathew H. Horrocks, Tilo Kunath, David J. Clarke · 2023 · Journal of the American Society for Mass Spectrometry
  37. Characterizing age-related changes in intact mitochondrial proteoforms in murine hearts using quantitative top-down proteomics
    Andrea Ramírez‐Sagredo, Anju Teresa Sunny, Kellye A. Cupp‐Sutton, Trishika Chowdhury, Zhitao Zhao, Si Wu, Ying Ann Chiao · 2024 · Clinical Proteomics
  38. Application of Multiple Length Cross-linkers to the Characterization of Gaseous Protein Structure
    Melanie Cheung See Kit, Ian Webb · 2022 · Analytical Chemistry
  39. Analysis of Isotopically Depleted Proteins Derived from Escherichia coli and Caenorhabditis elegans Cell Lines by Liquid Chromatography 21 T Fourier Transform-Ion Cyclotron Resonance Mass Spectrometry
    Zeljka Popovic, Lissa C. Anderson, Xuepei Zhang, David Stephen Butcher, Greg T. Blakney, Roman A. Zubarev, Alan G. Marshall · 2023 · Journal of the American Society for Mass Spectrometry
  40. Maximizing Selective Cleavages at Aspartic Acid and Proline Residues for the Identification of Intact Proteins
    David J. Foreman, E. Dziekonski, S. McLuckey · 2018 · Journal of the American Society for Mass Spectrometry
  41. Towards middle-up analysis of polyclonal antibodies: subclass-specific N-glycosylation profiling of murine immunoglobulin G (IgG) by means of HPLC-MS
    Constantin Blöchl, Christof Regl, Christian G. Huber, Petra Winter, Richard Weiss, Therese Wohlschlager · 2020 · Scientific Reports
  42. Mapping paratopes of nanobodies using native mass spectrometry and ultraviolet photodissociation
    Luis A. Macias, Xun Wang, Bryan W. Davies, Jennifer S. Brodbelt · 2022 · Chemical Science
  43. Characterization of Phosphorylated Peptides by Electron-Activated and Ultraviolet Dissociation Mass Spectrometry: A Comparative Study with Collision-Induced Dissociation
    Marion Girod, Delphine Arquier, Amanda Helms, Kyle J. Juetten, Jennifer S. Brodbelt, Jérôme Lemoine, Luke MacAleese · 2024 · Journal of the American Society for Mass Spectrometry
  44. A Universal Spectrum Annotator for Complex Peptidoforms in Mass Spectrometry-Based Proteomics
    Douwe Schulte, Rien W. Leuvenink, Shelley Jager, Albert J. R. Heck, Joost Snijder · 2025 · Analytical Chemistry
  45. Online protein unfolding characterized by ion mobility electron capture dissociation mass spectrometry: cytochrome C from neutral and acidic solutions
    Rebecca L. Cain, Ian Webb · 2023 · Analytical and Bioanalytical Chemistry
  46. All Ion Differential Analysis Refines the Detection of Terminal and Internal Diagnostic Fragment Ions for the Characterization of Biologics Product-Related Variants and Impurities by Middle-down Mass Spectrometry
    François Griaud, Blandine Denefeld, Chi‐Ya Kao‐Scharf, Jérôme Dayer, Manuel Lang, Jianyou Chen, Matthias Berg · 2019 · Analytical Chemistry
  47. Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype
    Peter Francis Doubleday, Luca Fornelli, Neil L. Kelleher · 2020 · Journal of Proteome Research
  48. Center of Mass Calculation in Combination with MS/MS Allows Robust Identification of Single Amino Acid Polymorphisms in Clinical Measurements of Insulin-Like Growth Factor-1
    Anthony D. Maus, Jennifer V. Kemp, Dragana Milosevic, Santosh Renuse, Akhilesh Pandey, Ravinder Jit Singh, Stefan K. G. Grebe · 2019 · Journal of Proteome Research
  49. Capturing RAS oligomerization on a membrane
    Sangho D. Yun, Elena Scott, Jing‐Yuan Chang, Hanieh Bahramimoghaddam, Michael Lynn, Carter Lantz, David H. Russell, Arthur D. Laganowsky · 2024 · Proceedings of the National Academy of Sciences
  50. Increased Single-Spectrum Top-Down Protein Sequence Coverage in Trapping Mass Spectrometers with Chimeric Ion Loading
    Chad R. Weisbrod, Lissa C. Anderson, Joseph B. Greer, Caroline J. DeHart, Christopher L. Hendrickson · 2020 · Analytical Chemistry
  51. Preparing to read the ubiquitin code: characterization of ubiquitin trimers by top‐down mass spectrometry
    Amanda E. Lee, Lucía Geis‐Asteggiante, Emma K. Dixon, Yeji Kim, Tanuja R. Kashyap, Yan Wang, David Fushman, Catherine Fenselau · 2016 · Journal of Mass Spectrometry
  52. Conodipine-P1-3, the First Phospholipases A2 Characterized from Injected Cone Snail Venom*
    Carolina Möller, W. Clay Davis, Evan Clark, Anthony P. DeCaprio, Frank Marí · 2019 · Molecular & Cellular Proteomics
  53. Protamine Characterization by Top-Down Proteomics: Boosting Proteoform Identification with DBSCAN
    Gianluca Arauz‐Garofalo, Meritxell Jodar, Mar Vilanova, Alberto de la Iglesia, Judit Castillo, Ada Soler‐Ventura, Rafael Oliva, Marta Vilaseca, Marina Gay · 2021 · Proteomes
  54. Preparing to read the ubiquitin code: top‐down analysis of unanchored ubiquitin tetramers
    Amanda E. Lee, Lucía Geis‐Asteggiante, Emma K. Dixon, M. Barry Miller, Yan Wang, David Fushman, Catherine Fenselau · 2016 · Journal of Mass Spectrometry
  55. A High-Throughput Workflow for Mass Spectrometry Analysis of Nucleic Acids by Nanoflow Desalting
    Michael B. Lanzillotti, Jennifer S. Brodbelt · 2024 · Analytical Chemistry
  56. A Top-Down Proteomic Assay to Evaluate KRAS4B-Compound Engagement
    R. D'Ippolito, Dana Rabara, Maria Abreu Blanco, Emily O. Alberico, Matthew R. Drew, Nitya Ramakrishnan, Dara Sontan, Stephanie R. T. Widmeyer, Grace M Scheidemantle, S. Messing et al. · 2024 · Analytical Chemistry
  57. A Conformation-Specific Approach to Native Top-down Mass Spectrometry
    Hannah M. Britt, Aisha Ben-Younis, Nathanael Page, Konstantinos Thalassinos · 2024 · Journal of the American Society for Mass Spectrometry
  58. A year (2014–2015) of plants in Proteomics journal. Progress in wet and dry methodologies, moving from protein catalogs, and the view of classic plant biochemists
    Rosa Sánchez‐Lucas, Ângela Mehta, Luís Valledor, Francisco Cabello‐Hurtado, María Cristina Romero-Rodríguez, Lyudmila Simova‐Stoilova, Sekvan Demir, Luis E. Rodriguez‐de‐Francisco, Ana María Maldonado-Alconada, Ana L. Jorrin‐Prieto et al. · 2015 · PROTEOMICS
  59. The redox-sensitive R-loop of the carbon control protein SbtB contributes to the regulation of the cyanobacterial CCM
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  60. Precise Characterization of KRAS4B Proteoforms by Combining Immunoprecipitation with Top-Down Mass Spectrometry
    Lauren M. Adams, Caroline J. DeHart, Neil L. Kelleher · 2021 · Methods in molecular biology
  61. Top-down proteomics: applications, recent developments and perspectives
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  62. Native Top–Down Analysis of Membrane Protein Complexes Directly From In Vitro and Native Membranes
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  63. Quantitative Native Proteomics by Capillary Zone Electrophoresis-Mass Spectrometry
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  64. Quantifying Positional Isomers (QPI) by Top-Down Mass Spectrometry
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  65. FAST MS: Software for the Automated Analysis of Top-Down Mass Spectra of Polymeric Molecules Including RNA, DNA, and Proteins
    Michael Palasser, Kathrin Breuker · 2024 · Journal of the American Society for Mass Spectrometry
  66. Influence of carboxylation on osteocalcin detection by mass spectrometry
    Timothy P. Cleland, Corinne J. Thomas, Caren M. Gundberg, Deepak Vashishth · 2016 · Rapid Communications in Mass Spectrometry
  67. Top-down analysis of disulfide-linked proteins using photoinduced radical reactions and ET-DDC
    Sarju Adhikari, Yu Xia, Scott A. McLuckey · 2019 · International Journal of Mass Spectrometry
  68. TopMSV: A Web-Based Tool for Top-Down Mass Spectrometry Data Visualization
    In Kwon Choi, Tianze Jiang, Sreekanth R. Kankara, Si Wu, Xiaowen Liu · 2021 · Journal of the American Society for Mass Spectrometry
  69. A hybrid spectral library and protein sequence database search strategy for bottom-up and top-down proteomic data analysis
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  70. Proteoform characterization based on top-down mass spectrometry
    Jiancheng Zhong, Yusui Sun, Minzhu Xie, Wei Peng, Chushu Zhang, Fang‐Xiang Wu, Jianxin Wang · 2020 · Briefings in Bioinformatics
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  72. Top-Down Proteomics for the Characterization and Quantification of Calreticulin Arginylation
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  73. Resolution of Apolipoprotein A1 and A2 Proteoforms: Their Cardiometabolic Correlates and Implications for Future Research
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  74. Mapping RNAPII CTD Phosphorylation Reveals That the Identity and Modification of Seventh Heptad Residues Direct Tyr1 Phosphorylation
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  76. A benchmarking protocol for intact protein-level Tandem Mass Tag (TMT) labeling for quantitative top-down proteomics
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  77. Proteomics Mass Spectrometry Data Analysis Tools
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