The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Approaches to labeling and identification of active site residues in glycosidases
Open accessAbstract
Glycosidases play a key role in a number of biological processes and, as such, are of considerable clinical and bio‐technological importance. Knowledge of the identities of catalytically important active site residues is essential for understanding the catalytic mechanism, for enzyme classification, and for targeted bioengineering of glycosidases with altered characteristics. Here we review and discuss traditional strategies and novel approaches based on tandem mass spectrometry for the identification of the key active site residues in glycosidases.
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Cites
New families in the classification of glycosyl hydrolases based on amino acid sequence similarities
Henrissat, B., & Bairoch, A. (1993) · Biochemical Journal · doi:10.1042/bj2930781 · Cited by 1,974
Cited by
Glycosyltransferases: Structures, Functions, and Mechanisms
Lairson, L. L., Henrissat, B., Davies, G. J., & Withers, S. G. (2008) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.76.061005.092322 · Cited by 2,079
Self-citationPayne, C. M., Knott, B. C., Mayes, H. B., Hansson, H., Himmel, M. E., Sandgren, M., Ståhlberg, J., & Beckham, G. T. (2015) · Chemical Reviews · doi:10.1021/cr500351c · Cited by 855
Proteomics: the first decade and beyond
Patterson, S. D., & Aebersold, R. H. (2003) · Nature Genetics · doi:10.1038/ng1106 · Cited by 745
Self-citationChen, R., Dawson, D. W., Pan, S., Ottenhof, N. A., de Wilde, R. F., Wolfgang, C. L., May, D. H., Crispin, D. A., Lai, L. A., Lay, A. R., et al. (2015) · Laboratory Investigation · doi:10.1038/labinvest.2014.128 · Cited by 59
“Using a PDAC survival tissue microarray, a study evaluated 13 putative biomarkers selected from the literature, and identified mucin 1 and mesothelin as biomarkers for predicting aggressiveness of pancreatic cancer biology, outperforming pathologic features and other putative biomarkers 15 .”
Feng, J. (2004) · Glycobiology · doi:10.1093/glycob/cwh110 · Cited by 17
Metadata
- Authors
- Withers, S. G., & Aebersold, R.
- Venue
- Protein Science
- Publisher
- Wiley
- Published
- 1995-03
- Volume
- 4
- Issue
- 3
- Pages
- 361-372
- ISSN
- 0961-8368 (ISSN-L)
- 1469-896X
- OpenAlex
- W2135237902
- Cited by
- 168
- References
- 1
- FWCI
- 4.38
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Withers, S. G., & Aebersold, R. (1995). Approaches to labeling and identification of active site residues in glycosidases. Protein Science. https://doi.org/10.1002/pro.5560040302
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