miR‐96 and autophagy are involved in the beneficial effect of grape seed proanthocyanidins against high‐fat‐diet‐induced dyslipidemia in mice

Shi, Yawei; Jia, Minghan; Xu, Lixia; Fang, Zeng; Wu, Weibin; Zhang, Qi; Chung, Peter; Lin, Ying; Wang, Shenming; Zhang, Yunjian

doi:10.1002/ptr.6318

miR‐96 and autophagy are involved in the beneficial effect of grape seed proanthocyanidins against high‐fat‐diet‐induced dyslipidemia in mice

We aimed to investigate the possible signaling pathways underlying the regulation of grape seed proanthocyanidins extracts (GSPE) on lipid metabolism. One hundred male C57BL/6 mice were divided into four groups: control group (normal diet), GSPE group (normal diet + GSPE), high‐fat diet group (HF…