Eugenol restrains abdominal aortic aneurysm progression with down‐regulations on NF‐κB and COX‐2

Zhai, Ziyi; Zhang, Xianjing; Ding, Yuchao; Huang, Ziming; Li, Qian; Zheng, Mingyue; Cho, Kenka; Dong, Zhihui; Fu, Weiguo; Chen, Zaixing; Jiang, Baohong

doi:10.1002/ptr.7358

Eugenol restrains abdominal aortic aneurysm progression with down‐regulations on NF‐κB and COX‐2

Abdominal aortic aneurysm (AAA) is a lethal disease without available medicine for treatment. This study aimed to evaluate the efficiency of eugenol (4‐allyl‐2‐methoxyphenol) against AAA and the underlying mechanism. Eugenol is the major bioactive component of clove. A mouse AAA model was establi…