The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A method for reducing the time required to match protein sequences with tandem mass spectra
Abstract
An algorithm for reducing the time necessary to match a large set of peptide tandem mass spectra with a list of protein sequences is described. This algorithm breaks the process into multiple steps. A rapid survey step identifies all protein sequences that are reasonable candidates for a match with a set of tandem mass spectra. These candidates are then used as models, which are refined by detailed analysis of the set of tandem mass spectra for evidence of incomplete enzymatic hydrolysis, non‐specific hydrolysis and chemical modifications of amino acid residues resulting from either post‐translational modifications or sample handling. Compared with current one‐step methods for matching proteins to mass spectra, this multiple‐step method can decrease the time required for the calculation by several orders of magnitude. Copyright © 2003 John Wiley & Sons, Ltd.
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Mass spectrometry-based proteomics
Aebersold, R., & Mann, M. (2003) · Nature · doi:10.1038/nature01511 · Cited by 6,955
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Tanner, S., Shu, H., Frank, A., Wang, L.-C., Zandi, E., Mumby, M., Pevzner, P. A., & Bafna, V. (2005) · Analytical Chemistry · doi:10.1021/ac050102d · Cited by 567
Tabb, D. L., Vega-Montoto, L., Rudnick, P. A., Variyath, A. M., Ham, A.-J. L., Bunk, D. M., Kilpatrick, L. E., Billheimer, D. D., Blackman, R. K., Cardasis, H. L., et al. (2010) · Journal of Proteome Research · doi:10.1021/pr9006365 · Cited by 551
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Rosenberger, G., Koh, C. C., Guo, T., Röst, H. L., Kouvonen, P., Collins, B. C., Heusel, M., Liu, Y., Caron, E., Vichalkovski, A., et al. (2014) · Scientific Data · doi:10.1038/sdata.2014.31 · Cited by 413
Metadata
- Authors
- Craig, R., & Beavis, R. C.
- Venue
- Rapid Communications in Mass Spectrometry
- Publisher
- Wiley
- Published
- 2003-09-19
- Volume
- 17
- Issue
- 20
- Pages
- 2310-2316
- ISSN
- 0951-4198 (ISSN-L)
- 1097-0231
- OpenAlex
- W2163078532
- Cited by
- 504
- References
- 1
- FWCI
- 8.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- Craig, R., & Beavis, R. C. (2003). A method for reducing the time required to match protein sequences with tandem mass spectra. Rapid Communications in Mass Spectrometry. https://doi.org/10.1002/rcm.1198
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