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Cited by 297

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Matrix‐assisted laser desorption/ionization mass spectrometry of nucleic acids with wavelengths in the ultraviolet and infrared

Nordhoff, E., Ingendoh, A., Cramer, R., Overberg, A., Stahl, B., Karas, M., Hillenkamp, F., Crain, P. F., Chait, B.·1992·Rapid Communications in Mass Spectrometry

Abstract

A number of different matrices have been tested and compared for ultraviolet and ubfrared (UV and IR) matrix‐assisted lasedr desorption/ionization (MALDI) of oligodeoxyribonucleotides and mixtures thereof, as well as ribonucleic acids (tRNA from yeast and rRNA from Ecoli ). A new technique for removing alkali cations from nucleic acid samples during sample preparation on the sample support is demonstrated. The amount of oligonucleotide sample consumed during a typical measurement in IR‐MALDI‐MS was determined.

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Metadata

Authors
Nordhoff, E., Ingendoh, A., Cramer, R., Overberg, A., Stahl, B., Karas, M., Hillenkamp, F., Crain, P. F., & Chait, B.
Venue
Rapid Communications in Mass Spectrometry
Publisher
Wiley
Published
1992-12
Volume
6
Issue
12
Pages
771-776
ISSN
  • 0951-4198 (ISSN-L)
  • 1097-0231
OpenAlex
W2145839720
Cited by
297
References
0
FWCI
15.88
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Matrix‐assisted laser desorption/ionization mass spectrometry of nucleic acids with wavelengths in the ultraviolet and infrared. https://app.cochat.ai/papers/10.1002/rcm.1290061212
The paper
Nordhoff, E., Ingendoh, A., Cramer, R., Overberg, A., Stahl, B., Karas, M., Hillenkamp, F., Crain, P. F., & Chait, B. (1992). Matrix‐assisted laser desorption/ionization mass spectrometry of nucleic acids with wavelengths in the ultraviolet and infrared. Rapid Communications in Mass Spectrometry. https://doi.org/10.1002/rcm.1290061212

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