Blood platelets: Circulating mirrors of neurons?
Open accessAbstract
Blood platelets and resident neurons are fundamentally different cells, with peculiar features in embryological origin, function, and localization. However, they share common characteristics in subcellular organization and in protein composition.1 One of the most intriguing observations is that several proteins are typically expressed in both neurons and circulating platelets. In the latter, their concentrations are unusually high, and they are found to regulate processes such as platelet activation, hemostasis, and thrombosis.
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Platelets share many molecular and functional characteristics with neurons.
“Platelets share many molecular and functional characteristics with neurons [9]”
From Characteristics of platelet-associated parameters and their predictive values in Chinese patients with affective disorders (2022) · cites this paper as [9]
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References 11 · Cited by 53
- Authors
- Canobbio, I.
- Affiliations
- University of Pavia (IT)
- Corresponding author
- Canobbio, Ilaria
- ORCID
- Canobbio, Ilaria
- Venue
- Research and Practice in Thrombosis and Haemostasis
- Publisher
- Elsevier BV
- Published
- 2019-10
- Volume
- 3
- Issue
- 4
- Pages
- 564-565
- ISSN
- 2475-0379 (ISSN-L)
- PMC
- PMC6781913
- OpenAlex
- W2974151115
- Cited by
- 53
- References
- 11
- Citations by year
- 2026: 3 · 2025: 10 · 2024: 12 · 2023: 6 · 2022: 8 · 2021: 8 · 2020: 6
- FWCI
- 3.89
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Research and Practice in Thrombosis and Haemostasis (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Hematology › Platelet Disorders and Treatments
- Health Sciences › Medicine › Hematology › Blood Coagulation and Thrombosis Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
- Keywords
- platelets, neurons, platelet activation, hemostasis, thrombosis, subcellular organization, protein composition
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