The DOI matches its Crossref record.
Evaluation of Quantum Dot Cytotoxicity Based on Intracellular Uptake
Abstract
Nanoparticles, such as quantum dots (QDs), composed of biologically toxic materials degrade in highly oxidative environments. Varying the QD surface coating significantly affects the intracellular uptake of QDs. Although the addition of PEG does not alter the inherent QD cytotoxicity, we demonstrate that the improved biocompatibility due to PEG-substitution arises from decreased intracellular uptake, which allows for biological applications of QDs with minimal toxicity. The image shows the live/dead reagent stain used to quantitate cytotoxicity. PEG: poly(ethylene glycol).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Biological applications of quantum dots
Jamieson, T., Bakhshi, R., Petrova, D., Pocock, R., Imani, M., & Seifalian, A. M. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.014 · Cited by 1,107
Multimodality Imaging Probes: Design and Challenges
Louie, A. (2010) · Chemical Reviews · doi:10.1021/cr9003538 · Cited by 1,044
Quantum dots: bright and versatile in vitro and in vivo fluorescence imaging biosensors
Wegner, K. D., & Hildebrandt, N. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00532e · Cited by 984
Fadeel, B., & Garcia-Bennett, A. E. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.11.008 · Cited by 783
Lee, J., Mahendra, S., & Alvarez, P. J. J. (2010) · ACS Nano · doi:10.1021/nn100866w · Cited by 750
Metadata
- Authors
- Chang, E., Thekkek, N., Yu, W. W., Colvin, V. L., & Drezek, R.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2006-10-27
- Volume
- 2
- Issue
- 12
- Pages
- 1412-1417
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W2122483392
- Cited by
- 370
- References
- 0
- FWCI
- 17.14
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Evaluation of Quantum Dot Cytotoxicity Based on Intracellular Uptake. https://app.cochat.ai/papers/10.1002/smll.200600218
- The paper
- Chang, E., Thekkek, N., Yu, W. W., Colvin, V. L., & Drezek, R. (2006). Evaluation of Quantum Dot Cytotoxicity Based on Intracellular Uptake. Small. https://doi.org/10.1002/smll.200600218
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
