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Cited by 191

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Nanostructured Polymeric Coatings Based on Chitosan and Dopamine‐Modified Hyaluronic Acid for Biomedical Applications

Open access
Neto, Ana I., Cibrão, Ana C., Correia, Clara R., Carvalho, Rita R., Luz, Gisela M., Ferrer, Gloria G., Botelho, Gabriela, Picart, Catherine, Alves, Natália M., Mano, João F.·2014·Small

Abstract

In a marine environment, specific proteins are secreted by mussels and used as a bioglue to stick to a surface. These mussel proteins present an unusual amino acid 3,4‐dihydroxyphenylalanine (known as DOPA). The outstanding adhesive properties of these materials in the sea harsh conditions have been attributed to the presence of the catechol groups present in DOPA. Inspired by the structure and composition of these adhesive proteins, dopamine‐modified hyaluronic acid (HA‐DN) prepared by carbodiimide chemistry is used to form thin and surface‐adherent dopamine films. This conjugate was characterized by distinct techniques, such as nuclear magnetic resonance and ultraviolet spectrophotometry. Multilayer films are developed based on chitosan and HA‐DN to form polymeric coatings using the layer‐by‐layer methodology. The nanostructured films formation is monitored by quartz crystal microbalance. The film surface is characterized by atomic force microscopy and scanning electron microscopy. Water contact angle measurements are also conducted. The adhesion properties are analyzed showing that the nanostructured films with dopamine promote an improved adhesion. In vitro tests show an enhanced cell adhesion, proliferation and viability for the biomimetic films with catechol groups, demonstrating their potential to be used in distinct biomedical applications.

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Crossref · 10.1002/smll.201303568

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Metadata

Authors
Neto, A. I., Cibrão, A. C., Correia, C. R., Carvalho, R. R., Luz, G. M., Ferrer, G. G., Botelho, G., Picart, C., Alves, N. M., & Mano, J. F.
Venue
Small
Publisher
Wiley
Published
2014-03-10
Volume
10
Issue
12
Pages
2459-2469
ISSN
  • 1613-6810 (ISSN-L)
  • 1613-6829
OpenAlex
W2099292518
Cited by
191
References
3
FWCI
5.24
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Nanostructured Polymeric Coatings Based on Chitosan and Dopamine‐Modified Hyaluronic Acid for Biomedical Applications. https://app.cochat.ai/papers/10.1002/smll.201303568
The paper
Neto, A. I., Cibrão, A. C., Correia, C. R., Carvalho, R. R., Luz, G. M., Ferrer, G. G., Botelho, G., Picart, C., Alves, N. M., & Mano, J. F. (2014). Nanostructured Polymeric Coatings Based on Chitosan and Dopamine‐Modified Hyaluronic Acid for Biomedical Applications. Small. https://doi.org/10.1002/smll.201303568

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