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Sub-Micron Polymeric Stomatocytes as Promising Templates for Confined Crystallization and Diffraction Experiments

Open access
Adawy, Alaa, Amghouz, Zakariae, van Hest, Jan C. M., Wilson, Daniela A.·2017·Small

Abstract

The possibility of using sub-micrometer polymeric stomatocytes is investigated to effectuate confined crystallization of inorganic compounds. These bowl-shaped polymeric compartments facilitate confined crystallization while their glassy surfaces provide their crystalline cargos with convenient shielding from the electron beam's harsh effects during transmission electron microscopy experiments. Stomatocytes host the growth of a single nanocrystal per nanocavity, and the electron diffraction experiments reveal that their glassy membranes do not interfere with the diffraction patterns obtained from their crystalline cargos. Therefore, it is expected that the encapsulation and crystallization within these compartments can be considered as a promising template (nanovials) that hold and protect nanocrystals and protein clusters from the direct radiation damage before data acquisition, while they are examined by modern crystallography methodologies such as serial femtosecond crystallography.

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Metadata

Authors
Adawy, A., Amghouz, Z., van Hest, J. C. M., & Wilson, D. A.
Venue
Small
Publisher
Wiley
Published
2017-05-30
Volume
13
Issue
28
Pages
1700642
ISSN
1613-6810 (ISSN-L)
OpenAlex
W2617044253
Cited by
629
References
3
FWCI
42.83
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Sub-Micron Polymeric Stomatocytes as Promising Templates for Confined Crystallization and Diffraction Experiments. https://app.cochat.ai/papers/10.1002/smll.201700642
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Adawy, A., Amghouz, Z., van Hest, J. C. M., & Wilson, D. A. (2017). Sub-Micron Polymeric Stomatocytes as Promising Templates for Confined Crystallization and Diffraction Experiments. Small. https://doi.org/10.1002/smll.201700642

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