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Nanogel engineering for new nanobiomaterials: from chaperoning engineering to biomedical applications
Abstract
Nanosize hydrogels (nanogels) are polymer nanoparticles with three‐dimensional networks, formed by chemical and/or physical cross‐linking of polymer chains. Recently, various nanogels have been designed, with a particular focus on biomedical applications. In this review, we describe recent progress in the synthesis of nanogels and nanogel‐integrated hydrogels (nanogel cross‐linked gels) for drug‐delivery systems (DDS), regenerative medicine, and bioimaging. We also discuss chaperone‐like functions of physical cross‐linking nanogel (chaperoning engineering) and organic‐inorganic hybrid nanogels. © 2010 The Japan Chemical Journal Forum and Wiley Periodicals, Inc. Published online in Wiley InterScience (www.interscience.wiley.com)DOI 10.1002/tcr.201000008
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Cites
The effect of particle design on cellular internalization pathways
Gratton, S. E. A., Ropp, P. A., Pohlhaus, P. D., Luft, J. C., Madden, V. J., Napier, M. E., & DeSimone, J. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801763105 · Cited by 2,918
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Hydrogels as intelligent materials: A brief review of synthesis, properties and applications
Mahinroosta, M., Jomeh Farsangi, Z., Allahverdi, A., & Shakoori, Z. (2018) · Materials Today Chemistry · doi:10.1016/j.mtchem.2018.02.004 · Cited by 551
Recent Advances in Design of Functional Biocompatible Hydrogels for Bone Tissue Engineering
Xue, X., Hu, Y., Deng, Y., & Su, J. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202009432 · Cited by 532
Micro- and nanogels with labile crosslinks – from synthesis to biomedical applications
Zhang, X., Malhotra, S., Molina, M., & Haag, R. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00341a · Cited by 364
Micelle-nanogel platform for ferulic acid ocular delivery
Grimaudo, M. A., Amato, G., Carbone, C., Diaz-Rodriguez, P., Musumeci, T., Concheiro, A., Alvarez-Lorenzo, C., & Puglisi, G. (2020) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2019.118986 · Cited by 63
Metadata
- Authors
- Sasaki, Y., & Akiyoshi, K.
- Venue
- The Chemical Record
- Publisher
- Wiley
- Published
- 2010-09-10
- Volume
- 10
- Issue
- 6
- Pages
- 366-376
- ISSN
- 1527-8999 (ISSN-L)
- 1528-0691
- OpenAlex
- W2144634745
- Cited by
- 412
- References
- 1
- FWCI
- 8.58
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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