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Mitochondrial Nitric Oxide Synthase: A Ubiquitous Regulator of Oxidative Phosphorylation?
Open accessAbstract
In this article we demonstrate the immunocytochemical localization of nitric oxide synthase in mitochondria isolated from heart, skeletal muscle, and kidney, using a monoclonal antibody directed against the endothelial form of nitric oxide synthase. The possibility that mitochondrially located nitric oxide synthase is a ubiquitous regulator of mitochondrial oxidative phosphorylation in mammalian cells is discussed.
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Citations
Cited by
Nitric oxide synthases: structure, function and inhibition
ALDERTON, W. K., COOPER, C. E., & KNOWLES, R. G. (2001) · Biochemical Journal · doi:10.1042/bj3570593 · Cited by 4,110
Wink, D. A., & Mitchell, J. B. (1998) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00092-6 · Cited by 1,606
Mitochondria and reactive oxygen species
Kowaltowski, A. J., de Souza-Pinto, N. C., Castilho, R. F., & Vercesi, A. E. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.05.004 · Cited by 1,162
Physiology of Nitric Oxide in Skeletal Muscle
Stamler, J. S., & Meissner, G. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.1.209 · Cited by 1,080
Nitric oxide synthases: which, where, how, and why?
Michel, T., & Feron, O. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119750 · Cited by 1,011
Metadata
- Authors
- Bates, T. E., Loesch, A., Burnstock, G., & Clark, J. B.
- Venue
- Biochemical and Biophysical Research Communications
- Publisher
- Elsevier BV
- Published
- 1996-01
- Volume
- 218
- Issue
- 1
- Pages
- 40-44
- ISSN
- 0006-291X (ISSN-L)
- OpenAlex
- W2030142800
- Cited by
- 245
- References
- 0
- FWCI
- 9.81
- Type
- journal article
- Language
- en
- Open access
- green
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- Bates, T. E., Loesch, A., Burnstock, G., & Clark, J. B. (1996). Mitochondrial Nitric Oxide Synthase: A Ubiquitous Regulator of Oxidative Phosphorylation? Biochemical and Biophysical Research Communications. https://doi.org/10.1006/bbrc.1996.0008
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
