Increased Insulin Secretion and Glucose Tolerance in Mice Lacking Islet Amyloid Polypeptide (Amylin)

Gebre-Medhin, Samuel, Mulder, Hindrik, Pekny, Milos, Westermark, Gunilla, Törnell, Jan, Westermark, Per, Sundler, Frank, Ahrén, Bo +1 more·1998·Biochemical and Biophysical Research Communications

Cited by (145)

Items 101–145 of 145

  1. Postnatally disturbed pancreatic islet cell distribution in human islet amyloid polypeptide transgenic mice.
    H. Wong, Ah-Ren Bo, C. J. M. Lips, J. Höppener, F. Sundler · 2003 · Regulatory Peptides
  2. An INSULIN and IAPP dual reporter enables tracking of functional maturation of stem cell-derived insulin producing cells
    Carmen L. Bayly, Xiao-Qing Dai, Cuilan Nian, Paul C. Orban, C. Bruce Verchere, Patrick E. MacDonald, Francis C. Lynn · 2024 · Molecular Metabolism
  3. Understanding the mechanism of amylin aggregation: From identifying crucial segments to tracing dominant sequential events to modeling potential aggregation suppressors
    Ritama Ghosh, Shreyan Ghosh, Atanu Das · 2022 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  4. Amylin deposition activates HIF1α and 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 (PFKFB3) signaling in failing hearts of non-human primates
    Miao Liu, Nan Li, Chun Qu, Yilin Gao, Lijie Wu, Liangbiao George Hu · 2021 · Communications Biology
  5. Islet Amyloid Polypeptide Regulates Multiple Steps in Stimulus-Secretion Coupling of β Cells in Rat Pancreatic Islets
    Feng Wang, J. Permert, C. Östenson · 2000
  6. 7 - The Prohormone Convertases and Precursor Processing in Protein Biosynthesis
    D. Steiner · 2002 · The Enzymes
  7. Amylin-like immunoreactivity in pancreatic X cells of the black-spotted frog Rana (Pelophylax) nigromaculata
    Hirohumi Suzuki, Toshiharu Yamamoto · 2014 · Tissue and Cell
  8. Islet amyloid polypeptide does not suppress pancreatic cancer
    Austin J. Taylor, Evgeniy Panzhinskiy, Paul C. Orban, Francis C. Lynn, David F. Schaeffer, James D. Johnson, Janel L. Kopp, C. Bruce Verchere · 2023 · Molecular Metabolism
  9. Effects of Amylin Against Amyloid-β-Induced Tauopathy and Synapse Loss in Primary Neurons
    Qini Gan, Hongbo Yao, Hana Na, Heather I. Ballance, Qiushan Tao, Lorene Leung, Hua Tian, Haihao Zhu, Benjamin L. Wolozin, Wei Qiao Qiu · 2019 · Journal of Alzheimer s Disease
  10. Amyloids as Sensors and Protectors (ASAP) Hypothesis
    Rachel Petrofes Chapa, Michael A. Emery, Janelle N. Fawver, Ian V.J. Murray · 2012 · Journal of Alzheimer s Disease
  11. Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide.
    S. Andrikopoulos, R. Hull, C. Verchere, Feng Wang, Shani M. Wilbur, T. Wight, L. Marzban, S. Kahn · 2004 · American Journal of Physiology. Endocrinology and Metabolism
  12. On the Role of Islet Amyloid Polypeptide in Glucose Intolerance and Anorexia of Pancreatic Cancer
    Margery K. Herrington, Urban Arnelo, Johan Permert · 2001 · Pancreatology
  13. Pancreatic Islet Amyloid and Diabetes
    Anne Clark, J. H. Moffitt · 2007 · Springer eBooks
  14. Amylin Pharmacology in Alzheimer’s Disease Pathogenesis and Treatment
    Gemma Casadesus, Rachel R. Corrigan, Helen Piontkivska · 2021 · Current Neuropharmacology
  15. Unaltered pancreatic islet blood perfusion in islet amyloid polypeptide-deficient mice.
    P. Carlsson, E. Karlsson, H. Mulder, S. Gebre-Medhin · 2002 · European Journal of Endocrinology
  16. Neuropeptides and the Control of Energy Homeostasis
    S C Woods, P. A. Rushing, Randy J. Seeley · 2001 · KARGER eBooks
  17. Oral Amylin Treatment Reduces the Pathological Cascade of Alzheimer’s Disease in a Mouse Model
    Hana Na, Hua Tian, Zheng-Rong Zhang, Qiang Li, Jack B. Yang, Liam Mcparland, Qini Gan, Wei Q. Qiu · 2021 · American Journal of Alzheimers Disease & Other Dementias
  18. Calcitonin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
    Debbie L. Hay, David R. Poyner, Christopher S. Walker · 2019 · IUPHAR/BPS Guide to Pharmacology CITE
  19. Biochemical Alterations Induced by Amylin in Wistar Rats
    M. Soliman, Z. Ibrahim · 2013 · American Journal of Pharmacology and Toxicology
  20. Steve Woods's contribution to research on amylin's eating inhibitory effect.
    T. Lutz · 2011 · Physiology and Behavior
  21. Metabolic Syndrome
    A. Farooqui · 2013 · Springer: New York
  22. Characterization of 0839 – A tool compound for pre-clinical mode-of-action studies of amylin analogues such as cagrilintide
    Sanaz Gabery, Tine Glendorf, Borja Ballarín-González, Kent Pedersen, Thomas Kruse, Kirsten Raun, Rune E. Kuhre · 2025 · Life Sciences
  23. Biosynthesis, Processing, and Secretion of the Islet Hormones
    Donald F. Steiner, Christopher J. Rhodes, Louis H. Philipson, Graeme I. Bell, Shu Jin Chan · 2015 · Elsevier eBooks
  24. Peripheral amylin modulation rebalances brain glycolysis and Tau-Ser214 phosphorylation via cAMP-PKA signaling
    Ravichandra Shivalingappa Davargaon, Nirmal Verma, Deepak Kotiya, Noah S. Leibold, Gopal V. Velmurugan, Han Ly, Kuey Chu Chen, Daniel Ruíz, Victor G. Corces, Huazhen Liu et al. · 2026 · iScience
  25. Metabolic Syndrome as a Risk Factor for Alzheimer Disease
    A. A. Farooqui · 2013 · Springer eBooks
  26. Physiological and Pathophysiological Role of Islet Amyloid Polypeptide (IAPP, Amylin)
    Gunilla Torstensdotter Westermark · 2011 · Springer eBooks
  27. Brainstem-Hypothalamic Neuropeptides and the Regulation of Feeding
    Simon M. Luckman · 2007 · Elsevier eBooks
  28. Calcitonin receptors in GtoPdb v.2021.2
    Debbie L. Hay, David R. Poyner, Christopher S. Walker · 2021 · IUPHAR/BPS Guide to Pharmacology CITE
  29. Islet Amyloid Polypeptide/GLP‐1/Exendin
    Laurie L. Baggio, Daniel J. Drucker · 2003
  30. Roles of Gut Hormones in the Regulation of Food Intake and Body Weight
    Lidia Castagneto‐Gissey, James Rossario Casella Mariolo, Geltrude Mingrone · 2017 · Endocrinology
  31. Chapter 140 – Amylin/CGRP
    T. Lutz · 2013
  32. Cytotoxic Mechanisms of Islet Amyloid Polypeptide in the Pathogenesis of Type-2 Diabetes Mellitus (T2DM)
    Theri Leica Degaki, Dahabada H. J. Lopes, Mari Cleide Sogayar · 2011 · Springer eBooks
  33. Amylin and Calcitonin Gene-Related Peptide
    Dorit Naot, Ian R. Reid, Jill Cornish · 2008 · Elsevier eBooks
  34. Role of Amylin and Calcitonin-Gene-Related Peptide (CGRP) in the Control of Food Intake
    T. Lutz · 2006 · Elsevier eBooks
  35. Atomistic islet amyloid polypeptide fibril simulations reveal interplay of amyloid kinetic and mechanical stability
    L. Tepper, A. Pavlov, Beate Koksch, R. Netz · 2026 · Communications Materials
  36. Calcitonin receptors in GtoPdb v.2025.3
    Michael L. Garelja, Debbie L. Hay, D. Poyner, Christopher S. Walker · 2025 · IUPHAR/BPS Guide to Pharmacology CITE
  37. Of Mice and Men: Translational Research on Amylin Agonism
    Jonathan David Roth, Christine M. Mack, James L. Trevaskis, David G. Parkes · 2011
  38. CT, CGRP, Amylin, and Adrenomedullins
    Debbie L. Hay, David R. Poyner · 2009 · CRC Press eBooks
  39. Islet Amyloid Polypeptide (IAPP)/Amylin
    J. Hoppener · 2002 · Wiley Encyclopedia of Molecular Medicine
  40. Amylin and Insulin Interact to Reduce Food Intake in Rats
    P. Rushing, T. Lutz, R. Seeley, S. Woods · 2000 · Hormone and Metabolic Research
  41. The role of islet amyloid and CHOP in islet graft dysfunction and failure
    K. Potter · 2011
  42. Insights into the Function of Intermedin/Adrenomedullin 2
    Chia Lin Chang, Sheau Yu Hsu · 2009 · Springer eBooks
  43. Amylin sensitivity and secretion following diet-induced obesity in rats
    M. Rossier · 2010
  44. Chapter 23 A Path to Innovation: Gene Knockouts Model New Drug Action
    Brian Zambrowicz, Arthur Sands · 2009 · Annual reports in medicinal chemistry
  45. Amylin and Calcitonin Gene-Related Peptide
    Ian R. Reid, Jill Cornish · 2002 · Elsevier eBooks