WHO Requirements for the Use of Animal Cells asin vitroSubstrates for the Production of Biologicals (Requirements for Biological Susbstances No. 50)
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
WHO considers residual HCD a process impurity that lowers product safety and should be removed as much as possible.
“the World Health Organization (WHO) considers residual HCD a process impurity that lowers product safety and should be removed as much as possible [8].”
From Evaluation of the Efficacy of the Vaccine Production Process in Removing Residual Host Cell DNA from the Vero Cell Rabies Vaccine (2024) · cites this paper as [8]
Cited by
Sorted by citations
Li, J., Pan, R., Yue, F., Gao, T., Wu, X., Shi, L., Wang, Y., Zhao, D., Lan, Z., Chen, H., et al. (2024) · Vaccines · doi:10.3390/vaccines12121379 · Cited by 8 · see citing works
- Authors
- Grachev, V. P., Magrath, D. I., & Griffiths, E.
- Affiliations
- World Health Organization (CH)
- Venue
- Biologicals
- Publisher
- Elsevier BV
- Published
- 1998-09
- Volume
- 26
- Issue
- 3
- Pages
- 175-193
- ISSN
- 1045-1056 (ISSN-L)
- OpenAlex
- W62943476
- Cited by
- 65
- References
- 0
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 3 · 2023: 1 · 2022: 8 · 2021: 3 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 1 · 2015: 3 · 2014: 4 · 2013: 3 · 2012: 3
- FWCI
- 0.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biologicals (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Viral Infectious Diseases and Gene Expression in Insects
- Health Sciences › Medicine › Hepatology › Hepatitis C virus research
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Virus Infections Studies
- Keywords
- hepatitis C virus, HCVcc, serum-free culture, Huh7.5 cells, HCV vaccine, infectivity titer, co-receptors, CD81, LDL receptor, scavenger receptor class B type I, clathrin-mediated endocytosis, neutralizing antibodies
- MeSH terms
- Animals, Antibodies, Monoclonal, Biological Products, Cell Line, Cells, Cultured, DNA, Drug Contamination, Humans, Quality Control, Risk Factors, Viruses, Cell Culture Techniques
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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