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The Discovery of Insulin
Abstract
In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius.
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“In the 1920s, having developed a transformative and lifesaving therapy, the Toronto team faced an almost impossible challenge, and they struggled at the outset to produce enough insulin to meet a rapidly growing demand and to distribute insulin in a fashion that was equitable1.”
From 100 years of insulin: celebrating the past, present and future of diabetes therapy (2021) · cites this paper as [1]
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Insulin signaling in health and disease
White, M. F. (2003) · Science · doi:10.1126/science.1092952 · Cited by 733
Amiel, S. A., Aschner, P., Childs, B., Cryer, P. E., de Galan, B. E., Frier, B. M., Gonder-Frederick, L., Heller, S. R., Jones, T., Khunti, K., et al. (2019) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(18)30315-2 · Cited by 526
A New Approach to the Oral Administration of Insulin and Other Peptide Drugs
Saffran, M., Kumar, G. S., Savariar, C. M., Burnham, J. C., Williams, F. E., & Neckers, D. C. (1986) · Science · doi:10.1126/science.3526553 · Cited by 469
Assessing Glycemia in Diabetes Using Self-monitoring Blood Glucose and Hemoglobin A 1c
Saudek, C. D., Derr, R. L., & Kalyani, R. R. (2006) · JAMA · doi:10.1001/jama.295.14.1688 · Cited by 373
Clinical islet transplantation: advances and immunological challenges
Ricordi, C., & Strom, T. B. (2004) · Nature reviews. Immunology · doi:10.1038/nri1332 · Cited by 370
Metadata
- Authors
- Bliss, M.
- Corresponding author
- Bliss, Michael
- Venue
- Palgrave Macmillan UK eBooks
- Publisher
- Palgrave Macmillan UK
- Published
- 1982
- OpenAlex
- W1984896763
- Cited by
- 524
- References
- 0
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 4 · 2023: 20 · 2022: 9 · 2021: 28 · 2020: 15 · 2019: 10 · 2018: 11 · 2017: 13 · 2016: 21 · 2015: 20 · 2014: 20 · 2013: 20 · 2012: 12
- FWCI
- 73.34
- Type
- book
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Palgrave Macmillan UK eBooks (publishedVersion)
- University of Toronto Press eBooks (publishedVersion)
- University of Chicago Press eBooks (publishedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Social Sciences › Arts and Humanities › History › Medical History and Innovations
- Social Sciences › Arts and Humanities › History and Philosophy of Science › History of Science and Medicine
- Health Sciences › Medicine › Pharmacology (medical) › Historical Medical Research and Treatments
- Keywords
- insulin, insulin discovery, history of medicine, scientific discovery, scientific competition, diabetes mellitus, history of endocrinology
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