Toxicology of Perchlorate
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Perchlorate acts as a chaotrope that reduces protein stability, making oxidized Cl species on Mars major obstacles to human, plant, and microbial use of regolith for ISRU.
“Regardless of formation processes, the widely distributed oxidized Cl -species on Mars will pose major obstacles to human, plant, and microbial use of regolith for ISRU due to its toxicity, since perchlorate acts as a chaotrope that reduces the stability of proteins (J.J. J. Clark, 2000).”
From Simple and effective remediation strategies of Martian perchlorates (2026) · cites this paper as J.J. J. Clark, 2000
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Simple and effective remediation strategies of Martian perchlorates
Coker, H. R., Denvir, A. C., & Howe, J. A. (2026) · Soil Science Society of America Journal · doi:10.1002/saj2.70201 · Cited by 1 · see citing works
- Authors
- Clark, J. J. J.
- Corresponding author
- Clark, James J. J.
- Venue
- Perchlorate in the Environment
- Publisher
- Springer US
- Published
- 2000
- Pages
- 15-29
- OpenAlex
- W2211973023
- Cited by
- 66
- References
- 0
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 2 · 2023: 2 · 2021: 1 · 2020: 3 · 2019: 2 · 2017: 1 · 2016: 1 · 2014: 4 · 2012: 2
- FWCI
- 9.65
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Springer eBooks (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Chemical Analysis and Environmental Impact
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Water Treatment and Disinfection
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Pesticide Exposure and Toxicity
- Keywords
- perchlorate, toxicology, ammonium perchlorate, potassium perchlorate, perchloric acid, perchlorate salts, Graves' disease, hypothyroidism treatment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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