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Cell Viability Assays: Introduction
Abstract
The measurement of cell viability plays a fundamental role in all forms of cell culture. Sometimes it is the main purpose of the experiment, such as in toxicity assays. Alternatively, cell viability can be used to -correlate cell behaviour to cell number, providing a more accurate picture of, for example, anabolic -activity. There are wide arrays of cell viability methods which range from the most routine trypan blue dye exclusion assay to highly complex analysis of individual cells, such as using RAMAN microscopy. The cost, speed, and complexity of equipment required will all play a role in determining the assay used. This chapter aims to provide an overview of many of the assays available today.
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O'Brien, J., Wilson, I., Orton, T., & Pognan, F. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01606.x · Cited by 3,446
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Guidelines for cell viability assays
Kamiloglu, S., Sari, G., Ozdal, T., & Capanoglu, E. (2020) · Food Frontiers · doi:10.1002/fft2.44 · Cited by 769
Stockert, J. C., Horobin, R. W., Colombo, L. L., & Blázquez-Castro, A. (2018) · Acta Histochemica · doi:10.1016/j.acthis.2018.02.005 · Cited by 674
Toxicity of Nanomaterials: Exposure, Pathways, Assessment, and Recent Advances
Ganguly, P., Breen, A., & Pillai, S. C. (2018) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.8b00068 · Cited by 341
Fang, X., Wu, C., Li, H., Yuan, W., & Wang, X. (2018) · Toxicology and Industrial Health · doi:10.1177/0748233717742262 · Cited by 36
Metadata
- Authors
- Stoddart, M. J.
- Venue
- Methods in Molecular Biology
- Publisher
- Humana Press
- Published
- 2011
- Volume
- 740
- Pages
- 1-6
- ISSN
- 1064-3745 (ISSN-L)
- 1940-6029
- OpenAlex
- W157943544
- Cited by
- 270
- References
- 1
- FWCI
- 14.78
- Type
- book chapter
- Language
- en
- Open access
- closed
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