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Fundamentals of Enzyme Kinetics
Abstract
This chapter provides a general introduction to the kinetics of enzyme-catalyzed reactions, with a focus on drug-metabolizing enzymes. A prerequisite to understanding enzyme kinetics is having a clear grasp of the meanings of "enzyme" and "catalysis." Catalysts are reagents that can increase the rate of a chemical reaction without being consumed in the reaction. Enzymes are proteins that form a subset of catalysts. These concepts are further explored below.
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Cites
A new look at the statistical model identification
Akaike, H. (1974) · IEEE Transactions on Automatic Control · doi:10.1109/tac.1974.1100705 · Cited by 51,879
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Inhibition of α-amylase activity by cellulose: Kinetic analysis and nutritional implications
Dhital, S., Gidley, M. J., & Warren, F. J. (2015) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2015.01.039 · Cited by 271
Golub, E., Albada, H. B., Liao, W.-C., Biniuri, Y., & Willner, I. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.5b09457 · Cited by 264
Johnson, C. W., Reid, D., Parker, J. A., Salter, S., Knihtila, R., Kuzmic, P., & Mattos, C. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.778886 · Cited by 133
Inverse problems in systems biology
Engl, H. W., Flamm, C., Kügler, P., Lu, J., Müller, S., & Schuster, P. (2009) · Inverse Problems · doi:10.1088/0266-5611/25/12/123014 · Cited by 122
Metadata
- Authors
- Seibert, E., & Tracy, T. S.
- Venue
- Methods in Molecular Biology
- Publisher
- Humana Press
- Published
- 2014
- Volume
- 1113
- Pages
- 9-22
- ISSN
- 1064-3745 (ISSN-L)
- 1940-6029
- OpenAlex
- W2419095119
- Cited by
- 370
- References
- 1
- FWCI
- 108.00
- Type
- book chapter
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
