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Cited by 593

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Deep MR to CT Synthesis Using Unpaired Data

Open access
Wolterink, Jelmer M., Dinkla, Anna M., Savenije, Mark H. F., Seevinck, Peter R., van den Berg, Cornelis A. T., Išgum, Ivana·2017·Lecture Notes in Computer Science

Abstract

MR-only radiotherapy treatment planning requires accurate MR-to-CT synthesis. Current deep learning methods for MR-to-CT synthesis depend on pairwise aligned MR and CT training images of the same patient. However, misalignment between paired images could lead to errors in synthesized CT images. To overcome this, we propose to train a generative adversarial network (GAN) with unpaired MR and CT images. A GAN consisting of two synthesis convolutional neural networks (CNNs) and two discriminator CNNs was trained with cycle consistency to transform 2D brain MR image slices into 2D brain CT image slices and vice versa. Brain MR and CT images of 24 patients were analyzed. A quantitative evaluation showed that the model was able to synthesize CT images that closely approximate reference CT images, and was able to outperform a GAN model trained with paired MR and CT images.

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Metadata

Authors
Wolterink, J. M., Dinkla, A. M., Savenije, M. H. F., Seevinck, P. R., van den Berg, C. A. T., & Išgum, I.
Venue
Lecture Notes in Computer Science
Published
2017
Pages
14-23
ISSN
  • 0302-9743 (ISSN-L)
  • 1611-3349
OpenAlex
W2745006834
Cited by
593
References
1
FWCI
18.77
Type
conference paper
Language
en
Open access
green

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CoChat. (2026). Citation check: Deep MR to CT Synthesis Using Unpaired Data. https://app.cochat.ai/papers/10.1007/978-3-319-68127-6_2
The paper
Wolterink, J. M., Dinkla, A. M., Savenije, M. H. F., Seevinck, P. R., van den Berg, C. A. T., & Išgum, I. (2017). Deep MR to CT Synthesis Using Unpaired Data. Lecture Notes in Computer Science. https://doi.org/10.1007/978-3-319-68127-6_2

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