Natural Products from Sponges

Gracilioethers E–J, new oxygenated polyketides from the marine sponge Plakinastrella mamillaris

Festa, C., Marino, S. D., D’Auria, M. V., et al. (2012) · Tetrahedron · doi:10.1016/j.tet.2012.09.106 · Cited by 45

Globostelletins A–I, cytotoxic isomalabaricane derivatives from the marine sponge Rhabdastrella globostellata

Li, J., Xu, B., Cui, J., et al. (2010) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2010.05.029 · Cited by 44

Absolute stereostructures of halenaquinol and halenaquinol sulfate, pentacyclic hydroquinones from the okinawan marine sponge xestospongia sapra, as determined by theoretical calculation of CD spectra

Kobayashi, M., Shimizu, N., Kitagawa, I., et al. (1985) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)89263-1 · Cited by 44

Antineoplastic agents. 193. Isolation and structure of the cyclic peptide hymenistatin 1

Pettit, G. R., Clewlow, P. J., Dufresne, C., Doubek, D. L., Cerny, R. L., & Rützler, K. (1990) · Canadian Journal of Chemistry · doi:10.1139/v90-110 · Cited by 44

A Novel Cytotoxic Macrolide, Superstolide B, Related to Superstolide A, from the New Caledonian Marine Sponge Neosiphonia superstes

D’Auria, M. V., Paloma, L. G., Minale, L., et al. (1994) · Journal of Natural Products · doi:10.1021/np50113a024 · Cited by 44

Trachycladindoles A–G: cytotoxic heterocycles from an Australian marine sponge, Trachycladus laevispirulifer

Capon, R. J., Peng, C., & Dooms, C. (2008) · Organic & Biomolecular Chemistry · doi:10.1039/b803455a · Cited by 44

Bioactive Isoquinolinequinone Alkaloids from the South China Sea Nudibranch Jorunna Funebris and Its Sponge-Prey Xestospongia Sp.

Huang, R.-Y., Chen, W., Kurtán, T., et al. (2015) · Future Medicinal Chemistry · doi:10.4155/fmc.15.169 · Cited by 44

Araguspongine C Induces Autophagic Death in Breast Cancer Cells through Suppression of c-Met and HER2 Receptor Tyrosine Kinase Signaling

Akl, M. A., Ayoub, N. M., Ebrahim, H. Y., Mohyeldin, M. M., Orabi, K. Y., Foudah, A. I., & Sayed, K. A. E. (2015) · Marine Drugs · doi:10.3390/md13010288 · Cited by 42

Novel Cytotoxic Oxygenated C29 Sterols from the Colombian Marine Sponge Polymastia tenax

Santafé, G., Paz, V., Rodrı́guez, J., et al. (2002) · Journal of Natural Products · doi:10.1021/np0200459 · Cited by 42

Chondropsins A and B: Novel Tumor Cell Growth-Inhibitory Macrolide Lactams from the Marine Sponge Chondropsis sp

Cantrell, C. L., Gustafson, K. R., Cecere, M. R., et al. (2000) · Journal of the American Chemical Society · doi:10.1021/ja0010711 · Cited by 42

A new sterol sulfate, Sch 572423, from a marine sponge, Topsentia sp.

Yang, S., Buivich, A., Chan, T., et al. (2003) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(03)00260-9 · Cited by 42

Phorbaketal A, Isolated from the Marine Sponge Phorbas sp., Exerts Its Anti-Inflammatory Effects via NF-κB Inhibition and Heme Oxygenase-1 Activation in Lipopolysaccharide-Stimulated Macrophages

Seo, Y.-J., Lee, K., Rho, J., & Choi, J. (2015) · Marine Drugs · doi:10.3390/md13117005 · Cited by 42

Naturally Occurring Somatostatin and Vasoactive Intestinal Peptide Inhibitors. Isolation of Alkaloids from Two Marine Sponges

Vassas, A., Bourdy, G., Paillard, J.-J., et al. (1996) · Planta Medica · doi:10.1055/s-2006-957790 · Cited by 41

Eurysterols A and B, Cytotoxic and Antifungal Steroidal Sulfates from a Marine Sponge of the Genus Euryspongia

Boonlarppradab, C., & Faulkner, D. J. (2007) · Journal of Natural Products · doi:10.1021/np060472c · Cited by 41

Adding lomustine to idarubicin and cytarabine for induction chemotherapy in older patients with acute myeloid leukemia: the BGMT 95 trial results

Pigneux, A., Perreau, V., Jourdan, É., et al. (2007) · Haematologica · doi:10.3324/haematol.11068 · Cited by 41

Plakortides I–L, four new cyclic peroxides from an undescribed Jamaican sponge Plakortis sp. (Homosclerophorida, Plakinidae)

Hu, J., Gao, H.-F., Kelly, M., et al. (2001) · Tetrahedron · doi:10.1016/s0040-4020(01)00947-4 · Cited by 41

Structure–activity relationship study on 13-deoxytedanolide, a highly antitumor macrolide from the marine sponge Mycale adhaerens

Nishimura, S., Matsunaga, S., Yoshida, S., et al. (2004) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2004.10.014 · Cited by 41

Autophagy-Modulating Aminosteroids Isolated from the Sponge Cliona celata

Keyzers, R. A., Daoust, J., Davies‐Coleman, M. T., et al. (2008) · Organic Letters · doi:10.1021/ol800937u · Cited by 41

Halicylindramides D and E, Antifungal Peptides from the Marine Sponge Halichondria cylindrata

Li, H., Matsunaga, S., & Fusetani, N. (1996) · Journal of Natural Products · doi:10.1021/np9600309 · Cited by 40

Orostanal, a novel abeo-sterol inducing apoptosis in leukemia cell from a marine sponge, Stelletta hiwasaensis

Miyamoto, T., Kodama, K., Aramaki, Y., et al. (2001) · Tetrahedron Letters · doi:10.1016/s0040-4039(01)01278-3 · Cited by 40

Isolation and Cytotoxic Evaluation of Marine Sponge-Derived Norterpene Peroxides

Sperry, S., Valeriote, F. A., Corbett, T. H., et al. (1998) · Journal of Natural Products · doi:10.1021/np970467w · Cited by 40

Polyoxygenated Dysidea Sterols That Inhibit the Binding of [I125] IL-8 to the Human Recombinant IL-8 Receptor Type A

Leone, P. D. A., Redburn, J., Hooper, J. N. A., et al. (2000) · Journal of Natural Products · doi:10.1021/np9904657 · Cited by 39

Novel sesterterpenoid and norsesterterpenoid RCE-protease inhibitors isolated from the marine sponge Hippospongia sp.

Craig, K. S., Williams, D. E. J., Hollander, I. J., et al. (2002) · Tetrahedron Letters · doi:10.1016/s0040-4039(02)00896-1 · Cited by 39

The marine sponge toxin agelasine B increases the intracellular Ca2+ concentration and induces apoptosis in human breast cancer cells (MCF-7)

Pimentel, A. A., Felibertt, P., Sojo, F. J., Colman, L., Mayora, A., Silva, M. L., Rojas, H., DiPolo, R., Suarez, A. I., Compagnone, R. S., et al. (2011) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-011-1677-x · Cited by 39

A Phase II Study of Halichondrin B Analog Eribulin Mesylate (E7389) in Patients with Advanced Non-small Cell Lung Cancer Previously Treated with a Taxane: A California Cancer Consortium Trial

Gitlitz, B. J., Tsao-Wei, D. D., Groshen, S. G., et al. (2011) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e31823f43ca · Cited by 39

The Nitrogenous Hamigerans: Unusual Amino Acid-Derivatized Aromatic Diterpenoid Metabolites from the New Zealand Marine Sponge Hamigera tarangaensis

Dattelbaum, J. D., Singh, A. J., Field, J. J., et al. (2014) · The Journal of Organic Chemistry · doi:10.1021/jo502370b · Cited by 39

Insight into Binding of Calyculin A to Protein Phosphatase 1

Wakimoto, T., Matsunaga, S., Takai, A., et al. (2002) · Chemistry & Biology · doi:10.1016/s1074-5521(02)00118-7 · Cited by 38

Bioactive Sesterterpenoids from a Korean Sponge Monanchora sp.

Wang, W., Mun, B., Lee, Y., et al. (2013) · Journal of Natural Products · doi:10.1021/np300573m · Cited by 38

Aragusterol B and D, new 26,27-cyclosterols from the Okinawan marine sponge of the genus Xestospongia

Iguchi, K., Shimura, H., Taira, S., et al. (1994) · The Journal of Organic Chemistry · doi:10.1021/jo00103a053 · Cited by 38

Aaptamines, marine spongean alkaloids, as anti-dormant mycobacterial substances

Arai, M., Han, C., Yamano, Y., Setiawan, A., & Kobayashi, M. (2014) · Journal of Natural Medicines · doi:10.1007/s11418-013-0811-y · Cited by 37

Topsentiasterol sulfates with novel iodinated and chlorinated side chains from the marine sponge Topsentia sp.

Guzii, A. G., Makarieva, T. N., Денисенко, В. А., et al. (2008) · Tetrahedron Letters · doi:10.1016/j.tetlet.2008.10.007 · Cited by 37

Antipodal Crambescin A2 Homologues from the Marine Sponge Pseudaxinella reticulata. Antifungal Structure–Activity Relationships

Jamison, M. T., & Molinski, T. F. (2015) · Journal of Natural Products · doi:10.1021/np501052a · Cited by 37

Crellastatin A: A Cytotoxic Bis-Steroid Sulfate from the Vanuatu Marine Sponge Crella sp.

D’Auria, M. V., Giannini, C., Zampella, A., et al. (1998) · The Journal of Organic Chemistry · doi:10.1021/jo981022v · Cited by 37

Strongylophorines, new protein tyrosine phosphatase 1B inhibitors, from the marine sponge Strongylophora strongilata collected at Iriomote Island

Lee, J., Abdjul, D. B., Yamazaki, H., et al. (2015) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2015.07.039 · Cited by 36

Investigation of the marine compound spongistatin 1 links the inhibition of PKCα translocation to nonmitotic effects of tubulin antagonism in angiogenesis

Rothmeier, A. S., Ischenko, I., Joore, J., Garczarczyk, D., Fürst, R., Bruns, C. J., Vollmar, A. M., & Zahler, S. (2008) · The FASEB Journal · doi:10.1096/fj.08-117127 · Cited by 36

New Cytotoxic Steroidal Alkaloids from the Philippine Sponge Corticium niger

Ridley, C. P., & Faulkner, D. J. (2003) · Journal of Natural Products · doi:10.1021/np0302706 · Cited by 36

New bioactive alkaloids from the marine sponge Stylissa sp.

Fouad, M. A., Debbab, A., Wray, V., et al. (2012) · Tetrahedron · doi:10.1016/j.tet.2012.09.097 · Cited by 36

Antifouling 26,27-Cyclosterols from the Vietnamese Marine Sponge Xestospongia testudinaria

Nguyen, X. C., Longeon, A., Pham, V. C., et al. (2013) · Journal of Natural Products · doi:10.1021/np400288j · Cited by 36

Spiculoic Acids A and B, New Polyketides Isolated from the Caribbean Marine Sponge Plakortis angulospiculatus

HUANG, X.-H., van Soest, R. W. M., Roberge, M., et al. (2003) · Organic Letters · doi:10.1021/ol0361047 · Cited by 36

Amaranzole A, a New N-Imidazolyl Steroid from Phorbas amaranthus

Morinaka, B. I., Masuno, M. N., Pawlik, J. R., et al. (2007) · Organic Letters · doi:10.1021/ol702325e · Cited by 35

Sesterterpenes from the Tropical Sponge Coscinoderma sp.

Bae, J., Jeon, J., Lee, Y., et al. (2011) · Journal of Natural Products · doi:10.1021/np200492k · Cited by 35

Polychlorinated Androstanes from the Burrowing Sponge Cliona nigricans

Fattorusso, E., Taglialatela‐Scafati, O., Petrucci, F., et al. (2004) · Organic Letters · doi:10.1021/ol049548r · Cited by 35

Isolation of dephosphonocalyculin a from the marine sponge, Discodermia calyx

Matsunaga, S., Wakimoto, T., Fusetani, N., et al. (1997) · Tetrahedron Letters · doi:10.1016/s0040-4039(97)00748-x · Cited by 34

Purpuroines A–J, halogenated alkaloids from the sponge Iotrochota purpurea with antibiotic activity and regulation of tyrosine kinases

Shen, S. H., Liu, D., Chen, D. W., et al. (2012) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2012.10.014 · Cited by 34

Antineoplastic Agents. 400. Synthesis of the Indian Ocean Marine Sponge Cyclic Heptapeptide Phakellistatin 2,1a

Pettit, G. R., Rhodes, M. R., & Tan, R. (1999) · Journal of Natural Products · doi:10.1021/np980168m · Cited by 34

Minor Steroidal Alkaloids from the Marine Sponge Corticium sp.

Borbone, N., Marino, S. D., Iorizzi, M., et al. (2002) · Journal of Natural Products · doi:10.1021/np020027r · Cited by 34

Mirabilin, an Antitumor Macrolide Lactam from the Marine Sponge Siliquariaspongia mirabilis

Plaza, A., Baker, H. L., & Bewley, C. A. (2008) · Journal of Natural Products · doi:10.1021/np070603p · Cited by 34

Participation of the β-hydroxyketone part for potent cytotoxicity of callystatin A, a spongean polyketide

Murakami, N., Sugimoto, M., & Kobayashi, M. (2001) · Bioorganic & Medicinal Chemistry · doi:10.1016/s0968-0896(00)00220-0 · Cited by 34

Scalarane Sesterterpenes from the Sponge Hyatella sp.

Jeon, J., Bae, J., Lee, K. J., et al. (2011) · Journal of Natural Products · doi:10.1021/np1006873 · Cited by 34

Phorone A and Isophorbasone A, Sesterterpenoids Isolated from the Marine Sponge Phorbas sp.

Wang, W., Lee, Y., Lee, T. G., et al. (2012) · Organic Letters · doi:10.1021/ol3019874 · Cited by 34

Chondropsin D, a New 37-Membered-Ring Macrolide Lactam from the Marine Sponge Chondropsis Species

Rashid, M. A., Cantrell, C. L., Gustafson, K. R., et al. (2001) · Journal of Natural Products · doi:10.1021/np0101907 · Cited by 33

Nagelamides U–W, bromopyrrole alkaloids from a marine sponge Agelas sp.

Tanaka, N., Kusama, T., Takahashi‐Nakaguchi, A., et al. (2013) · Tetrahedron Letters · doi:10.1016/j.tetlet.2013.05.023 · Cited by 33

Psammaplysenes C and D, Cytotoxic Alkaloids from Psammoclemma sp.

Buchanan, M. S., Carroll, A. R., Addepalli, R., et al. (2007) · Journal of Natural Products · doi:10.1021/np0703646 · Cited by 33

A One-Pot Synthesis and Biological Activity of Ageladine A and Analogues

Shengule, S. R., Loa-Kum-Cheung, W. L., Parish, C. R., Blairvacq, M., Meijer, L., Nakao, Y., & Karuso, P. (2011) · Journal of Medicinal Chemistry · doi:10.1021/jm200039m · Cited by 33

New Cytotoxic Steroids from the Indian Ocean Sponge Axinella cf. bidderi

Funel, C., Berrué, F., Roussakis, C., et al. (2004) · Journal of Natural Products · doi:10.1021/np034021t · Cited by 33

New Pentacyclic Compounds from the Okinawan Marine Sponge Xestospongia sapra

Kobayashi, J., Hirase, T., Shigemori, H., et al. (1992) · Journal of Natural Products · doi:10.1021/np50085a028 · Cited by 33

Heteroaromatic alkaloids, nakijinamines, from a sponge Suberites sp.

Takahashi, Y., Tanaka, N., Kubota, T., et al. (2012) · Tetrahedron · doi:10.1016/j.tet.2012.08.018 · Cited by 33

Phorbasones A and B, Sesterterpenoids Isolated from the Marine Sponge Phorbas sp. and Induction of Osteoblast Differentiation

Rho, J., Hwang, B. S., Joung, S., et al. (2011) · Organic Letters · doi:10.1021/ol1029386 · Cited by 33

Strongylophorines, meroditerpenoids from the marine sponge Petrosia corticata, function as proteasome inhibitors

Noda, A., Sakai, E., Kato, H., et al. (2015) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2015.04.075 · Cited by 33

Euryspongins A–C, three new unique sesquiterpenes from a marine sponge Euryspongia sp.

Yamazaki, H., Nakazawa, T., Sumilat, D. A., et al. (2013) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2013.01.102 · Cited by 33

Antichlamydial Sterol from the Red Sea Sponge Callyspongia aff. implexa

Abdelmohsen, U. R., Cheng, C., Reimer, A., et al. (2015) · Planta Medica · doi:10.1055/s-0035-1545721 · Cited by 33

Cytotoxic Scalarane Sesterterpenes from a Sponge, Hyrtios erecta

Tsuchiya, N., Sato, A., Hata, T., et al. (1998) · Journal of Natural Products · doi:10.1021/np970462z · Cited by 32

New chondropsin macrolide lactams from marine sponges in the genus Ircinia

Rashid, M. A., Gustafson, K. R., & Boyd, M. R. (2001) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)02348-0 · Cited by 32

Xestobergsterol C, a New Pentacyclic Steroid from the Okinawan Marine Sponge Ircinia sp. and Absolute Stereochemistry of Xestobergsterol A

Kobayashi, J., Shinonaga, H., Shigemori, H., et al. (1995) · Journal of Natural Products · doi:10.1021/np50116a029 · Cited by 32

Antineoplastic agents 315. Isolation and structure of the marine sponge cancer cell growth inhibitor phakellistatin 5

Pettit, G. R., Xu, J.-P., Cichacz, Z. A., Williams, M. D., Dorsaz, A.-C., Brune, D. C., Boyd, M. R., & Cerny, R. L. (1994) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(01)80108-6 · Cited by 32

Theopederins K and L. Highly Potent Cytotoxic Metabolites from a Marine Sponge Discodermia Species

Paul, G. K., Gunasekera, S. P., Longley, R. E., et al. (2001) · Journal of Natural Products · doi:10.1021/np0103766 · Cited by 32

Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells

Wilmes, A., O’Sullivan, D., Chan, A. H. L., Chandrahasen, C., Paterson, I., Northcote, P. T., Flamme, A. C. L., & Miller, J. H. (2010) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-010-1461-3 · Cited by 32

Phormidolides B and C, Cytotoxic Agents from the Sea: Enantioselective Synthesis of the Macrocyclic Core

Lorente, A., Gil, A., Fernández, R., et al. (2014) · Chemistry - A European Journal · doi:10.1002/chem.201404341 · Cited by 32

Isolation of a New Mycalolide from the Marine Sponge Mycale izuensis

Phuwapraisirisan, P., Matsunaga, S., van Soest, R. W. M., et al. (2002) · Journal of Natural Products · doi:10.1021/np010663+ · Cited by 32

Cinanthrenol A, an Estrogenic Steroid Containing Phenanthrene Nucleus, from a Marine Sponge Cinachyrella sp.

Machida, K., Abe, T., Arai, D., et al. (2014) · Organic Letters · doi:10.1021/ol5000023 · Cited by 31

Novel Bishomoscalarane Sesterterpenes from the Sponge Phyllospongia foliascens

Zeng, L., Fu, X., Su, J., et al. (1991) · Journal of Natural Products · doi:10.1021/np50074a012 · Cited by 31

Lehualides A−D, Metabolites from a Hawaiian Sponge of the Genus Plakortis

Sata, N., Abinsay, H., Yoshida, W. Y., et al. (2005) · Journal of Natural Products · doi:10.1021/np0500528 · Cited by 31

Topsentinols, 24-Isopropyl Steroids from the Marine Sponge Topsentia sp.

Dai, J., Sorribas, A., Yoshida, W. Y., Kelly, M., & Williams, P. G. (2010) · Journal of Natural Products · doi:10.1021/np100374b · Cited by 31

Isolation and Structure of Axinastatin 4 from the Western Indian Ocean Marine sponge Axinella cf. carteri

Pettit, G. R., Gao, F., & Cerny, R. L. (1993) · Heterocycles · doi:10.3987/com-93-s(t)137 · Cited by 31

25-Deoxycacospongionolide B and cacospongionolide C, two new terpenoids from the sponge Fasciospongia cavernosa

Rosa, S. D., Puliti, R., Crispino, A., et al. (1995) · Tetrahedron · doi:10.1016/0040-4020(95)00638-o · Cited by 31

A Bastadin with Potent and Selective δ-Opioid Receptor Binding Affinity from the Australian Sponge Ianthella flabelliformis

Carroll, A. R., Kaiser, S. M., Davis, R. A., et al. (2010) · Journal of Natural Products · doi:10.1021/np100010z · Cited by 30

Halichonadins G–J, new sesquiterpenoids from a sponge Halichondria sp.

Suto, S., Tanaka, N., Fromont, J., et al. (2011) · Tetrahedron Letters · doi:10.1016/j.tetlet.2011.04.105 · Cited by 30

A Phase II Study of Eribulin Mesylate (E7389) in Patients With Advanced, Previously Treated Non–Small-Cell Lung Cancer

Spira, A. I., Iannotti, N. O., Savin, M. A., Neubauer, M., Gabrail, N. Y., Yanagihara, R. H., Zang, E. A., Cole, P. E., Shuster, D. E., & Das, A. (2011) · Clinical Lung Cancer · doi:10.1016/j.cllc.2011.06.010 · Cited by 30

Kabiramides J and K, Trisoxazole Macrolides from the Sponge Pachastrissa nux

Sirirak, T., Kittiwisut, S., Janma, C., et al. (2011) · Journal of Natural Products · doi:10.1021/np100886y · Cited by 30

New Candidaspongiolides, Tedanolide Analogues That Selectively Inhibit Melanoma Cell Growth

Whitson, E. L., Pluchino, K. M., Hall, M. D., et al. (2011) · Organic Letters · doi:10.1021/ol201329p · Cited by 29

Solomonsterol A, a Marine Pregnane-X-Receptor Agonist, Attenuates Inflammation and Immune Dysfunction in a Mouse Model of Arthritis

Mencarelli, A., D’Amore, C., Renga, B., et al. (2013) · Marine Drugs · doi:10.3390/md12010036 · Cited by 29

Franklinolides A–C from an Australian Marine Sponge Complex: Phosphodiesters Strongly Enhance Polyketide Cytotoxicity

Zhang, H., Conte, M. M., & Capon, R. J. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201005883 · Cited by 29

Isolation and Structure of the Human Cancer Cell Growth Inhibitory Phakellostatin 4 from the Western Pacific Sponge Phakellia Costata

Pettit, G. R., Xu, J.-P., Cichacz, Z. A., et al. (1995) · Heterocycles · doi:10.3987/com-94-s45 · Cited by 28

Fibrosterol Sulfates from the Philippine Sponge Lissodendoryx ( Acanthodoryx) fibrosa : Sterol Dimers that Inhibit PKCζ

Whitson, E. L., Bugni, T. S., Chockalingam, P. S., et al. (2009) · The Journal of Organic Chemistry · doi:10.1021/jo900844r · Cited by 28

Structural Variations to the 9-N-Methyladeninium Diterpenoid Hybrid Commonly Isolated from Agelas Sponges

Calcul, L., Tenney, K., Ratnam, J., et al. (2010) · Australian Journal of Chemistry · doi:10.1071/ch10036 · Cited by 28

A phase 1b/2 study of vosaroxin in combination with cytarabine in patients with relapsed or refractory acute myeloid leukemia

Lancet, J. E., Roboz, G. J., Cripe, L. D., et al. (2014) · Haematologica · doi:10.3324/haematol.2014.114769 · Cited by 28

Scalarane sesterterpenes from the Egyptian Red Sea sponge Phyllospongia lamellosa

Hassan, M. H. A., Rateb, M. E., Hetta, M. H., et al. (2014) · Tetrahedron · doi:10.1016/j.tet.2014.12.035 · Cited by 28

Pentacyclic Ingamine Alkaloids, a New Antiplasmodial Pharmacophore from the Marine Sponge Petrosid Ng5 Sp5

Ilias, M., Ibrahim, M. A., Khan, S. I., Jacob, M. R., Tekwani, B. L., Walker, L., & Samoylenko, V. (2012) · Planta Medica · doi:10.1055/s-0032-1315213 · Cited by 28

Structural Assignment of Poecillastrins B and C, Macrolide Lactams from the Deep-Water Caribbean Sponge Poecillastra Species

Takada, K., Choi, B. W., Rashid, M. A., et al. (2006) · Journal of Natural Products · doi:10.1021/np0604984 · Cited by 27

Isolation and X-ray crystal structure of racemic Xestospongin D from the Singapore marine sponge Niphates sp1

Pettit, G. R., Orr, B., Herald, D. L., et al. (1996) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/0960-894x(96)00225-9 · Cited by 27

Induction of apoptosis in endometrial cancer cells by psammaplysene A involves FOXO1

Berry, E., Hardt, J. L., Clardy, J., et al. (2008) · Gynecologic Oncology · doi:10.1016/j.ygyno.2008.10.017 · Cited by 27

8-Isocyanoamphilecta-11(20),15-diene, a new antimalarial isonitrile diterpene from the sponge Ciocalapata sp.

Wattanapiromsakul, C., Chanthathamrongsiri, N., Bussarawit, S., et al. (2009) · Canadian Journal of Chemistry · doi:10.1139/v09-030 · Cited by 27

Densanins A and B, New Macrocyclic Pyrrole Alkaloids Isolated from the Marine Sponge Haliclona densaspicula

Hwang, B. S., Oh, J. S., Jeong, E. J., et al. (2012) · Organic Letters · doi:10.1021/ol3028303 · Cited by 27

Unusual polyoxygenated sterols from a Philippines sponge Xestospongia sp.

Lerch, M. L., & Faulkner, D. J. (2001) · Tetrahedron · doi:10.1016/s0040-4020(01)00296-4 · Cited by 27

Anti-inflammatory cyclopeptides from the marine sponge Theonella swinhoei

Festa, C., Marino, S. D., D’Auria, M. V., et al. (2012) · Tetrahedron · doi:10.1016/j.tet.2012.01.097 · Cited by 26

Aragusterol C: A novel halogenated marine steroid from an Okinawan sponge,Xestospongia sp., possessing potent antitumor activity

Shimura, H., IGUCHI, K., Yamada, Y., et al. (1994) · Cellular and Molecular Life Sciences · doi:10.1007/bf01984951 · Cited by 26

New cytotoxic spongian diterpenes from the sponge Dysidea cf. arenaria

Agena, M., Tanaka, C., Hanif, N., et al. (2008) · Tetrahedron · doi:10.1016/j.tet.2008.11.101 · Cited by 26

Peloruside A Inhibits Growth of Human Lung and Breast Tumor Xenografts in an Athymic nu/nu Mouse Model

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Scalarane sesterterpenes from Thorectidae sponges as inhibitors of TDP-43 nuclear factor

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Koshikamide A2, a Cytotoxic Linear Undecapeptide Isolated from a Marine Sponge ofTheonellasp.

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Steroids from an Australian Sponge Psammoclema sp.

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Njaoaminiums A, B, and C: Cyclic 3-Alkylpyridinium Salts from the Marine Sponge Reniera sp.

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Disturbance of voltage-induced cellular calcium entry by marine dimeric and tetrameric pyrrole–imidazole alkaloids

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New pentacyclic polyketide dimeric peroxides from a Taiwanese marine sponge Petrosia elastica

Shen, Y. C., Prakash, C. V. S., & Guh, J. (2004) · Tetrahedron Letters · doi:10.1016/j.tetlet.2004.01.029 · Cited by 17

The mode of rabbit platelet shape change and aggregation induced by theonezolide-A, a novel polyketide macrolide, isolated from the Okinawan marine spongeTheonellasp.

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Gelliusterols A−D, New Acetylenic Sterols from a Sponge, Gellius Species

Gallimore, W. A., Kelly, M., & Scheuer, P. J. (2001) · Journal of Natural Products · doi:10.1021/np000585a · Cited by 16

A New Cytotoxic Sterol Methoxymethyl Ether from a Deep Water Marine Sponge Scleritoderma sp. cf. paccardi

Gunasekera, S. P., Kelly‐Borges, M., & Longley, R. E. (1996) · Journal of Natural Products · doi:10.1021/np9600311 · Cited by 16

Novel Cytotoxic Polyoxygenated Steroids from an Okinawan SpongeDysideasp.

Govindam, S. V. S., Choi, B., Yoshioka, Y., Kanamoto, A., Fujiwara, T., Okamoto, T., & Ojika, M. (2012) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.120017 · Cited by 16

A new cyclostellettamine from sponge Amphimedon compressa

Xu, N. J., Sun, X., & Yan, X. J. (2007) · Chinese Chemical Letters · doi:10.1016/j.cclet.2007.06.006 · Cited by 15

A new cytotoxic cholesterol sulfate from marine spongeHalichondria rugosa

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New cytotoxic spongian-class rearranged diterpenes from a marine sponge

Uddin, M. H., Hossain, M. K., Nigar, M., et al. (2012) · Chemistry of Natural Compounds · doi:10.1007/s10600-012-0262-9 · Cited by 15

Manzamenones L–N, new dimeric fatty-acid derivatives from an Okinawan marine sponge Plakortis sp.

Kubota, T., Ishiguro, Y., Takahashi‐Nakaguchi, A., et al. (2012) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2012.10.109 · Cited by 15

The mode of rabbit platelet shape change and aggregation induced by theonezolide-A, a novel polyketide macrolide, isolated from the Okinawan marine sponge Theonella sp.

Rho, M., Park, Y.-H., Sasaki, S., et al. (1996) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-74-2-193 · Cited by 14

New Bioactive Bromotyrosine-Derived Alkaloid from a Marine Sponge Aplysinella sp.

Ankudey, F., Kiprof, P., Stromquist, E., et al. (2008) · Planta Medica · doi:10.1055/s-2008-1074506 · Cited by 13

Shishicrellastatins, inhibitors of cathepsin B, from the marine sponge Crella (Yvesia) spinulata

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Thein vivoanti-plasmodial activity of haliclonacyclamine A, an alkaloid from the marine sponge,Haliclonasp.

Mani, L., Petek, S., Valentin, A., et al. (2011) · Natural Product Research · doi:10.1080/14786419.2010.547858 · Cited by 12

Lehualides E−K, Cytotoxic Metabolites from the Tongan Marine Sponge Plakortis sp.

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Three new aaptamine derivatives from the South China Sea sponge Aaptos aaptos

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New Indole Alkaloids from the Sponge Plakortis sp.

Hanif, N., Yamada, K., Kitamura, M., et al. (2015) · Chemistry of Natural Compounds · doi:10.1007/s10600-015-1508-0 · Cited by 10

New 9,11-Secosterol From the Tyrrhenian Sponge Fasciospongia Cavernosa

Rosa, S. D., Giulio, A. D., Crisping, A., et al. (1999) · Natural product letters · doi:10.1080/10575639908048485 · Cited by 7

N -Containing Metabolites from the Marine Sponge Agelas clathrodes

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Mobilité conformationnelle et migration des liaisonsπ dans le [24]annulène

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Allos-hemicalyculin A, a photochemically converted calyculin from the marine sponge Discodermia calyx

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Cytotoxic Polyketides from the Marine Sponge Discodermia calyx

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ChemInform Abstract: Leucascandrolide B, a New 16‐Membered, Extensively Methyl‐Branched Polyoxygenated Macrolide from the Calcareous Sponge Leucascandra caveolata from Northeastern Waters of New Caledonia.

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Corrigendum to : Structural Variations to the 9- N -Methyladeninium Diterpenoid Hybrid Commonly Isolated from Agelas Sponges

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ChemInform Abstract: Absolute Stereostructure of Swinholide A (I), a Potent Cytotoxic Macrolide from the Okinawan Marine Sponge Theonella swinhoei

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Marine Natural Products: A Source of Novel Anticancer Drugs

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Sponge (2′,5′)oligoadenylate synthetase activity in the whole sponge organism and in a primary cell culture

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ChemInform Abstract: Hippolachnin A, a New Antifungal Polyketide from the South China Sea Sponge Hippospongia lachne.

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Detection of pharmacologically active natural products using ecology. Selected examples from Indopacific marine invertebrates and sponge-derived fungi

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Minor and trace sterols from marine invertebrates 56. Novel coprostanols from the marine sponge petrosia ficiformis

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