Prevalence of coronary heart disease, left ventricular failure and hypertension in middle-aged, newly diagnosed Type 2 (non-insulin-dependent) diabetic subjects
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The prevalence of coronary heart disease, left ventricular failure and hypertension was examined in a representative group of 133 newly diagnosed Type 2 (non-insulin-dependent) diabetic subjects (70 men, 63 women), aged 45 to 64 years, and in a group of 144 randomly selected non-diabetic control subjects (62 men, 82 women) of the same age group. The prevalence of previous myocardial infarction (major Q-QS abnormalities in resting ECG and/or myocardial infarction verified at hospital) was increased 1.7-fold in male (NS) and 4.4-fold in female (p = 0.007) diabetic patients compared with that found in non-diabetic subjects. Chest pain symptoms and ischaemic ECG abnormalities were about twice as common among diabetic than among non-diabetic subjects. The frequency of coronary heart disease defined by chest pain symptoms and ECG abnormalities was 3.5 times higher in male (p = 0.001) and 3.1 times higher in female (p = 0.001) diabetic patients than in the respective non-diabetic subjects. The frequency of current digitalis therapy was increased 3.3-fold in male (p = 0.006) and 3.9-fold in female (p = 0.001) diabetic patients suggesting an increased frequency of left ventricular failure among diabetic subjects. The prevalence of hypertension, based on the elevated blood pressure levels and/or current use of antihypertensive drugs, was increased 1.6-1.7-fold among the diabetic patients.
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References 39 · Cited by 165
Research works printed but not linked: 1
- [23]23. M.D. academic thesis. University of Kuopio 1983
- Authors
- Uusitupa, M., Siitonen, O., Aro, A., & Py�r�l�, K.
- Affiliations
- Kuopio University Hospital (FI)
- ORCID
- Uusitupa, M.
- Venue
- Diabetologia
- Published
- 1985-01
- Volume
- 28
- Issue
- 1
- Pages
- 22-27
- ISSN
- 0012-186X (ISSN-L)
- 1432-0428
- OpenAlex
- W2075226613
- Semantic Scholar
- 7b9a009ac2d9a8913d7ed0217c0dcfafa0472958
- Cited by
- 165
- References
- 39
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 3 · 2021: 2 · 2018: 3 · 2015: 4 · 2014: 2 · 2012: 1
- FWCI
- 5.28
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Diabetologia (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Academy of Finland
- Medical Research Council
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- type 2 diabetes, coronary artery disease, left ventricular failure, hypertension, myocardial infarction, chest pain, electrocardiographic abnormalities, digitalis therapy, middle-aged adults, sex differences, cardiovascular comorbidity
- MeSH terms
- Body Weight, Coronary Disease, Diabetes Mellitus, Type 2, Digitalis Glycosides, Female, Heart Diseases, Heart Ventricles, Humans, Hypertension, Male, Middle Aged
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