Disproportionate elevation of immunoreactive proinsulin in Type 2 (non-insulin-dependent) diabetes mellitus and in experimental insulin resistance

Ward, W. K., LaCava, E. C., Paquette, T. L., Beard, J. C., Wallum, B. J., Porte, D.·1987·Diabetologia

DOI 10.1007/bf00296991

Cited by (275)

Items 101–200 of 275

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Measurement of Pro-Islet Amyloid Polypeptide (1–48) in Diabetes and Islet Transplants
Jaques A. Courtade, Agnieszka M. Klimek-Abercrombie, Yi‐Chun Chen, Nirja Patel, Phoebe Y. T. Lu, Cate Speake, Paul C. Orban, Behzad Najafian, Graydon S. Meneilly, Carla J. Greenbaum et al. · 2017 · The Journal of Clinical Endocrinology & Metabolism
Relative Hyperproinsulinemia as a Sign of Islet Dysfunction in Women with Impaired Glucose Tolerance1
Hillevi Larsson, Bo Åhrén · 1999 · The Journal of Clinical Endocrinology & Metabolism
Basal and dynamic proinsulin-insulin relationship to assess β-cell function during OGTT in metabolic disorders
Andrea Tura, Giovanni Pacini, Alexandra Kautzky‐Willer, Bernhard H. Ludvik, Rudolf Prager, Karl Thomaseth · 2003 · American Journal of Physiology-Endocrinology and Metabolism
Prolonged Exposure of Human β-Cells to High Glucose Increases Their Release of Proinsulin during Acute Stimulation with Glucose or Arginine1
Katleen Hostens, Zhidong Ling, Christiaan F. H. Van Schravendijk, DANIEL G. PIPELEERS · 1999 · The Journal of Clinical Endocrinology & Metabolism
Normal hepatic insulin sensitivity in lean, mild noninsulin-dependent diabetic patients
Jan Pigon, Adria Giacca, C. G. Östenson, Loretta Lam, M. Vranić, Suad Efendić · 1996 · The Journal of Clinical Endocrinology & Metabolism
Immunoradiometric assay of insulin, intact proinsulin and 32–33 split proinsulin and radioimmunoassay of insulin in diet-treated Type 2 (non-insulin-dependent) diabetic subjects
PENELOPE M. S. CLARK, J Lévy, Lorna Cox, Melanie A. Burnett, R. C. Turner, Charles Nicholas Hales · 1992 · Diabetologia
Effects of Immunosuppressive Agents on Glucose Metabolism
Andrew J. Krentz, Jan Dmitrewski, David A. Mayer, M. Nattrass · 1995 · BioDrugs
Proinsulin processing in the diabetic Goto-Kakizaki rat
Paul C. Guest, SM Abdel-Halim, D Gross, Anne Clark, Vincent Poitout, Rodabe Navroze Amaria, CG Ostenson, JC Hutton · 2002 · Journal of Endocrinology
PPARγ agonists in type 2 diabetes: how far have we come in ‘preventing the inevitable’? A review of the metabolic effects of rosiglitazone
Bernard Zinman · 2001 · Diabetes Obesity and Metabolism
Effect of insulin resistance and hyperglycemia on proinsulin release in a primate model of diabetes mellitus
Steven E. Kahn, D. K. McCulloch, Michael W. Schwartz, JL Palmer, Daniel Porte · 1992 · The Journal of Clinical Endocrinology & Metabolism
Rapid Deterioration of Insulin Secretion in Obese Adolescents Preceding the Onset of Type 2 Diabetes
Deborah A. Elder, Lindsey N. Hornung, Patricia M. Herbers, Ron L. Prigeon, Jessica Graus Woo, David A. D’Alessio · 2014 · The Journal of Pediatrics
Characterization of Antibodies to Products of Proinsulin Processing Using Immunofluorescence Staining of Pancreas in Multiple Species
Ali Asadi, Jennifer E. Bruin, Timothy J. Kieffer · 2015 · Journal of Histochemistry & Cytochemistry
The Diagnosis of Fasting Hypoglycemia Due to an Islet-Cell Tumor Obscured by a Highly Specific Insulin Assay
Chee W. Chia, Christopher D. Saudek · 2003 · The Journal of Clinical Endocrinology & Metabolism
Increased susceptibility of islets from diabetes-prone Psammomys obesus to the deleterious effects of chronic glucose exposure
D J Gross, Gil Leibowitz, Erol Cerasi, Ν. Kaiser · 1996 · Endocrinology
Epidemiology of hypertension and insulin resistance syndrome
Steven M. Haffner · 1997 · Journal of Hypertension
Pancreatic beta-cell function and glucose metabolism in human segmental pancreas and kidney transplantation
Erik Christiansen, H. B. Andersen, Kirstine K. Rasmussen, Niels Juel Christensen, Klaus Ølgaard, Preben Olund Kirkegaard, B. Tronier, Aage Vølund, Peter Damsbo, F Burcharth et al. · 1993 · American Journal of Physiology-Endocrinology and Metabolism
Circulating proinsulinlike molecules
John S Yudkin · 1993 · Journal of Diabetes and its Complications
The β-cell glucose toxicity hypothesis: Attractive but difficult to prove
Gordon C. Weir, Peter C. Butler, Susan Bonner‐Weir · 2021 · Metabolism
Do High Proinsulin and C-Peptide Levels Play a Role in Autonomic Nervous Dysfunction?
Jari P. Töyry, LEO K. NISKANEN, Matti Mäntysaari, Esko Länsimies, Steven M. Haffner, Heikki Miettinen, Matti I.J. Uusitupa · 1997 · Circulation
Effects of carbohydrate restriction on postprandial glucose metabolism, β-cell function, gut hormone secretion, and satiety in patients with Type 2 diabetes
Mads Juul Skytte, Amirsalar Samkani, Arne Vernon Astrup, Jan Frystyk, Jens Frederik Rehfeld, Jens Juul Holst, Sten Madsbad, Keith Burling, Mogens Fenger, Mads Norvin Thomsen et al. · 2020 · American Journal of Physiology-Endocrinology and Metabolism
Proinsulin and insulin concentrations following intravenous glucose challenges in normal, obese, and non-insulin-dependent diabetic subjects
Stephen N. Davis, PierMarco Piatti, L. Monti, M. D. Brown, W J Branch, Charles Nicholas Hales, K.George M.M. Alberti · 1993 · Metabolism
Hyperproinsulinemia in the diabetic Psammomys obesus is a result of increased secretory demand on the beta-cell
Michal Gadot, Yafa Ariav, E Cerasi, Ν. Kaiser, D J Gross · 1995 · Endocrinology
Hyperinsulinaemia in obesity is not accompanied by an increase in serum proinsulin/insulin ratio in groups of human subjects with and without glucose intolerance
Ikuo Shiraishi, Yasuhiko Iwamoto, Takeshi Kuzuya, Ayako Matsuda, Shinobu Kumakura · 1991 · Diabetologia
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Sakina H. Bharmal, Sayali A. Pendharkar, Ruma G. Singh, Mark O. Goodarzi, Stephen Jacob Pandol, Maxim S. Petrov · 2017 · Pancreatology
Cardiovascular Risk Factors and the Prediabetic Syndrome
Steven M. Haffner · 1996 · Annals of Medicine
Postprandial Triglyceride High Response and the Metabolic Syndromea
Jürgen Schrezenmeir, Stephanie Fenselau, I. Keppler, J. ABEL, B. Orth, C. Laue, W. STÜRMER, U. Fauth, Miklos P.B. Halmagyi, Winfried März · 1997 · Annals of the New York Academy of Sciences
Possible Risk Factors of Carotid Artery Atherosclerosis in the Japanese Population. A Primary Prevention Study in Non-diabetic Subjects.
Masahiko Okada, Takashi Miida, Hitoshi Hama, Shogo Yata, Takao SUNAGA, Akiko Tsuda, Hisashi Saitō · 2000 · Internal Medicine
Leptin concentrations are associated with higher proinsulin and insulin concentrations but a lower proinsulin/insulin ratio in non-diabetic subjects
SM Haffner, Heikki Miettinen, Leena Moilanen Mykkänen, Michael P. Stern M. D · 1998 · International Journal of Obesity
Effect of Pioglitazone on Blood Proinsulin Levels in Patients with Type 2 Diabetes Mellitus.
Keiji Kubo · 2002 · Endocrine Journal
First direct assay for intact human proinsulin
Paule Houssa, Bo Dinesen, Michelle A. Deberg, Bruce H. Frank, Chris Van Schravendijk, F. Sodoyez‐Goffaux, Jean Claude Sodoyez · 1998 · Clinical Chemistry
Determinants of coronary vascular disease in patients with type ii diabetes mellitus and their therapeutic implications
David J. Schneider, Burton E. Sobel · 1997 · Clinical Cardiology
Insulin resistance in non-insulin-dependent diabetes mellitus
Aus Alzaid · 1996 · Acta Diabetologica
Serum Insulin , Proinsulin and Proinsulin / Insulin Ratio in Type 2 Diabetic Patients : As an Index of β - Cell Function or Insulin Resistance
Nan Hee Kim, D. L. Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi · 2000 · The Korean Journal of Internal Medicine
Glycaemic and nonglycaemic effects of pioglitazone in triple oral therapy of patients with type 2 diabetes
Mozhgan Dorkhan, Martin Magnusson, Anders H. Frid, ANDERS O. GRUBB, Leif Groop, Stefan V. Jovinge · 2006 · Journal of Internal Medicine
The Ability of Insulin To Inhibit the Formation of Amyloid by Pro-Islet Amyloid Polypeptide Processing Intermediates Is Significantly Reduced in the Presence of Sulfated Glycosaminoglycans
Hui Wang, Daniel P. Raleigh · 2014 · Biochemistry
Is aggregated IAPP a cause of beta-cell failure in transplanted human pancreatic islets?
Per Westermark, Arne Andersson, Gunilla Torstensdotter Westermark · 2005 · Current Diabetes Reports
Impaired Processing of Human Pro-Islet Amyloid Polypeptide Is Not a Causative Factor for Fibril Formation or Membrane Damage in Vitro
Lucie Khemtémourian, Gemma Lahoz Casarramona, Dennis P. L. Suylen, Tilman M. Hackeng, Johannes D. Meeldijk, Ben DE KRUIJFF, Jo W.M. Höppener, J. Antoinette Killian · 2009 · Biochemistry
Hormonal responses and future treatment of non‐insulin‐dependent diabetes mellitus (NIDDM)*
Suad Efendić, C-G Östenson · 1993 · Journal of Internal Medicine
Altered proinsulin conversion in rat pancreatic islets exposed long-term to various glucose concentrations or interleukin-1β
Andreas Börjesson, Carina Carlsson · 2007 · Journal of Endocrinology
Abnormalities in fasting circulating proinsulin concentration in mild gestational diabetes
Anne Dornhorst, M. Davies, V. Anyaoku, S. Hampton, Robert S Elkeles, Richard W. Beard, D. G. Johnston · 1991 · Clinical Endocrinology
Evidence against a Rate-Limiting Role of Proinsulin Processing for Maximal Insulin Secretion in Subjects with Impaired Glucose Tolerance and β-Cell Dysfunction1
Michael Stümvoll, Andreas Fritsche, Norbert Stefan, E. Hardt, Hans Ulrich Häring · 2001 · The Journal of Clinical Endocrinology & Metabolism
Hyperproinsulinemia and Proinsulin-to-Insulin Ratios in Swedish Middle-aged Men: Association with Glycemia and Insulin Resistance but Not with Family History of Diabetes
Valdemar Grill · 2002 · American Journal of Epidemiology
2 Hepatic glucose metabolism and insulin resistance in NIDDM and obesity
Eugene J. Barrett, Zhenqi Liu · 1993 · Baillière s Clinical Endocrinology and Metabolism
Impaired Proinsulin Processing is a Characteristic of Transplanted Islets
Agnieszka M. Klimek-Abercrombie, Galina Soukhatcheva, David M Thompson, Garth L. Warnock, Marzieh Salehi, Horacio Rilo, DL DAlessio, Graydon S. Meneilly, Constadina Panagiotopoulos, C. Bruce Verchere · 2009 · American Journal of Transplantation
Chronic Sulfonylurea Treatment and Hyperglycemia Aggravate Disproportionately Elevated Plasma Proinsulin Levels in Patients with Type 2 Diabetes.
Toyoshi Inoguchi, Fumio Umeda, MAIKO KAKIMOTO, Yasuhiro Sako, Hidehiro Ishii, KATSUMI NODA, Makoto Kunisaki, Minako Imamura, HM-YAN YU, Takashi Etoh et al. · 2000 · Endocrine Journal
Up-regulation of PAI-1 synthesis by insulin and proinsulin in HEP G2 cells but not in endothelial cells
Marie‐Christine Alessi, Francine J. Anfosso, Mireille Henry, Franck Peiretti, Gilles Nalbone, Irène Juhan-Vague · 1995 · Fibrinolysis and Proteolysis
Extensive amyloid formation in transplanted microencapsulated mouse and human islets
S. Bohman, G. Westermark · 2012 · Amyloid: Journal of Protein Folding Disorders
The serum levels of proinsulin and their relationship with IGFBP‐1 in obese children
Tomohiro Kamoda, H. Saitoh, Michiharu Inudoh, Kunihiko Miyazaki, Akira Matsui · 2005 · Diabetes Obesity and Metabolism
Loss of prohormone convertase 2 promotes beta cell dysfunction in a rodent transplant model expressing human pro-islet amyloid polypeptide
Jaques A. Courtade, Evan Y. Wang, Paul Yen, Derek L. Dai, Galina Soukhatcheva, Paul C. Orban, C. Bruce Verchere · 2016 · Diabetologia
Are specific serum insulin levels low in impaired glucose tolerance and type II diabetes?: Measurement with a radioimmunoassay blind to proinsulin, in the population of Wadena, Minnesota
F. C. Goetz, Lindsey French, William T. B. Thomas, Ronald L. Gingerich, J.P. Clements · 1995 · Metabolism
Insulin resistance, insulin, proinsulin, and ambulatory blood pressure in type II diabetes.
Jonathan H. Pinkney, Vidya Mohamed‐Ali, A. E. Denver, C Foster, Mike Sampson, John S Yudkin · 1994 · Hypertension
Pantoprazole may improve beta cell function and diabetes mellitus
F. Inci, Murat Atmaca, Mustafa Öztürk, Saliha Yıldız, Ruşen Köçeroğlu, Ramazan Şekeroğlu, Süleyman Hilmi İpekçi, Levent Kebapçılar · 2014 · Journal of Endocrinological Investigation
Proinsulin and the proinsulin/insulin ratio in overweight and obese children and adolescents: relation to clinical parameters, insulin resistance, and impaired glucose regulation
Carlotta von Berghes, Georg E. Brabant, Heike Biebermann, Heiko Krude, Susanna Wiegand · 2011 · Pediatric Diabetes
Long-term in vitro exposure to high glucose increases proinsulin-like-molecules release by isolated human islets
Federico Bertuzzi, Katia Saccomanno, CARLO SOCCI, A. M. Davalli, M. V. Taglietti, C. Berra, E Dalcin, L. Monti, Guido Pozza, A. E. Pontiroli · 1998 · Journal of Endocrinology
Pharmacodynamics and pharmacokinetics of intravenous glibenclamide in Caucasian and Chinese patients with type-2 diabetes
A. Jönsson, Juliana C.N. Chan, Tony Rydberg, Stein Vaaler, Bengt Hallengren, Clive Stewart Cockram, Julia Critchley, Arne Melander · 2000 · European Journal of Clinical Pharmacology
Specific insulin and proinsulin concentrations in nondiabetic South Indians
Chamukuttan Snehalatha, Ambady Ramachandran, K. Satyavani, Vijay Viswanathan, Steven M. Haffner · 1998 · Metabolism
Progress in Population Analyses of the Insulin Resistance Syndrome
Steven M. Haffner · 1997 · Annals of the New York Academy of Sciences
Diabetes and Thrombosis
David J. Schneider, Burton E. Sobel · 2005 · Humana Press eBooks
Association of the mutation for the human carboxypeptidase E gene exon 4 with the severity of coronary artery atherosclerosis
En‐Zhi Jia, Jie Wang, Zhijian Yang, Tiebing Zhu, Liansheng Wang, Hui Wang, Chunjian Li, Bo Chen, Kejiang Cao, Jun Huang et al. · 2007 · Molecular Biology Reports
Effects of Pioglitazone in Combination with Metformin or a Sulfonylurea Compared to a Fixed-Dose Combination of Metformin and Glibenclamide in Patients with Type 2 Diabetes
Marco Comaschi, A. Demicheli, C. Di Pietro, A. Bellatreccia, Segundo Mariz, the COM06 Study Investigators · 2007 · Diabetes Technology & Therapeutics
The contribution of proinsulin and des-31,32 proinsulin to the hyperinsulinemia of diabetic and nondiabetic cirrhotic patients
Yolanta T. Kruszynska, David S. Harry, Vidya Mohamed‐Ali, Philip Home, John S Yudkin, Neil McIntyre · 1995 · Metabolism
Subtotal pancreatectomy for hypoglycemia due to congenital hyperinsulinism: long-term follow-up of neurodevelopmental and pancreatic function
Kristina I. Rother, Jane M. S. Matsumoto, Norman H. Rasmussen, W Frederick Schwenk · 2001 · Pediatric Diabetes
PROINSULIN, PROAMYLIN AND THE BETA CELL ENDOPLASMIC RETICULUM: THE KEY FOR THE PATHOGENESIS OF DIFFERENT DIABETES PHENOTYPES
Constantin Ionescu-Tirgoviste, Cristian Guja · 2007
Lifestyle Interventions and the Prevention and Treatment of Type 2 Diabetes
Mary Beth Weber, Jennifer G. Twombly, K.M. Venkat Narayan, Lawrence S. Phillips · 2010 · American Journal of Lifestyle Medicine
Pilot Study on the Effect of Orally Administered Bisphenol A on Glucose and Insulin Response in Nonobese Adults
Todd Alan Hagobian, Alyssa Bird, Sean T. Stanelle, Dana Williams, Andrew A. Schaffner, Suzanne Phelan · 2019 · Journal of the Endocrine Society
A sensitive and reliable method for assaying true human insulin without interaction with human proinsulin-like molecules
Lucilla Domenica Monti, Emilia P. Sandoli, V. C. Phan, PierMarco Piatti, Sabrina Costa, Antonio Secchi, Guido Pozza · 1995 · Acta Diabetologica
Increased secretion of 32,33 split proinsulin after intravenous glucose in glucose‐tolerant first‐degree relatives of patients with non‐insulin dependent diabetes of European, but not Asian, origin
Susan V. Gelding, C. Andres, Ratnam Niththyananthan, I. Peter Gray, H M Mather, D. O. Johnston · 1995 · Clinical Endocrinology
Insulin propeptides in conditions associated with insulin resistance in humans and their relevance to insulin measurements.
A. Proudler, I. Godsland, John C. Stevenson · 1994 · Metabolism: Clinical and Experimental
Abnormalities of intermediary metabolism following a gestational diabetic pregnancy
S. P. Chan, Susan V. Gelding, Richard J. McManus, J. S. D. Nlcholls, V. Anyaoku, R. Nlththyapanthan, Desmond G. Johnston, Anne Dornhorst · 1992 · Clinical Endocrinology
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Emily Kristen Sims, Grace Shin Hye Park, Kieren J. Mather, Raghavendra G. Mirmira, Ziyue Liu, Samir Kumar Gupta · 2018 · PLoS ONE
Non‐insulin dependent diabetes mellitus: defects in insulin secretion
Bruce H. R. Wolffenbuttel, Timon W. van Haeften · 1993 · European Journal of Clinical Investigation
Increased Molar Proinsulin-to-Insulin Ratio in Women With Previous Gestational Diabetes Does Not Predict Later Impairment of Glucose Tolerance
Ulf Hanson, Bengt Persson, SVEND G. HARTLING, Christian Binder · 1996 · Diabetes Care
Evaluation of two insulin assays in insulin resistance syndrome (syndrome X).
Steven M. Haffner, Leena Mykkänen, Rodolfo A. Valdez, Michael P. Stern · 1994 · Arteriosclerosis and Thrombosis A Journal of Vascular Biology
Autonomic dysfunction is related to impaired pancreatic β cell function in patients with coronary artery disease
Jeremy Sayer, B Marchant, S V Gelding, Jackie A. Cooper, Adam Timmis · 2000 · Heart
Proinsulin Is an Independent Predictor of the Angiographical Characteristics of Coronary Atherosclerosis
En‐Zhi Jia, Zhijian Yang, Tiebing Zhu, Liansheng Wang, Bo Chen, Kejiang Cao, JUN C. HUANG, Wen‐Zhu Ma · 2007 · Cardiology
Impaired proinsulin secretion before and during oral glucose stimulation in HIV-infected patients who display fat redistribution
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Biophysical alteration of the secretory track in β-cells due to molecular overcrowding: the relevance for diabetes
Constantin Ionescu-Tirgoviste, Florin Despa · 2010 · Integrative Biology
Prevalence of Undiagnosed Non‐Insulin‐Dependent Diabetes Mellitus and Impaired Glucose Tolerance in a Cohort of Older Persons with Hypertension
Karen Johnson, Marshall J. Graney, William B. Applegate, Abbas E. Kitabchi, John W. Runyan, Ronald I. Shorr · 1997 · Journal of the American Geriatrics Society
Proinsulin: recent observations and controversies
Robert Brian Mackin · 1998 · Cellular and Molecular Life Sciences
Processing and release of human proinsulin-cleavage products into culture media by different engineered non-endocrine cells: a specific assessment by capillary electrophoresis
Cinzia Arcelloni, Luca Falqui, Sabina Martinenghi, Angela Stabilini, A. E. Pontiroli, Rita Clara Paroni · 2000 · Journal of Endocrinology
Impact of the short-term, intense exercise on postprandial glycemia in type 2 diabetic patients treated with gliclazide
Szewieczek, Jan, Dulawa, Jan, Strzałkowska, Dorota, Hornik, Beata, Kawecki, Grzegorz · 2007 · Journal of Diabetes and its Complications
FK506-Binding Protein 2 Participates in Proinsulin Folding
Carolin Hoefner, Tenna Holgersen Bryde, Celina Pihl, Sylvia Naiga Tiedemann, Sophie Emilie Bresson, Hajira Ahmed Hotiana, Muhammad Saad Khilji, Theodore dos Santos, Michele Puglia, Paola Pisano et al. · 2023 · Biomolecules
Early clinical studies with liraglutide
Wolfgang Ekkehard Schmidt · 2010 · International Journal of Clinical Practice
Exploring proinsulin proteostasis: insights into beta cell health and diabetes
Parisima Ghaffarian Zavarzadeh, Kathigna Panchal, Dylan Bishop, Elizabeth Gilbert, Mahi Trivedi, Tovaria Kee, Srivastav Ranganathan, Anoop Arunagiri · 2025 · Frontiers in Molecular Biosciences
Associations between gastrointestinal humoral factors and pancreatic proteolytic enzymes in alcohol-related versus non-alcohol-related pancreatitis
Sakina H. Bharmal, Sayali A. Pendharkar, Ruma G. Singh, Maxim S. Petrov · 2018 · Alcohol
Removal of a high-fat diet, but not voluntary exercise, reverses obesity and diabetic-like symptoms in male C57BL/6J mice
Aikaterini Hatzidis, Jasmin A. Hicks, Rachel R. Gelineau, Nicole L. Arruda, Isabella Monteiro De Pina, Karyn E. O'Connell, Joseph A. Seggio · 2017 · HORMONES
Beta-cell function is disrupted in patients with systemic lupus erythematosus
Alicia García Dorta, Juan Carlos Quevedo-Abeledo, Íñigo Rúa‐Figueroa, Antonia María de Vera-González, Alejandra González Delgado, Lilian Medina-Vega, Agustín F. González-Rivero, F. Francisco-Hernández, Miguel Ángel González-Gay, Iván Ferraz‐Amaro · 2020 · Lara D. Veeken
Parallel changes of proinsulin and islet amyloid polypeptide in glucose intolerance
C.M MacNamara, Beryl A. Barrow, Susan E. Manley, J Lévy, Anne Clark, R. C. Turner · 2000 · Diabetes Research and Clinical Practice
8 Genetics of insulin action
BARBARA CALEEN HANSEN · 1993 · Baillière s Clinical Endocrinology and Metabolism
Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection
E. Ekholm, Nael Shaat, Jens Juul Holst · 2011 · Acta Diabetologica
Association of human carboxypeptidase E exon5 gene polymorphisms with angiographical characteristics of coronary atherosclerosis in a Chinese population
Jie Wang, Yun Zhang, Zhijian Yang, Tiebing Zhu, Lian‐Sheng Wang, Bo Chen, Kejiang Cao, Jun Huang, Wen‐Zhu Ma, En‐Zhi Jia · 2008 · Acta Pharmacologica Sinica
Cell Rejuvenation with Thiazolidinediones
David S.H. Bell · 2003
Limitations of the fasting proinsulin to insulin ratio as a measure of β‐cell health in people with and without impaired glucose tolerance
Aoife Maria Egan, MARCELLO C. LAURENTI, Maria Daniela Hurtado Andrade, Chiara Dalla Man, Claudio Cobelli, Kent R. Bailey, Adrian V Vella · 2020 · European Journal of Clinical Investigation
Abnormalities of Insulin Secretion and β‐Cell Defects in Type 2 Diabetes
Mazen Alsahli, John E. Gerich · 2010 · Wiley eBooks
Alcohol Use Behaviors, Fat Intake and the Function of Pancreatic β-Cells in Non-Obese, Healthy Korean Males: Findings from 2010 Korea National Health and Nutrition Examination Survey
Hye-Kyung Chung, Yoonsu Cho, Min‐Jeong Shin · 2013 · Annals of Nutrition and Metabolism
Molecular scanning of the human carboxypeptidase E gene for mutations in Chinese subjects with coronary atherosclerosis
En‐Zhi Jia, Jie Wang, Zhijian Yang, Tiebing Zhu, Lian‐Sheng Wang, Bo Chen, Kejiang Cao, Jun Huang, Wen‐Zhu Ma · 2007 · Molecular and Cellular Biochemistry
Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion
Quinn Dufurrena, Nils Bäck, Richard E. Mains, Louis Hodgson, Herbert Bernard Tanowitz, Prashant Mandela, Betty A. Eipper, Regina Kuliawat · 2018 · Journal of Molecular Endocrinology