The Hypercycle: A principle of natural self-organization Part C: The realistic hypercycle
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The hypercycle was proposed as a solution to the error threshold.
“The hypercycle was proposed by Eigen and Schuster [22,41,42,43] as a solution to the error threshold [1], a severe limit to the information content of primordial biological sequences.”
From Ecology and Evolution in the RNA World Dynamics and Stability of Prebiotic Replicator Systems (2017) · cites this paper as [42]
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- Authors
- Eigen, M., & Schuster, P.
- Affiliations
- Max Planck Institute for Biophysical Chemistry (DE)
- University of Vienna (AT)
- ORCID
- Schuster, Peter
- Venue
- The Science of Nature
- Published
- 1978-07
- Volume
- 65
- Issue
- 7
- Pages
- 341-369
- ISSN
- 0028-1042 (ISSN-L)
- 1432-1904
- OpenAlex
- W4240695170
- Cited by
- 487
- References
- 0
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 7 · 2023: 6 · 2022: 7 · 2021: 4 · 2020: 6 · 2019: 8 · 2018: 10 · 2017: 8 · 2016: 14 · 2015: 15 · 2014: 10 · 2013: 15 · 2012: 11
- FWCI
- 8.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Die Naturwissenschaften (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Keywords
- hypercycles, origin of life, translation (biology), quasispecies, genetic mutations, gene duplication, codon assignment, molecular evolution
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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