Wallerian degeneration in the peripheral nervous system: participation of both Schwann cells and macrophages in myelin degradation

Stoll, G.; Griffin, J. W.; Li, C. Y.; Trapp, B. D.

doi:10.1007/bf01187086

Wallerian degeneration in the peripheral nervous system: participation of both Schwann cells and macrophages in myelin degradation

This study examined the role of Schwann cells and hematogenous macrophages in myelin degradation and Ia antigen expression during Wallerian degeneration of rodent sciatic nerve. To identify and distinguish between macrophages and Schwann cells we used, in addition to electron microscopy, immunocy…