The DOI matches its Crossref record; 38 of the 39 references it cites were found in a registry or an index.
Plasma neurotransmitters and cortisol in duodenal ulcer patients: Role of stress
Abstract
Levels of noradrenaline, adrenaline, dopamine, free serotonin, platelet serotonin, and cortisol were measured in the plasma of duodenal ulcer patients and controls. All subjects received antacids, and these substances were also measured. During relapse, all patients showed raised noradrenaline, adrenaline, dopamine, free serotonin, and cortisol values. In contrast, platelet serotonin showed very low values, which correlated negatively with all the former, except free serotonin. No correlations were found in parameters of the controls. After healing, significant reductions of noradrenaline, adrenaline, dopamine, free serotonin, and cortisol and significant increases of platelet serotonin values were observed. However, only dopamine, free serotonin, and cortisol reached normal values. Noradrenaline and adrenaline remained higher and platelet serotonin lower, both significantly more so than normals. These still-altered parameters showed similar correlations to those found during relapses. The present results demonstrate that some baseline autonomic system imbalance exists in patients, amplified and accentuated during relapse. We discuss the possibility that stress plays some role in triggering duodenal ulcer relapse.
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“In correlation with non-depressed individuals, depressed individuals have been found to have raised plasma catecholamine levels, including norepinephrine, epinephrine, and dopamine, high free-serotonin levels and low platelet-serotonin levels; [23-26]”
From A pilot study on the effects of exercise on depression symptoms using levels of neurotransmitters and EEG as markers (2014) · cites this paper as [25]
In the citing paper
“In correlation with non-depressed individuals, depressed individuals have been found to have raised plasma catecholamine levels, including norepinephrine, epinephrine, and dopamine, high free-serotonin levels and low platelet-serotonin levels; [23-26]”
From A pilot study on the effects of exercise on depression symptoms using levels of neurotransmitters and EEG as markers (2014) · cites this paper as [25]
In the citing paper
“Although this study was not able to replicate the degree of findings from previous studies examining catecholamine and 5HT levels, [20,21,25-28] this study did show a reduction in serum levels of catecholamine and 5HT levels within the exercise group; however, these decreases were not significant.”
From A pilot study on the effects of exercise on depression symptoms using levels of neurotransmitters and EEG as markers (2014) · cites this paper as [25]
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Iosifescu, D. V., Bankier, B., & D, M. F. M. (2004) · Current Psychiatry Reports · doi:10.1007/s11920-004-0064-2 · Cited by 65
Metadata
- Authors
- Lechin, F., van der Dijs, B., Rada, I., Jara, H., Lechin, A. E., Cabrera, A., Lechin, M. E., Jimènez, V., Gòmez, F., Villa, S., Acosta, E., & Arocha, L.
- Affiliations
- Universidad Central de Venezuela (VE)
- Venue
- Digestive Diseases and Sciences
- Published
- 1990-11
- Volume
- 35
- Issue
- 11
- Pages
- 1313-1319
- ISSN
- 0163-2116 (ISSN-L)
- 1573-2568
- OpenAlex
- W2329891132
- Cited by
- 35
- References
- 39
- Citations by year
- 2019: 1 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Digestive Diseases and Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Helicobacter pylori-related gastroenterology studies
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- duodenal ulcer, cortisol, norepinephrine, epinephrine, dopamine, platelet serotonin, ulcer recurrence, autonomic imbalance, stress, ulcer healing
- MeSH terms
- Adult, Clonidine, Dopamine, Duodenal Ulcer, Epinephrine, Female, Humans, Hydrocortisone, Male, Middle Aged, Norepinephrine, Psychiatric Status Rating Scales, Recurrence, Serotonin, Stress, Physiological, Wound Healing, Neurotransmitter Agents
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