Wine aroma
Cited by (466)
Items 201–300 of 466
- Volatile composition of Bobal red wines subjected to alcoholic/malolactic fermentation with oak chipsE. Gómez García‐Carpintero, E. Sánchez‐Palomo, Miguel Ángel González Viñas · 2013 · LWT
- Effects of Different β-D-Glycosidases on Bound Aroma Compounds in Muscat Grape Determined by HS-SPME and GC-MSWenhuai Kang, Yan Xu, Ling Qin, Yuxia Wang · 2010 · Journal of the Institute of Brewing
- Influence of packaging and aging on the red wine volatile composition and sensory attributesN. Moreira, Paulo Lopes, H. Ferreira, Miguel Cabral, Paula Guedes de Pinho · 2016 · Food Packaging and Shelf Life
- Static Headspace Analysis Using Low-Pressure Gas Chromatography and Mass Spectrometry, Application to Determining Multiple Partition Coefficients: A Practical Tool for Understanding Red Wine Fruity Volatile Perception and the Sensory Impact of Higher AlcoholsMargaux Cameleyre, Georgia Lytra, Jean‐Christophe Barbe · 2018 · Analytical Chemistry
- Comprehensive 2D Gas Chromatography with TOF-MS Detection Confirms the Matchless Discriminatory Power of Monoterpenes and Provides In-Depth Volatile Profile Information for Highly Efficient White Wine Varietal DifferentiationIgor Lukić, Silvia Carlin, Urška Vrhovšek · 2020 · Foods
- Grape and Wine Composition in Vitis vinifera L. cv. Cannonau Explored by GC-MS and Sensory AnalysisGiacomo Luigi Petretto, Luca Mercenaro, Pietro Paolo Urgeghe, Costantino Fadda, Antonio Valentoni, ALESSANDRA DEL CARO · 2021 · Foods
- Concentration of volatile compounds in Chardonnay wine fermented in stainless steel tanks and oak barrelsAna González Marco, Nerea Jiménez‐Moreno, Carmen Ancín‐Azpilicueta · 2007 · Food Chemistry
- Assessment of free and immobilized kefir culture in simultaneous alcoholic and malolactic cider fermentationsAnastasios Nikolaou, Αlex Galanis, Maria Kanellaki, Chrysoula C. Tassou, Konstantoula Akrida‐Demertzi, Yiannis Kourkoutas · 2016 · LWT
- Making natural sparkling wines with non-Saccharomyces yeastsNedret Neslihan Ivit, Iris Loira, António Morata, Santiago Benito, Felipe Palomero, José Antonio Suárez-Lepe · 2017 · European Food Research and Technology
- Characterization of Cultivar Differences of Blueberry Wines Using GC-QTOF-MS and Metabolic Profiling MethodsFang Yuan, Ke Cheng, Jihui Gao, Siyi Pan · 2018 · Molecules
- Evaluation of Volatile Compounds during Ageing with Oak Chips and Oak Barrel of Muscat Ottonel WineAnamaria Călugăr, Teodora Emilia Coldea, Carmen Rodica Pop, Tiberia Ioana Pop, Anca Cristina BABEȘ, Claudiu Ioan Bunea, Mihail Manolache, Emese Gál · 2020 · Processes
- Aromatic characterization of traditional Chinese wine Msalais by partial least-square regression analysis based on sensory quantitative descriptive and odor active values, aroma extract dilution analysis, and aroma recombination and omission testsLixia Zhu, Mengmeng Zhang, Xiao‐Feng Xiang, Yi-Bing Lan, Ying Hua Shi, Chang‐Qing Duan, Ruili Zhang · 2021 · Food Chemistry
- Influence of some prefermentative treatments on aroma composition and sensory evaluation of white Godello winesManuel M. Losada, Jesús Andrés, Juan F Cacho, Eugenio Revilla, Jorge F. López · 2010 · Food Chemistry
- Cider fermentation with three Williopsis saturnus yeast strains and volatile changesMa Thandar Aung, Pin‐Rou Lee, Bin Yu, Shao‐Quan Liu · 2014 · Annals of Microbiology
- Optimization of Fermentation Conditions for Production of the Jabuticaba ( Myrciaria cauliflora ) Spirit Using the Response Surface MethodologyWhasley Ferreira Duarte, Juliana Cunha Amorim, Lilian de Assis Lago, Disney Ribeiro Dias, Rosane Freitas Schwan · 2011 · Journal of Food Science
- Effects of spontaneous and inoculated fermentation on the volatile profile of lychee ( Litchi chinensis Sonn) fermented beveragesJuliana Alvarenga Alves, Luiz Carlos de Oliveira Lima, Disney Ribeiro Dias, Cleiton Antônio Nunes, Rosane Freitas Schwan · 2010 · International Journal of Food Science & Technology
- Freeze-dried wheat supported biocatalyst for low temperature wine makingPanagiotis Kandylis, M.-E. Manousi, Argyro Bekatorou, A. A. Koutinas · 2010 · LWT
- Influence of prefermentation clarification on the higher alcohol contents of winesCarmen Ancı́n, Belén Ayestarán, Manuel Corroza, Julián J. Garrido, Alberto González · 1996 · Food Chemistry
- Impact of Using New Commercial Glutathione Enriched Inactive Dry Yeast Oenological Preparations on the Aroma and Sensory Properties of WinesInmaculada Andújar‐Ortiz, Carolina Chaya, Pedro J. Martín-Álvarez, María Victoria Moreno-Arribas, María Ángeles Pozo‐Bayón · 2013 · International Journal of Food Properties
- Influence of Nutrients Addition to Nonlimited‐in‐Nitrogen Must on Wine Volatile CompositionAna González Marco, Nerea Jiménez‐Moreno, Carmen Ancín‐Azpilicueta · 2010 · Journal of Food Science
- Study of volatile aroma components in young Tokaji Aszu wines by GC-MSÉ. Miklósy, Z. Kalmár, V. Pölös, Zoltán Kerényi · 2000 · Chromatographia
- Using mixed inocula of Saccharomyces cerevisiae killer strains to improve the quality of traditional sparkling-wineRocío Velázquez, Emiliano Zamora, M. Torres Alvarez, María L. Álvarez, Manuel Ramírez · 2016 · Food Microbiology
- Isolation, Selection, and Identification Techniques for Non-Saccharomyces Yeasts of Oenological InterestIris Loira, António Morata, María Antonia Bañuelos, Suárez-Lepe José Antonio · 2019 · Elsevier eBooks
- Understanding human salivary esterase activity and its variation under wine consumption conditionsMaría Pérez‐Jiménez, Carolina Muñoz‐González, María Ángeles Pozo‐Bayón · 2020 · RSC Advances
- The effect of heat and light on the composition of some volatile compounds in wineMaurizio D’Auria, Lucia Emanuele, Rocco Racioppi · 2009 · Food Chemistry
- Effect of seasonal climate fluctuations on the evolution of glycoconjugates during the ripening period of grapevine cv. Muscat à petits grains blancs berriesJulia Crespo, Peggy Rigou, Valeria Romero, Margarita Jiménez García, Teresa Arroyo, Juan Mariano Cabellos · 2017 · Journal of the Science of Food and Agriculture
- Volatile Compounds of Wines Produced by Cells Immobilized on Grape SkinsAthanasios Mallouchos, Panagiotis N. Skandamis, Paul Loukatos, Michael Komaitis, Αθανάσιος Α. Κουτίνας, Maria Kanellaki · 2003 · Journal of Agricultural and Food Chemistry
- Influence of Triazole Pesticides on Wine Flavor and Quality Based on Multidimensional Analysis TechnologyOuli Xiao, Minmin Li, Jieyin Chen, Ruixing Li, Rui Quan, Zezhou Zhang, Zhiqiang Kong, Xiaofeng Dai · 2020 · Molecules
- Thiamine and Biotin: Relevance in the Production of Volatile and Non-Volatile Compounds during Saccharomyces cerevisiae Alcoholic Fermentation in Synthetic Grape MustMarie Sarah Evers, Chloé Roullier‐Gall, Christophe Morge, Céline Sparrow, Antoine Gobert, Stefania Vichi, Hervé Alexandre · 2023 · Foods
- A comparative study of the volatile content of Mencía wines obtained using different pre-fermentative maceration techniquesMihaela Mihnea, M.L. González-SanJosé, Miriam Ortega-Herás, Silvia Pérez‐Magariño · 2015 · LWT
- Foreign and Undesirable Flavours in WineA. Rapp, Pieter J. Pretorius, D. Kugler · 1992 · Developments in food science
- Effects of Basal Defoliation on Wine Aromas: A Meta-AnalysisYu Wang, Lei He, Qiu‐Hong Pan, Chang‐Qing Duan, Jun Wang · 2018 · Molecules
- Stereoisomeric flavor compounds XLIV: Enantioselective analysis of some important flavor moleculesArmin Mosandl, Günther Bruche, Christiane Askari, Hans‐Georg Schmarr · 1990 · Journal of High Resolution Chromatography
- Characterization of polymeric pigments and pyranoanthocyanins formed in microfermentations of non-SaccharomycesyeastsCarlos Escott, António Morata, Iris Loira, Wendu Tesfaye, José Antonio Suárez-Lepe · 2016 · Journal of Applied Microbiology
- Influence of Freeze Concentration Technique on Aromatic and Phenolic Compounds, Color Attributes, and Sensory Properties of Cabernet Sauvignon WineYanyan Wu, Kai Xing, Xiaoxu Zhang, Hui Wang, Yong Wang, Fang Wang, Jingming Li · 2017 · Molecules
- Influence of supplementary irrigation on the amino acid and volatile composition of Godello wines from the Ribeiro Designation of OriginYolanda Bouzas-Cid, Emiliano Trigo-Córdoba, Elena Falqué, Ignacio Orriols, José Manuel Mirás‐Avalos · 2018 · Food Research International
- Changes in the polyphenolic and volatile content of “Fino” Sherry wine exposed to high temperature and ultraviolet and visible radiationPatricia Benı́tez, Remedios Castro, Ramón Natera, Carmelo Garcı́a Barroso · 2005 · European Food Research and Technology
- Enhancement of activity and stability of lipase by microemulsion-based organogels (MBGs) immobilization and application for synthesis of arylethyl acetateWeiwei Zhang, Na Wang, Yujie Zhou, Ting He, Xiao‐Qi Yu · 2012 · Journal of Molecular Catalysis B Enzymatic
- Characterisation of the volatile fraction of Andalusian sweet winesRaquel Márquez, Remedios Castro, Ramón Natera, Carmelo Garcı́a Barroso · 2007 · European Food Research and Technology
- Influence of the harvest date on berry compositions and wine profiles of Vitis vinifera L. cv. ‘Cabernet Sauvignon’ under a semiarid continental climate over two consecutive yearsXiaotong Gao, Huiqing Li, Yu Wang, Wen-Ting Peng, Wu Chen, Xiaodong Cai, Shu-De Li, Fei He, Chang‐Qing Duan, Jun Wang · 2019 · Food Chemistry
- Impact of UV-C treatment and thermal pasteurization of grape must on sensory characteristics and volatiles of must and resulting winesPatricia Golombek, Michael Wacker, Nina Buck, Dominik Durner · 2020 · Food Chemistry
- Performance of a novel β-glucosidase BGL0224 for aroma enhancement of Cabernet Sauvignon winesJie Zhang, Tieru Wang, Ning Zhao, Junnan Xu, Yiman Qi, Xinyuan Wei, Mingtao Fan · 2021 · LWT
- Evolution of esters in aged Chardonnay wines obtained with different vinification methodsCarmen Ancín‐Azpilicueta, Ana González Marco, Nerea Jiménez‐Moreno · 2009 · Journal of the Science of Food and Agriculture
- Vinification Effects on Changes in Volatile Compounds of WineE. GÓMEZ, J. Laencina, A. MARTINEZ · 1994 · Journal of Food Science
- Modelling of low temperature wine-making, using immobilized cellsPanagiotis Kandylis, Aikaterini Mantzari, Αθανάσιος Α. Κουτίνας, Ioannis K. Kookos · 2012 · Food Chemistry
- Aromatic Compounds in Wines Produced During Fermentation: Effect of Three Red CultivarsMar Vilanova, Sandra Cortés, J.L. Santiago, María-Carmen Martínez, Esperanza Fernández · 2007 · International Journal of Food Properties
- Characterization of volatile fraction of typical Irpinian wines fermented with a new starter yeastAntonella Calabretti, F. La Cara, Alida Sorrentino, Michele Di Stasio, Fabio Santomauro, Luca Rastrelli, Luciana Favretto Gabrielli, F. Limone, Maria Grazia Volpe · 2011 · World Journal of Microbiology and Biotechnology
- Effect of five enological practices and of the general phenolic composition on fermentation-related aroma compounds in Mencia young red winesAna Añón, Jorge F. López, Diego Hernando, Ignacio Orriols, Eugenio Revilla, Manuel M. Losada · 2013 · Food Chemistry
- VOLATILE CONSTITUENTS OF ORANGE WINE OBTAINED FROM MORO ORANGES (CITRUS SINENSIS[L.] OSBECK)Serkan Selli · 2007 · Journal of Food Quality
- Enzymes Extracted from Apple Peels Have Activity in Reducing Higher Alcohols in Chinese LiquorsQi’an Han, Junling Shi, Jing Zhu, Hongliang Lv, Shuang‐kui Du · 2014 · Journal of Agricultural and Food Chemistry
- New oenological practice to promote non-Saccharomyces species of interest: saturating grape juice with carbon dioxideLaura Chasseriaud, Joana Coulon, Philippe Marullo, Warren Albertin, Marina Bely · 2018 · Applied Microbiology and Biotechnology
- Acacia, cherry and oak wood chips used for a short aging period of rosé wines: effects on general phenolic parameters, volatile composition and sensory profileFilipa Santos, Ana Cristina Correia, Miriam Ortega-Herás, Javier García‐Lomillo, María José, António M. Jordão, Jorge Manuel Ricardo-Da-Silva · 2019 · Journal of the Science of Food and Agriculture
- Cell-Wall Degrading Enzymes in the Release of Grape Aroma PrecursorsMaría Angélica Ganga, Francisco Piñaga, Amparo Querol, Salvador Vallés, Daniel Ramón · 2001 · Food Science and Technology International
- Impact of two Williopsis yeast strains on the volatile composition of mango wineXiao Li, Bin Yu, Philip Curran, Shao‐Quan Liu · 2012 · International Journal of Food Science & Technology
- The Antarctic yeast Candida sake: Understanding cold metabolism impact on wineLidia Ballester‐Tomás, Jose Antonio Prieto, José Vicente Gil, Marcelo Baeza, Francisca Rández‐Gil · 2017 · International Journal of Food Microbiology
- Free Monoterpene Isomer Profiles of Vitis Vinifera L. cv. White WinesSong Mei, Claudio Fuentes, Athena Loos, Elizabeth Tomasino · 2018 · Foods
- Terpenoids in Grapes and Wines: Origin and Micrometabolism during the Vinification ProcessFrancisco M. Carrau, Eduardo Boido, Eduardo S. Dellacassa · 2008 · Natural Product Communications
- The Effects of Grape Polysaccharides Extracted from Grape By-Products on the Chemical Composition and Sensory Characteristics of White WinesSilvia Pérez‐Magariño, Estela Cano-Mozo, Marta Bueno‐Herrera, Diego Canalejo, Thierry Doco, Belén Ayestarán, Zenaida Guadalupe · 2022 · Molecules
- Harvest date effects on aroma compounds in aged Riesling icewinesRamsey Khairallah, Andrew G. Reynolds, Amy J. Bowen · 2016 · Journal of the Science of Food and Agriculture
- Determination of acetaldehyde, methanol and fusel oils in distilled liquors and sakès by headspace gas chromatographyYan Qin, Jung‐Ah Shin, Ki‐Teak Lee · 2019 · Food Science and Biotechnology
- Wine AromaUlrich Fischer · 2007 · Springer eBooks
- Volatiles of orange juice and orange wines using spontaneous and inoculated fermentationsGang Fan, Xiaoyun Xu, Yu Qiao, Yongxia Xu, Yun Zhang, Li Li, Siyi Pan · 2009 · European Food Research and Technology
- Investigation of a Quantitative Method for the Analysis of Chiral Monoterpenes in White Wine by HS-SPME-MDGC-MS of Different Wine MatricesSong Mei, Ying Xia, Elizabeth Tomasino · 2015 · Molecules
- Volatile flavour components of mandarin wine obtained from clementines (Citrus reticula Blanco) extracted by solid‐phase microextractionSerkan Selli, Mine Kürkçüoğlu, Ebru Kafkas, Turgut Cabaroğlu, Betül Demırcı, K. Hüsnü Can Başer, Ahmet Canbaş · 2004 · Flavour and Fragrance Journal
- Sensory and chemical changes in Chilean Cabernet Sauvignon wines during storage in bottles at different temperaturesHanne Sivertsen, Erik Figenschou, Frithjof Nicolaysen, Einar Risvik · 2001 · Journal of the Science of Food and Agriculture
- Mead: The Oldest Alcoholic BeverageRajko Vidrih, Janez Hribar · 2016 · Springer eBooks
- Non-Saccharomyces Yeasts in the Winemaking ProcessPaloma Manzanares, Salvador Vallés, Fernando Viana · 2011 · Elsevier eBooks
- Aromastoffe des WeinesA. Rapp · 1992 · Chemie in unserer Zeit
- Flavonoid and aromatic characterisation of cv. Albarín blanco (Vitis vinifera L.)Antón Masa, Mar Vilanova · 2007 · Food Chemistry
- Postfermentation Treatments and Related TopicsRonald S. Jackson · 2008 · Elsevier eBooks
- Foam aptitude of Bobal variety in white sparkling wine elaboration and study of volatile compoundsMarı́a José Garcı́a, José Luis Aleixandre, Inmaculada Álvarez, Victoria Lizama · 2009 · European Food Research and Technology
- Changes in anthocyanins and volatile components of purple sweet potato fermented alcoholic beverage during agingSuhong Li, Yingfeng An, Weina Fu, Xiao Sun, Wenjie Li, Tuoping Li · 2017 · Food Research International
- Effect of inoculation strategy of non‐ Saccharomyces yeasts on fermentation characteristics and volatile higher alcohols and esters in Campbell Early winesSu-Hyun Lee, C. Banda, Heui-Dong Park · 2019 · Australian Journal of Grape and Wine Research
- Comparative study of the volatile composition in wines obtained from traditional vinification and from the Ganimede methodTeresa Garde‐Cerdán, Idoia Jarauta, M. Rosario Salinas, Carmen Ancín‐Azpilicueta · 2008 · Journal of the Science of Food and Agriculture
- Aromatic complexity in Verdicchio wines: a case studySilvia Carlin, Urška Vrhovšek, Andrea Lonardi, Lorenzo Landi, Fulvio Mattivi · 2019 · OENO One
- Wine Stabilisation: An Overview of Defects and TreatmentsFernanda Cosme, Luı́s Filipe-Ribeiro, Fernando M. Nunes · 2021 · IntechOpen eBooks
- Volatile flavour constituent patterns of Terras Madeirenses red wines extracted by dynamic headspace solid‐phase microextractionRosa Perestrelo, Michael Caldeira, Freddy Rodrigues, José S. Câmara · 2008 · Journal of Separation Science
- Wine Preference and Wine Aroma PerceptionMaría Ángeles Pozo‐Bayón, Carolina Muñoz‐González, Adelaida Esteban‐Fernández · 2016 · Springer eBooks
- Characterisation of free and glycosidically bound odourant compounds of Aragonez clonal musts by GC-OGoreti Botelho, Arlete Mendes‐Faia, Maria Cristina Clímaco · 2009 · Analytica Chimica Acta
- Evolution of Volatile Byproducts during Wine Fermentations Using Immobilized Cells on Grape SkinsAthanasios Mallouchos, Michael Komaitis, Αθανάσιος Α. Κουτίνας, Maria Kanellaki · 2003 · Journal of Agricultural and Food Chemistry
- Differentiation of Commercial PDO Wines Produced in Istria (Croatia) According to Variety and Harvest Year Based on HS-SPME-GC/MS Volatile Aroma Compounds ProfilingIgor Lukić, Ivana Horvat · 2016 · Food Technology and Biotechnology
- Rootstock Effect on Volatile Composition of Albariño WinesMar Vilanova, Zlatina Asenova Genisheva, Miguel Tubío, Katia Álvarez, José Ramón Lissarrague García-Gutiérrez, J. M. Oliveira · 2021 · Applied Sciences
- Freeze-Dried Saccharomyces cerevisiae Cells Immobilized on Potato Pieces for Low-Temperature WinemakingPanagiotis Kandylis, Dimitra Dimitrellou, Paraskevi Lymnaiou, Αθανάσιος Α. Κουτίνας · 2014 · Applied Biochemistry and Biotechnology
- Untersuchungen des Trauben- und WeinaromasA. Rapp, Iris Suckrau, Giuseppe Versini · 1993 · European Food Research and Technology
- Synthesis of alkyl sulfonic acid aldehydes and alcohols, putative precursors to important wine aroma thiolsNina Duhamel, Federico Piano, Samuel James Davidson, Roberto Larcher, Bruno Fedrizzi, David L. A. Barker · 2015 · Tetrahedron Letters
- Evolution of the aromatic profile of traditional Msalais wine during industrial productionLi-Xia Zhu, Meng-Meng Zhang, Yin Shi, Chang‐Qing Duan · 2019 · International Journal of Food Properties
- Influence of Oak Chips and Oak Barrel Ageing on Volatile Profile in Chardonnay Wine of RomaniaDiana Ionela Stegăruș, Anamaria Călugăr, Corneliu Tanase, Adriana Muscă, Oana Romina Botoran, Mihail Manolache, Anca Cristina BABEȘ, Claudiu Ioan Bunea, Emese Gál, Andrea Bunea et al. · 2021 · Applied Sciences
- Monitoring of the Wines’ Quality by Gas Chromatography: HSS-GC/FID Method Development, Validation, Verification, for Analysis of Volatile CompoundsSaša Šorgić, Ivana Sredović Ignjatović, Mališa Antić, Sabina Šaćirović, Lato L. Pezo, Vladimir Čejić, Saša D. Đurović · 2022 · Fermentation
- Winemaking by barley supported yeast cellsPanagiotis Kandylis, Dimitra Dimitrellou, Αθανάσιος Α. Κουτίνας · 2011 · Food Chemistry
- Volatile composition of Pedro Ximénez and Muscat sweet Sherry wines from sun and chamber dried grapes: a feasible alternative to the traditional sun-dryingMaría Jesús Ruiz-Bejarano, Remedios Castro, M. Carmen Rodríguez Dodero, Carmelo Garcı́a Barroso · 2016 · Journal of Food Science and Technology
- Wine and HeterocyclesHeinrich Wamhoff, Gordon W. Gribble · 2012 · Advances in heterocyclic chemistry
- Headspace Analysis ofVitis vinifera(Vitaceae) FlowersGerhard Buchbauer, Leopold Jirovetz, Michael Wasicky, Alexej Nikiforov · 1994 · Journal of Essential Oil Research
- Free and glycosylated simple phenol profiling in Apulian Italian winesC. Barnaba, Eduardo S. Dellacassa, Giorgio Nicolini, Tiziana Nardin, M. Malacarne, Roberto Larcher · 2016 · Food Chemistry
- Fate of carotenoids in yeasts: synthesis and cleavageQian-Wei Zhang, Cai-Lin Kong, Yongsheng Tao · 2022 · Critical Reviews in Food Science and Nutrition
- Distinctive Characteristics of Madeira Wine Regarding Its Traditional Winemaking and Modern Analytical MethodologiesRosa Perestrelo, Francisco Albuquerque, Sı́lvia M. Rocha, José S. Câmara · 2011 · Advances in food and nutrition research
- Effect of fusel oil addition on volatile compounds in papaya wine fermented with Williopsis saturnus var. mrakii NCYC 2251Pin‐Rou Lee, Bin Yu, Philip Curran, Shao‐Quan Liu · 2010 · Food Research International
- Influence of different yeast/lactic acid bacteria combinations on the aromatic profile of red Bordeaux wineMarine Gammacurta, Stéphanie Marchand, Virginie Moine, Gilles de Revel · 2017 · Journal of the Science of Food and Agriculture
- Volatilome of white wines as an indicator of authenticity and adulteration control using statistical analysisIoannis K. Karabagias, Vassilios K. Karabagias, Anastasia V. Badeka · 2021 · Australian Journal of Grape and Wine Research
- Influence of some oenological practices on the aromatic and sensorial characteristics of white Verdejo winesManuel M. Losada, Jorge F. López, Ana Añón, Jesús Andrés, Eugenio Revilla · 2012 · International Journal of Food Science & Technology
- Development of C6 and Other Volatile Compounds in Pinot Noir Grapes Determined by Stir Bar Sorptive Extraction-GC-MSYu Fang, Michael C. Qian · 2012 · ACS symposium series