Effects of thiamine supplementation on exercise-induced fatigue
Abstract
High-dose thiamine (vitamin B1) supplementation (100 mg/day) may be helpful in preventing or accelerating recovery from exercise-induced fatigue. Sixteen volunteer male athletes volunteer, 8 with a blood thiamine level of 40 ng/ml or more (normal thiamine group) and 8 with levels below that level (low thiamine group) were selected as subjects. They exercised on a bicycle ergometer and the effects of thiamine supplementation were compared with placebo. Blood thiamine level markedly increased following supplementation of thiamine for 3 days before exercise. Exercise-induced changes in hemodynamic parameters and cardiopulmonary function indicated the onset of fatigue. Thiamine supplementation significantly suppressed the increase in blood glucose in the normal thiamine group and significantly decreased the number of complaints shortly after exercise in the subjective fatigue assessment of 30 items.
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High-dose thiamine supplementation (100 mg/day for 3 days) decreases subjective fatigue complaints after cycling exercise in young athletes.
“In 16 young athletes, high-dose thiamine (vitamin B1) supplementation (100 mg/day) for 3 days markedly increased blood thiamine level and significantly decreased the number of complaints after a cycling exercise, in a subjective fatigue assessment [118].”
From Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence (2020) · cites this paper as [118]
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References 9 · Cited by 36
- Authors
- Suzuki, M., & Itokawa, Y.
- Affiliations
- University of Tsukuba (JP)
- Kyoto University (JP)
- Venue
- Metabolic Brain Disease
- Published
- 1996-03
- Volume
- 11
- Issue
- 1
- Pages
- 95-106
- ISSN
- 0885-7490 (ISSN-L)
- 1573-7365
- OpenAlex
- W2068600652
- Cited by
- 36
- References
- 9
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 2 · 2015: 3 · 2013: 1 · 2012: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Metabolic Brain Disease (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of Tsukuba
- Topics
- Health Sciences › Medicine › Neurology › Alcoholism and Thiamine Deficiency
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Keywords
- thiamine supplementation, thiamine, exercise fatigue, athletes, blood thiamine levels, blood glucose, hemodynamic parameters, cardiopulmonary function, subjective fatigue, post-exercise recovery
- MeSH terms
- Adult, Blood Glucose, Double-Blind Method, Exercise Test, Fursultiamin, Hemodynamics, Humans, Lactates, Male, Oxygen Consumption, Thiamine, Exercise, Cross-Over Studies, Muscle Fatigue, Lactic Acid
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