Methods for the study of histocompatibility genes
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True congenic mice are generated through at least 10 backcrosses, at which point mice are expected to contain 99.9% of their genetic information from the backcrossed background.
“True congenic mice are generated through a series at least 10 backcrosses, at which point mice are expected to contain 99.9% of their genetic information from the backcrossed background (Snell, 1948).”
From Rodent Genetic Models of Ah Receptor Signaling (2021) · cites this paper as Snell, 1948
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Rodent Genetic Models of Ah Receptor Signaling
Wilson, R. H., & Bradfield, C. A. (2021) · Drug Metabolism Reviews · doi:10.1080/03602532.2021.1955916 · Cited by 16 · see citing works
“True congenic mice are generated through a series at least 10 backcrosses, at which point mice are expected to contain 99.9% of their genetic information from the backcrossed background (Snell 1948).”
BackgroundInfluential
- Authors
- Snell, G. D.
- Affiliations
- Jackson Laboratory (US)
- Corresponding author
- Snell, G. D.
- Venue
- Journal of Genetics
- Published
- 1948-10
- Volume
- 49
- Issue
- 2
- Pages
- 87-108
- ISSN
- 0022-1333 (ISSN-L)
- OpenAlex
- W2094970674
- Cited by
- 476
- References
- 0
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 7 · 2023: 3 · 2022: 9 · 2021: 9 · 2020: 9 · 2019: 5 · 2018: 6 · 2017: 6 · 2016: 3 · 2015: 13 · 2014: 8 · 2013: 10 · 2012: 13
- FWCI
- 2.51
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Genetics (publishedVersion)
- PubMed (publishedVersion)
- The Mouseion at the JAXlibrary (Jackson Laboratory) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Health Sciences › Medicine › Transplantation › Renal Transplantation Outcomes and Treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Keywords
- histocompatibility genes, histocompatibility, histocompatibility testing, histocompatibility antigens
- MeSH terms
- Genetics, Humans
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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