Primary abdominal wall clear cell carcinoma arising in a Caesarean section scar endometriosis
Abstract
Background Endometriosis occurring in a surgical scar is well recognized and occurs mainly in patients with a history of hysterectomy or Caesarean section. Scar endometriosis, as well as endometriosis at other sites, can undergo malignant change. Endometrioid carcinoma is the most common malignant tumour arising in endometriosis. However, clear cell carcinoma can also occur but is unusual.Aim To discuss the diagnosis and management of such a case.Methods We report a case of primary clear cell carcinoma in endometriosis of a Caesarean section scar and review the literature.Results The patient presented with a large right lower quadrant abdominal wall mass within a Caesarean section scar. Histological examination revealed a clear cell carcinoma. The patient had a prior history of pelvic endometriosis. According to the Irish National Cancer Registry, this is the first reported case of a primary abdominal wall clear cell carcinoma developing within a Caesarean section scar in Ireland.Conclusion Any lesion occurring in a Caesarean section scar with a history of previous endometriosis cannot be underestimated and warrants careful clinical follow-up and histological evaluation as appropriate.
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CSE can undergo malignant change, which is rapidly fatal and has a survival rate of only 57%.
“Additionally, CSE can undergo malignant change, which is rapidly fatal and has a survival rate of only 57% [14].”
From Cesarean scar endometriosis: presentation of 198 cases and literature review (2019) · cites this paper as [14]
The tumor often involves the rectus abdominis muscle and may protrude into the abdominal cavity as noted in the second case described.
“The tumor often involves the rectus abdominis muscle and may protrude into the abdominal cavity as noted in the second case described [18].”
From Clear cell carcinoma arising from abdominal wall endometriosis—A report on two cases and literature review (2022) · cites this paper as [18]
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References 7 · Cited by 51
- Authors
- Alberto, V. O., Lynch, M., Labbei, F. N., & Jeffers, M.
- Affiliations
- Tallaght University Hospital (IE)
- Venue
- Irish Journal of Medical Science
- Published
- 2006-03
- Volume
- 175
- Issue
- 1
- Pages
- 69-71
- ISSN
- 0021-1265 (ISSN-L)
- 1863-4362
- OpenAlex
- W2088479821
- Cited by
- 51
- References
- 7
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 6 · 2020: 4 · 2019: 3 · 2017: 5 · 2016: 1 · 2015: 3 · 2014: 2 · 2013: 2 · 2012: 4
- FWCI
- 2.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Irish Journal of Medical Science (1971 -) (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Metastasis and carcinoma case studies
- Health Sciences › Medicine › Surgery › Urinary and Genital Oncology Studies
- Keywords
- clear cell carcinoma, endometriosis, cesarean section scar, abdominal wall mass, endometrioid carcinoma, malignant transformation of endometriosis, pelvic endometriosis, postoperative scarring
- MeSH terms
- Adult, Cesarean Section, Cicatrix, Endometriosis, Female, Humans, Adenocarcinoma, Clear Cell, Carcinoma, Endometrioid
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