Radiation protection recommendations for I-131 thyrotoxicosis, thyroid cancer and phaeochromocytoma patients
Abstract
Iodine-131 patients pose a radiation risk to their family members, carers and colleagues. Doses from thyrotoxicosis and thyroid cancer patients undergoing standard treatments have been well characterised in the literature. However the resulting precautions cannot be easily adapted to circumstances where the patient has an unusual affliction, or an atypical family or occupational environment. In this study, a model for calculating dose from an I-131 patient is derived from first principles. The model is combined with existing results from the literature to determine a distance weighting factor between patients and family members. This technique reduces the uncertainty in the dose calculations by removing the need to guess the unknown patterns of close contact, a problem common to all previous dose calculation techniques. Data is presented for four unusual I-131 treatments; a child thyroid cancer patient, two thyroid cancer dialysis patients and a phaeochromocytoma patient. The model is used to calculate appropriate periods of restricted contact for these patients. The recommendations provide a useful guide for future unusual I-131 treatments.
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In the United States, the treating physician must ensure and document that no adult member of the public is exposed to 0.5 mSv when the patient is discharged with a retained activity of 33 mCi or greater, or emits at least 7 mrem/h at 1 m.
“In the United States, the treating physician must ensure and document that no adult member of the public is exposed to 0.5 mSv (500 milli-roentgen equivalent in man [mrem]) when the patient is discharged with a retained activity of 33 mCi (1.22 GBq) or greater, or emits ‡7 mrem/h (70 lSv/h) at 1 m.”
From 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis (2016) · cites this paper as [104]
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References 19 · Cited by 9
- Authors
- Woodings, S.
- Affiliations
- Royal Perth Hospital (AU)
- Corresponding author
- Woodings, S.
- Venue
- Australasian Physics & Engineering Sciences in Medicine
- Published
- 2004-09
- Volume
- 27
- Issue
- 3
- Pages
- 118-128
- ISSN
- 0158-9938 (ISSN-L)
- 1879-5447
- OpenAlex
- W2071045942
- Cited by
- 9
- References
- 19
- Citations by year
- 2025: 1 · 2024: 1 · 2018: 1 · 2016: 1
- FWCI
- 0.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Australasian Physical & Engineering Sciences in Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiation Dose and Imaging
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiopharmaceutical Chemistry and Applications
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Effects of Radiation Exposure
- Keywords
- iodine-131, radiation protection, thyrotoxicosis, thyroid cancer, pheochromocytoma, dose calculation model, dialysis patients, occupational radiation exposure
- MeSH terms
- Adult, Algorithms, Australia, Body Burden, Child, Preschool, Humans, Iodine Radioisotopes, Models, Biological, Pheochromocytoma, Radiation Injuries, Radiation Protection, Radiometry, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted, Relative Biological Effectiveness, Thyroid Neoplasms, Thyrotoxicosis, Occupational Exposure, Guidelines as Topic, Risk Assessment, Radiopharmaceuticals
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