Expanding human beta cells
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Expansion of bona fide human β-cells has not been convincingly demonstrated.
“Sadly, expansion of bona fide human β-cells has not been convincingly demonstrated (13–15).”
From Adaptive β-Cell Proliferation Is Severely Restricted With Advanced Age (2009) · cites this paper as [13]
Regeneration of β-cell function in experimental animal models has been widely observed in rodents but remains elusive and controversial in humans.
“Regeneration of β-cell function in experimental animal models has been widely observed in rodents but remains elusive and controversial in humans (13,14).”
From Adaptive β-Cell Proliferation Is Severely Restricted With Advanced Age (2009) · cites this paper as [13]
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References 10 · Cited by 9
- Authors
- Scharfmann, R.
- Affiliations
- Inserm (FR)
- Corresponding author
- Scharfmann, R.
- ORCID
- Scharfmann, R.
- Venue
- Diabetologia
- Published
- 2008-02-15
- Volume
- 51
- Issue
- 4
- Pages
- 692-693
- ISSN
- 0012-186X (ISSN-L)
- 1432-0428
- OpenAlex
- W2021044949
- Cited by
- 9
- References
- 10
- Citations by year
- 2025: 1 · 2016: 1 · 2014: 1 · 2013: 1
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Diabetologia (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Pancreatic function and diabetes
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Pluripotent Stem Cells Research
- Keywords
- beta-cell proliferation, human beta cells, beta-cell neogenesis, diabetes treatment, PDX1, Ki-67, bromodeoxyuridine, growth factors, islet transplantation
- MeSH terms
- Animals, Cell Differentiation, Diabetes Mellitus, Humans, Regeneration, Stem Cells, Models, Animal, Insulin-Secreting Cells, Rats
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