Cited by 154Diabetes Management and ResearchInsurance, Mortality, Demography, Risk ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Life expectancy of type 1 diabetic patients during 1997–2010: a national Australian registry-based cohort study

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Huo, Lili, Harding, Jessica L., Peeters, Anna, Shaw, Jonathan E., Magliano, Dianna J.·2016·Diabetologia

Abstract

Aims/hypothesis There is limited information about the impact of type 1 diabetes on life expectancy in a contemporary population. We examined the life expectancy of type 1 diabetic patients and explored the contribution of mortality at different ages and of different causes of death to years of life lost (YLL) compared with the general population. Methods We derived mortality rates of Australians with type 1 diabetes listed on the National Diabetes Services Scheme (NDSS) between 1997 and 2010 (n = 85,547) by linking the NDSS to the National Death Index. The Chiang method was used to estimate life expectancy and Arriaga's method was used to estimate the contributions of age-specific and cause-specific mortality to the YLL. Results A total of 5,981 deaths were identified during the 902,136 person-years of follow up. Type 1 diabetic patients had an estimated life expectancy at birth of 68.6 years (95% CI 68.1, 69.1), which was 12.2 years (95% CI 11.8, 12.7) less than that in the general population. The improvement in life expectancy at birth in 2004-2010 compared with 1997-2003 was similar for both type 1 diabetic patients (men, 1.9 years [95% CI 0.4, 3.3]; women, 1.5 years [95% CI 0.0, 3.2]) and the general population (men, 2.2 years; women, 1.4 years). Deaths at age <60 years accounted for 60% of the YLL from type 1 diabetes for men and 45% for women. The major contribution to YLL was mortality from endocrine and metabolic disease at age 10-39 years (men, 39-59%; women, 35-50%) and from circulatory disease at age ≥40 years (men, 43-75%; women, 34-75%). Conclusions/interpretation Data from 1997 to 2010 showed that Australian type 1 diabetic patients had an estimated loss in life expectancy at birth of 12.2 years compared with the general population.

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  • In Australia over 1997-2010, life expectancy of those with type 1 diabetes mellitus aged 60-64 years was 6.5 years shorter for men and 8.5 years shorter for women than in the general population of the same age.

    “An Australian analysis over 1997–2010 found that the life expectancy of those with T1DM aged 60–64 years was 6.5 years shorter for men and 8.5 years shorter for women than in the general population of the same age44.”

    From The epidemiology of type 1 diabetes mellitus in older adults (2025) · cites this paper as [44]

    The Estimated life expectancy section reports shorter life expectancy for Australian men and women with type 1 diabetes than for the general population, with the reduction declining as age increases. The passages available from Table 2 do not show the age 60–64 row, so they do not verify the specific losses of 6.5 and 8.5 years. (LLM, conf=0.78)

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Research works printed but not linked: 3

  1. Chiang CL (1984) Chapter
  2. Gordon-Dseagu VL, Shelton N, Mindell JS (2013) Epidemiological evidence of a relationship between type-1 diabe- tes mellitus and cancer: a review of the existing literature. Int J Cancer 132:501-508
  3. Maclaine GD, Macarthur EB, Heathcote CR (1992) A comparison of death certificates and autopsies in the Australian Capital Territory. Med J Aust 156(462-463):466-468

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Authors
Huo, L., Harding, J. L., Peeters, A., Shaw, J. E., & Magliano, D. J.
Affiliations
Baker Heart and Diabetes Institute (AU)
Corresponding author
Huo, Lili
Venue
Diabetologia
Published
2016-01-21
Volume
59
Issue
6
Pages
1177-1185
ISSN
  • 0012-186X (ISSN-L)
  • 1432-0428
OpenAlex
W2295853094
Cited by
154
References
3
Citations by year
2026: 8 · 2025: 10 · 2024: 19 · 2023: 20 · 2022: 24 · 2021: 16 · 2020: 15 · 2019: 17 · 2018: 11 · 2017: 9 · 2016: 4
FWCI
13.70
Type
journal article
Language
en
Open access
Locations
  • Diabetologia (publishedVersion)
  • PubMed (publishedVersion)
  • Deakin Research Online (Deakin University) (submittedVersion)
  • Figshare (submittedVersion, cc-by)
Funders
National Health and Medical Research Council (APP1002663)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Social Sciences › Demography › Insurance, Mortality, Demography, Risk Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
type 1 diabetes, life expectancy, years of life lost, mortality, cause-specific mortality, age-specific mortality, endocrine and metabolic diseases, circulatory diseases, sex differences, Australian population
MeSH terms
Adolescent, Adult, Age Factors, Australia, Cardiovascular Diseases, Cause of Death, Child, Child, Preschool, Diabetes Mellitus, Type 1, Female, Humans, Infant, Infant, Newborn, Life Expectancy, Male, Registries, Risk Factors, Sex Factors, Cohort Studies, Young Adult

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