Assessment of nicotinic acetylcholine receptor subunit contributions to nicotine self-administration in mutant mice
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Both β2* and α7 nAChR subtypes contribute to nicotine-associated increases in DA release and associated nicotine-dependent behaviors.
“An accumulation of data suggests that both the β2* and α7 nAChR subtypes contribute to nicotine-associated increases in DA release and associated nicotine-dependent behaviors (Corrigall et al., 1994; Epping-Jordan et al., 1999; Laviolette and van der Kooy, 2003; Mansvelder et al., 2002; Picciotto et al., 1998; Pidoplichko et al., 2004; Shoaib and Stolerman, 1994).”
From It is not “either/or”: Activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood (2008) · cites this paper as Epping-Jordan et al., 1999
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References 4 · Cited by 86
- Authors
- Epping-Jordan, M. P., Picciotto, M. R., Changeux, J.-P., & Pich, E. M.
- Affiliations
- University of Lausanne (CH)
- Yale University (US)
- Institut Pasteur (FR)
- GlaxoSmithKline (Italy) (IT)
- Venue
- Psychopharmacology
- Published
- 1999-11-05
- Volume
- 147
- Issue
- 1
- Pages
- 25-26
- ISSN
- 0033-3158 (ISSN-L)
- 1432-2072
- OpenAlex
- W1972806087
- Cited by
- 86
- References
- 4
- Citations by year
- 2025: 1 · 2024: 1 · 2020: 3 · 2019: 4 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 4 · 2014: 4 · 2013: 6 · 2012: 8
- FWCI
- 1.15
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- nicotinic acetylcholine receptors, nicotinic receptor subunits, nicotine self-administration, mouse mutants, nicotine reinforcement
- MeSH terms
- Animals, Cocaine, Conditioning, Operant, Injections, Intravenous, Male, Mice, Inbred C57BL, Mice, Mutant Strains, Nicotine, Receptors, Nicotinic, Reinforcement, Psychology, Reinforcement Schedule, Self Administration, Nicotinic Agonists, Dopamine Uptake Inhibitors, Mice
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