Cited by 242Advanced Scientific Research MethodsFungal Biology and ApplicationsEnzyme Production and Characterization

Myco-protein from Fusarium venenatum: A well-established product for human consumption

Wiebe, M.·2002·Applied Microbiology and Biotechnology

Abstract

Fusarium venenatum A3/5 was first chosen for development as a myco-protein in the late 1960s. It was intended as a protein source for humans and after 12 years of intensive testing, F. venenatum A3/5 was approved for sale as food by the Ministry of Agriculture, Fisheries and Food in the United Kingdom in 1984. Today, myco-protein is produced in two 150,000 l pressure-cycle fermenters in a continuous process which outputs around 300 kg biomass/h. The continuous process is typically operated for around 1,000 h. One factor which has limited the length of production runs was the appearance of highly branched mutants in the population. Several factors affect the time of appearance of such mutants and a number of strategies for delaying their appearance have been investigated. After reduction of the RNA content, the fungal biomass is mixed with egg albumin and made into a variety of products. Consumption of these can lead to reduced blood cholesterol and to lower energy intake in a subsequent meal. E venenatum myco-protein is now used in products available in six European countries and there are plans for it to be sold in France, the United States and Germany.

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References 39 · Cited by 242

Authors
Wiebe, M.
Affiliations
Aalborg University (DK)
Corresponding author
Wiebe, M.
Venue
Applied Microbiology and Biotechnology
Published
2002-03-01
Volume
58
Issue
4
Pages
421-427
ISSN
  • 0175-7598 (ISSN-L)
  • 1432-0614
OpenAlex
W2045578397
Cited by
242
References
39
Citations by year
2026: 28 · 2025: 30 · 2024: 29 · 2023: 19 · 2022: 28 · 2021: 34 · 2020: 22 · 2019: 5 · 2018: 4 · 2017: 6 · 2016: 8 · 2015: 2 · 2014: 2 · 2013: 4 · 2012: 3
FWCI
2.28
Type
journal article
Language
en
Open access
closed
Locations
  • Applied Microbiology and Biotechnology (publishedVersion)
  • PubMed (publishedVersion)
  • VBN Forskningsportal (Aalborg Universitet) (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Advanced Scientific Research Methods
  • Health Sciences › Medicine › Pharmacology › Fungal Biology and Applications
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Enzyme Production and Characterization
Keywords
Fusarium venenatum, continuous fermentation, ovalbumin, cholesterol lowering, energy intake
MeSH terms
Dietary Proteins, Fermentation, Food Handling, Fungal Proteins, Fusarium, Humans, Nutrition Assessment, Biomass

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