Cited by 73Medical Imaging Techniques and ApplicationsOptical Imaging and Spectroscopy TechniquesAnatomy and Medical Technology

How molecular imaging will enable robotic precision surgery: The role of artificial intelligence, augmented reality, and navigation

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Wendler, Thomas, van Leeuwen, Fijs W. B., Navab, Nassir, van Oosterom, Matthias N.·2021·European Journal of Nuclear Medicine and Molecular Imaging

Abstract

Molecular imaging is one of the pillars of precision surgery. Its applications range from early diagnostics to therapy planning, execution, and the accurate assessment of outcomes. In particular, molecular imaging solutions are in high demand in minimally invasive surgical strategies, such as the substantially increasing field of robotic surgery. This review aims at connecting the molecular imaging and nuclear medicine community to the rapidly expanding armory of surgical medical devices. Such devices entail technologies ranging from artificial intelligence and computer-aided visualization technologies (software) to innovative molecular imaging modalities and surgical navigation (hardware). We discuss technologies based on their role at different steps of the surgical workflow, i.e., from surgical decision and planning, over to target localization and excision guidance, all the way to (back table) surgical verification. This provides a glimpse of how innovations from the technology fields can realize an exciting future for the molecular imaging and surgery communities.

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  • Many other domains of medicine beyond transplantation could benefit from AI, including precision medicine, AI-assisted computer vision, augmented and virtual reality, and AI-assisted integration and collection of patients' records.

    “Moreover, while this manuscript focuses on the use of AI in transplantation, many other domains could benefit from it.”

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References 227 · Cited by 73

Research works printed but not linked: 4

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Authors
Wendler, T., van Leeuwen, F. W. B., Navab, N., & van Oosterom, M. N.
Affiliations
  • Technical University of Munich (DE)
  • Johns Hopkins University (US)
Corresponding author
Wendler, Thomas
Venue
European Journal of Nuclear Medicine and Molecular Imaging
Published
2021-06-29
Volume
48
Issue
13
Pages
4201-4224
ISSN
  • 1619-7070 (ISSN-L)
  • 1619-7089
OpenAlex
W3176675455
Cited by
73
References
227
Citations by year
2026: 13 · 2025: 10 · 2024: 20 · 2023: 14 · 2022: 13 · 2021: 3
FWCI
2.04
Type
journal article
Language
en
Open access
Locations
  • European Journal of Nuclear Medicine and Molecular Imaging (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion, cc-by)
  • Leiden Repository (Leiden University) (submittedVersion, cc-by)
  • Informationszentrum Lebenswissenschaften (ZB MED) (submittedVersion, cc-by)
  • mediaTUM (Technical University of Munich) (submittedVersion, other-oa)
  • OPUS (Augsburg University) (submittedVersion, cc-by)
Funders
Technische Universität München
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Medical Imaging Techniques and Applications
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
  • Physical Sciences › Engineering › Biomedical Engineering › Anatomy and Medical Technology
Keywords
molecular imaging, robotic surgery, precision surgery, minimally invasive surgery, surgical navigation, computer-aided visualization, artificial intelligence in surgery, surgical planning, target localization, surgical verification
MeSH terms
Augmented Reality, Artificial Intelligence, Humans, Surgery, Computer-Assisted, Molecular Imaging, Robotic Surgical Procedures

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