Clinical Outcomes and Complications Associated with Fractional Lasers: A Review of 730 Patients
Abstract
Background Fractional lasers were introduced to provide increased safety, while maintaining high efficacy and patient satisfaction. Patients with virtually all Fitzpatrick skin types could be safely treated using a wide spectrum of wavelengths and a broad array of skin conditions, and aging could be addressed. Although safety studies have been reported for ablative CO 2 and erbium lasers, surprisingly few data are available on adverse events and complications associated with fractional lasers. Objective We report the frequency of adverse events, skin improvement and complications in a broad range of skin types using a standardized protocol that can be safely tailored to the patient's presenting complaints by varying the laser wavelength and number of treatments. Materials and methods The medical records of 730 patients (>90% females, age ranged from 50.5. to 59.9 years.) who had been treated at FACES+ Aesthetic Facility were reviewed. Patients were followed from 1 to 10 months and were reviewed to determine the frequency of complications, as well as their frequency, type, cause, treatment and resolution thereof. Patients were categorized by Fitzpatrick skin type (I-IV) to determine whether skin type was related to the frequency of complications. Improvement in skin condition (wrinkles, nasolabial folds and pigment) was rated by a technician before and after treatment using a Likert scale, 0-5, with 0 being no change and 5 being the most improvement. Results Seven hundred thir…
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Fraxel laser treatment showed significant improvements in both pigmentation and wrinkles from baseline, with an overall low risk of adverse events.
“In a retrospective study reviewing 730 patients with diverse skin types and ethnic backgrounds, Fraxel laser treatment showed significant improvements in both pigmentation and wrinkles from baseline, with an overall low risk of adverse events [5]”
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Qin, X., Zhai, J., Zhou, C., Wang, Y., Chen, M., Zhu, L., Shi, Q., Chen, W., Zhang, L., Luo, X., et al. (2025) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.70251 · Cited by 3 · see citing works
- Authors
- Cohen, S. R., Goodacre, A., Lim, S., Johnston, J., Henssler, C., Jeffers, B., Saad, A., & Leong, T.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Cohen, Steven R.
- Venue
- Aesthetic Plastic Surgery
- Published
- 2016-12-28
- Volume
- 41
- Issue
- 1
- Pages
- 171-178
- ISSN
- 0364-216X (ISSN-L)
- 1432-5241
- OpenAlex
- W2566868499
- Cited by
- 42
- References
- 0
- Citations by year
- 2026: 1 · 2025: 7 · 2024: 3 · 2023: 2 · 2022: 4 · 2021: 5 · 2020: 5 · 2019: 9 · 2018: 4 · 2017: 2
- FWCI
- 6.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Aesthetic Plastic Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
- Health Sciences › Medicine › Dermatology › Facial Rejuvenation and Surgery Techniques
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Laser Applications in Dentistry and Medicine
- Keywords
- fractional laser, laser complications, adverse events, Fitzpatrick skin type, skin aging, wrinkles, nasolabial fold, skin pigmentation, laser wavelength, treatment outcomes, downtime, patient satisfaction, cosmetic dermatology, laser safety, laser efficacy
- MeSH terms
- Cosmetic Techniques, Edema, Erythema, Esthetics, Female, Humans, Male, Retrospective Studies, Skin Aging, Databases, Factual, Treatment Outcome, Patient Satisfaction, Hyperpigmentation, Risk Assessment, Patient Selection, Low-Level Light Therapy, Lasers, Solid-State, Lasers, Gas
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