Cited by 164Thyroid and Parathyroid SurgeryThyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Total Thyroidectomy for Benign Thyroid Disorders in an Endemic Region

Mishra, Anjali, Agarwal, Amit, Agarwal, Gaurav, Mishra, S.K.·2001·World Journal of Surgery

Abstract

Abstract.: Total thyroidectomy is increasingly being accepted as a treatment of choice for differentiated thyroid cancer. However, because of presumed increased morbidity associated with this procedure, it is still not considered a viable option for management of benign thyroid disorders. To assess the safety and efficacy of total thyroidectomy for management of benign thyroid disorders, we analyzed our data from 127 total thyroidectomies performed for benign thyroid disorders. Demographic details, biochemical findings, indications for operation, specimen weight, and complications were noted. Among these patients, 52 had a toxic goiter and 75 had a nontoxic goiter. The mean duration of the goiters being present was 6.08 ± 6.06 years (0.9–26.0 years), and the mean weight of the specimens was 136.88 ± 120.68 g. The incidence of occult malignancy was 6.3% (n= 8), and those of permanent hypothyroidism and permanent recurrent laryngeal nerve palsy were 1.6% and 0.8%, respectively. Total thyroidectomy should be considered a treatment of choice for multinodular goiter and Graves' disease in a setting of palpable nodule(s) or ophthalmopathy (or both). It is particularly relevant in endemic regions where patients present with a long‐standing, large nodular goiter with virtually no normal thyroid tissue. Reoperation for recurrent goiter in such a setting would be fraught with distressing complications.

Integrity signals

Registry

Crossref · 10.1007/s002680020100

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The citation lists haven’t been fetched yet

References 22 · Cited by 164

Authors
Mishra, A., Agarwal, A., Agarwal, G., & Mishra, S. K.
Affiliations
Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN)
Venue
World Journal of Surgery
Publisher
Wiley
Published
2001-03
Volume
25
Issue
3
Pages
307-310
ISSN
  • 0364-2313 (ISSN-L)
  • 1432-2323
OpenAlex
W2081040407
Cited by
164
References
22
Citations by year
2026: 1 · 2025: 1 · 2024: 6 · 2023: 9 · 2022: 3 · 2021: 2 · 2020: 5 · 2019: 4 · 2018: 2 · 2017: 6 · 2016: 7 · 2015: 6 · 2014: 4 · 2013: 4 · 2012: 15
FWCI
7.59
Type
journal article
Language
en
Open access
closed
Locations
  • World Journal of Surgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
Keywords
total thyroidectomy, multinodular goiter, Graves' disease, toxic goiter, nontoxic goiter, permanent hypothyroidism, recurrent laryngeal nerve palsy, postoperative complications, endemic goiter
MeSH terms
Adult, Female, Goiter, Goiter, Endemic, Goiter, Nodular, Graves Disease, Humans, Male, Middle Aged, Thyroidectomy

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review