Total Thyroidectomy for Benign Thyroid Disorders in an Endemic Region
Abstract
Abstract.: Total thyroidectomy is increasingly being accepted as a treatment of choice for differentiated thyroid cancer. However, because of presumed increased morbidity associated with this procedure, it is still not considered a viable option for management of benign thyroid disorders. To assess the safety and efficacy of total thyroidectomy for management of benign thyroid disorders, we analyzed our data from 127 total thyroidectomies performed for benign thyroid disorders. Demographic details, biochemical findings, indications for operation, specimen weight, and complications were noted. Among these patients, 52 had a toxic goiter and 75 had a nontoxic goiter. The mean duration of the goiters being present was 6.08 ± 6.06 years (0.9–26.0 years), and the mean weight of the specimens was 136.88 ± 120.68 g. The incidence of occult malignancy was 6.3% (n= 8), and those of permanent hypothyroidism and permanent recurrent laryngeal nerve palsy were 1.6% and 0.8%, respectively. Total thyroidectomy should be considered a treatment of choice for multinodular goiter and Graves' disease in a setting of palpable nodule(s) or ophthalmopathy (or both). It is particularly relevant in endemic regions where patients present with a long‐standing, large nodular goiter with virtually no normal thyroid tissue. Reoperation for recurrent goiter in such a setting would be fraught with distressing complications.
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Near-total or total thyroidectomy can be performed with the same low rate of complications as subtotal thyroidectomy.
“This procedure can be performed with the same low rate of complications as a subtotal thyroidectomy (286-289).”
From 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis (2016) · cites this paper as [287]
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References 22 · Cited by 164
- Authors
- Mishra, A., Agarwal, A., Agarwal, G., & Mishra, S. K.
- Affiliations
- Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN)
- Venue
- World Journal of Surgery
- Publisher
- Wiley
- Published
- 2001-03
- Volume
- 25
- Issue
- 3
- Pages
- 307-310
- ISSN
- 0364-2313 (ISSN-L)
- 1432-2323
- OpenAlex
- W2081040407
- Cited by
- 164
- References
- 22
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 6 · 2023: 9 · 2022: 3 · 2021: 2 · 2020: 5 · 2019: 4 · 2018: 2 · 2017: 6 · 2016: 7 · 2015: 6 · 2014: 4 · 2013: 4 · 2012: 15
- FWCI
- 7.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- World Journal of Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Keywords
- total thyroidectomy, multinodular goiter, Graves' disease, toxic goiter, nontoxic goiter, permanent hypothyroidism, recurrent laryngeal nerve palsy, postoperative complications, endemic goiter
- MeSH terms
- Adult, Female, Goiter, Goiter, Endemic, Goiter, Nodular, Graves Disease, Humans, Male, Middle Aged, Thyroidectomy
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