The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Imaging oxygenation of human tumours
Open accessAbstract
Tumour hypoxia represents a significant challenge to the curability of human tumours leading to treatment resistance and enhanced tumour progression. Tumour hypoxia can be detected by non-invasive and invasive techniques but the inter-relationships between these remains largely undefined. (18)F-MISO and Cu-ATSM-PET, and BOLD-MRI are the lead contenders for human application based on their non-invasive nature, ease of use and robustness, measurement of hypoxia status, validity, ability to demonstrate heterogeneity and general availability, these techniques are the primary focus of this review. We discuss where developments are required for hypoxia imaging to become clinically useful and explore potential new uses for hypoxia imaging techniques including biological conformal radiotherapy.
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Citations
Cites
Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects
Hockel, M., & Vaupel, P. (2001) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/93.4.266 · Cited by 2,662 · cited 1×
“With these caveats in mind, the critical pO2 tensions below which cellular functions progressively cease or anticancer treatments are impaired are approximately as follows [13]: Effectiveness of immunotherapy becomes impaired (30–35 mmHg); Photodynamic therapy (15–35 mmHg); Cell death on exposure to radiation (25– 30…”
BackgroundGray, L. H., Conger, A. D., Ebert, M., Hornsey, S., & Scott, O. C. A. (1953) · The British Journal of Radiology · doi:10.1259/0007-1285-26-312-638 · Cited by 2,158
Cited by
Hypoxia in cancer: significance and impact on clinical outcome
Vaupel, P., & Mayer, A. (2007) · Cancer and Metastasis Reviews · doi:10.1007/s10555-007-9055-1 · Cited by 2,240
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
Dewhirst, M. W., Cao, Y., & Moeller, B. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2397 · Cited by 1,022
Ultrasensitive Near-Infrared Fluorescence-Enhanced Probe for in Vivo Nitroreductase Imaging
Li, Y., Sun, Y., Li, J., Su, Q., Yuan, W., Dai, Y., Han, C., Wang, Q., Feng, W., & Li, F. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b04097 · Cited by 516
Krohn, K. A., Link, J. M., & Mason, R. P. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.107.045914 · Cited by 506
Self-citationZhang, S., Hosaka, M., Yoshihara, T., Negishi, K., Iida, Y., Tobita, S., & Takeuchi, T. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-3948 · Cited by 349
Metadata
- Authors
- Padhani, A. R., Krohn, K. A., Lewis, J. S., & Alber, M.
- Venue
- European Radiology
- Published
- 2006-10-17
- Volume
- 17
- Issue
- 4
- Pages
- 861-872
- ISSN
- 0938-7994 (ISSN-L)
- 1432-1084
- OpenAlex
- W2094146747
- Cited by
- 328
- References
- 2
- FWCI
- 6.64
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Padhani, A. R., Krohn, K. A., Lewis, J. S., & Alber, M. (2007). Imaging oxygenation of human tumours. European Radiology. https://doi.org/10.1007/s00330-006-0431-y
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