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Cited by 19Corneal surgery and disordersCorneal Surgery and TreatmentsOcular and Laser Science Research

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

Comparison of different excimer laser ablation frequencies (50, 200, and 500 Hz)

Winkler von Mohrenfels, C., Khoramnia, R., Lohmann, C.-P.·2009·Graefe's Archive for Clinical and Experimental Ophthalmology
DOI 10.1007/s00417-009-1102-x
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Abstract

Purpose The aim of this study was to compare the influence of different excimer laser (193 nm) ablation frequencies (50, 200, and 500 Hz) on porcine cornea. Methods For this study, fresh porcine cadaver eyes were obtained from the butcher. PRK and LASIK were performed using a WaveLight Concept System 500 excimer laser. Various repetition rates (50, 200, and 500 Hz) and intended corrections (between -3 and -9 D) were used. Corneal endothelium was investigated pre- and post-operatively with the endothelial cell microscope EM 1000 Tomey. Post-operatively, the corneas were embedded for light microscopic (HE, Picrosirius Red) and electron microscopic evaluation. Results The mean pre-operative cell count was 2,953 (SD 149) and the mean post-operative cell count was 2,974 (SD 156). There was no difference between the pre- and post-operative cell count and the different ablation frequencies. The distribution of collagen fibers and keratocytes was comparable in all different ablation frequencies. Also, the ultrastructural evaluation of keratocytes and fibers, assessed with transmission electron microscopy, was equal in all three different ablation frequencies. Conclusions The endothelial cell density and structural and ultra structural evaluation of the different ablation frequencies (50, 200, 500 Hz) showed no specific side-effects that could be associated with higher repetition rates. The quality of the ablation was comparable in all three different laser ablation frequencies. The 5…

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Crossref · 10.1007/s00417-009-1102-x

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Metadata

Authors
Winkler von Mohrenfels, C., Khoramnia, R., & Lohmann, C.-P.
Affiliations
TUM Klinikum (DE)
ORCID
Khoramnia, R.
Venue
Graefe's Archive for Clinical and Experimental Ophthalmology
Publisher
Springer Science and Business Media LLC
Published
2009-07-14
Volume
247
Issue
11
Pages
1539-1545
ISSN
  • 0721-832X (ISSN-L)
  • 1435-702X
DOI
10.1007/s00417-009-1102-x
OpenAlex
W2030344747
Cited by
19
References
16
Citations by year
2026: 1 · 2024: 1 · 2023: 1 · 2021: 1 · 2020: 3 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 1 · 2013: 2
FWCI
0.75
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • Graefe s Archive for Clinical and Experimental Ophthalmology (publishedVersion)
  • PubMed (publishedVersion)
  • mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
Topics
  • Health Sciences › Medicine › Ophthalmology › Corneal surgery and disorders
  • Health Sciences › Medicine › Ophthalmology › Corneal Surgery and Treatments
  • Health Sciences › Medicine › Ophthalmology › Ocular and Laser Science Research
Keywords
repetition rate, 193 nm excimer laser, photorefractive keratectomy, LASIK, porcine cornea, corneal endothelium, endothelial cell density, keratocytes, corneal ultrastructure, refractive surgery
MeSH terms
Animals, Cell Count, Collagen, Cornea, Endothelium, Corneal, Fibroblasts, Microscopy, Electron, Scanning, Microscopy, Phase-Contrast, Swine, Photorefractive Keratectomy, Keratomileusis, Laser In Situ, Microscopy, Electron, Transmission, Lasers, Excimer

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