The DOI matches its Crossref record.
Changes in the elastic properties of tendon structures following 20 days bed-rest in humans
Abstract
The purpose of this study was to investigate the effects of 20 days bed-rest on the elastic properties of tendon structures of the human knee extensor muscles in vivo. Six healthy men carried out a 6 degrees head-down bed-rest for 20 days. Muscle volume and maximal voluntary contraction (MVC) torque of the quadriceps femoris muscle significantly decreased by an average of 7.8 (SD 2.7)% and 14.9 (SD 6.9)%, respectively. Before and after bed-rest, the elongation (l) of the tendon and aponeurosis of vastus lateralis muscle was measured directly by ultrasonography, while the subjects performed ramp isometric knee extension up to MVC. The extent of l tended to be greater after bed-rest. The l above 110 N was significantly greater after bed-rest. Furthermore, the mean stiffness after bed-rest [35.5 (SD 7.8) N x mm(-1)] was significantly lower than that before bed-rest [52.6 (SD 19.2) N x mm(-1)]. The rate of torque development significantly reduced after bed-rest by an average of 47%, and the bed-rest induced a lengthening in the electromechanical delay (mean 21%). These results suggest that bed-rest results in a decrease in the stiffness of tendon structures with a reduction of muscle strength and volume. These adaptations of the tendon structures to bed-rest would bring about the changes in electromechanical delay and rate of torque development.
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In the citing paper
“Numerically established degeneration rates for the knee extensors differed by 5% to 80% dependent on the duration of disuse (6, 18, 21–23).”
From Nonuniform loss of muscle strength and atrophy during bed rest: a systematic review (2021) · cites this paper as [6]
In the citing paper
“Prolonged periods of bed rest result in a significant atrophy of musculoskeletal mass and volume in the weight-bearing leg musculature such as the quadriceps femoris (5–8).”
From Nonuniform loss of muscle strength and atrophy during bed rest: a systematic review (2021) · cites this paper as [6]
In the citing paper
“Our systematic review is in general agreement with the majority of other bed rest trials, which report that muscle strength is compromised to a greater extent than muscle size following bed rest (6, 7, 10, 18, 19, 21–23, 56, 58).”
From Nonuniform loss of muscle strength and atrophy during bed rest: a systematic review (2021) · cites this paper as [6]
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Items 101–113 of 113
Koryak Yuri, A. (2017) · International Journal of Sports and Exercise Medicine · doi:10.23937/2469-5718/1510080
Koryak, Y. A. (2021) · Japan Journal of Research · doi:10.33425/2690-8077.1034
Pereira, C. S., Klauznicer, J., Maree, D., Auliffe, S. M., Farooq, A., Whiteley, R. J., & Finni, T. J. (2023) · Frontiers in Rehabilitation Sciences · doi:10.3389/fresc.2023.1283635
Koryak, Y. A., Kukoba, T. B., & Babich, D. R. (2023) · Human Physiology · doi:10.31857/s0131164622600604
Koryak, Y. A. (2024) · Endocrinology&Metabolism International Journal · doi:10.15406/emij.2024.12.00357
Burakgazi, G., ÖZ, F., & Aslan, A. (2025) · Journal of the American Podiatric Medical Association · doi:10.7547/22-215
Lowe, T. W., Suresh, T., Oro, E. G., Freedberg, M., Hussain, S. J., & Griffin, L. (2025) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000003872
The role of muscle tendon unit elasticity in real life activities.
Lichtwark, G. A. (2005) · OpenGrey (Institut de l'Information Scientifique et Technique)
Ta, G., Li, L., Jing, C., Chen, X., Jeong, S.-J., Ryu, D., & Wei, S. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1935289
The Effects of Instrument-Assisted Cross Fiber Massage on Ligament Healing
Loghmani, M. T. (2010) · IUScholarWorks (Indiana University) · doi:10.7912/c2/2091
Metadata
- Authors
- Kubo, K., Akima, H., Kouzaki, M., Ito, M., Kawakami, Y., Kanehisa, H., & Fukunaga, T.
- Affiliations
- The University of Tokyo (JP)
- Venue
- European Journal of Applied Physiology
- Published
- 2000-12-13
- Volume
- 83
- Issue
- 6
- Pages
- 463-468
- ISSN
- 0020-9376 (ISSN-L)
- 1439-6319
- 1439-6327
- OpenAlex
- W2019082585
- Cited by
- 113
- References
- 0
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 2 · 2023: 5 · 2022: 4 · 2021: 4 · 2020: 2 · 2019: 3 · 2018: 3 · 2017: 8 · 2016: 4 · 2015: 7 · 2014: 5 · 2013: 4 · 2012: 2
- FWCI
- 1.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- European Journal of Applied Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Spaceflight effects on biology
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Tendon Structure and Treatment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Keywords
- bed rest, tendon stiffness, quadriceps, vastus lateralis, muscle atrophy, electromechanical delay, rate of torque development, head-down bed rest, muscle strength
- MeSH terms
- Adult, Bed Rest, Elasticity, Electromyography, Humans, Isometric Contraction, Knee, Male, Tendons, Time Factors, Ultrasonography, Muscle, Skeletal, Torque
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