A cross-sectional analysis of otitis media with effusion in children with Down syndrome
Abstract
Unlabelled Children with Down syndrome are at risk to develop otitis media with effusion (OME). We performed a retrospective and cross-sectional analysis to evaluate the prevalence of OME in children with Down syndrome (DS) for consecutive age categories between 6 months and 12 years. Clinical and audiometric data were available for 107 children followed in a multidisciplinary Down team. A high prevalence of OME was found at the age of 1 year (66.7 %), with a second peak prevalence of 60 % at 6-7 years. A declining trend was observed in children ≥8 years. Overall, 52.3 % of DS children had either OME or ventilation tubes at the time of evaluation. Hearing thresholds were significantly higher in children with bilateral OME (median 36.7 decibel hearing level (dB HL), range 26.7-46.1) compared to those with at least one normally ventilated middle ear (median 28.3 dB HL, range 22.8-3.3), p = 0.013. Conclusion We found a high prevalence of OME in children with Down syndrome, with a peak of ≥60 % around 1 and 6-7 years. A declining trend is seen in older children. Mild to moderate hearing loss was present in children with bilateral OME.
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OME is more prevalent in children with Down syndrome or cleft palate.
“The condition is more prevalent in children with Down syndrome or cle palate (Flynn 2009;Maris 2014).”
From Topical and oral steroids for otitis media with effusion (OME) in children (2023) · cites this paper as Maris 2014
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References 18 · Cited by 69
- Authors
- Maris, M., Wojciechowski, M., Van de Heyning, P., & Boudewyns, A.
- Affiliations
- University of Antwerp (BE)
- Corresponding author
- Boudewyns, An
- Venue
- European Journal of Pediatrics
- Published
- 2014-05-10
- Volume
- 173
- Issue
- 10
- Pages
- 1319-1325
- ISSN
- 0340-6199 (ISSN-L)
- 1432-1076
- OpenAlex
- W2072834728
- Cited by
- 69
- References
- 18
- Citations by year
- 2025: 4 · 2024: 8 · 2023: 11 · 2022: 11 · 2021: 5 · 2020: 8 · 2019: 10 · 2018: 3 · 2017: 5 · 2016: 3 · 2015: 1
- FWCI
- 2.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- European Journal of Pediatrics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Otorhinolaryngology › Ear Surgery and Otitis Media
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Down syndrome and intellectual disability research
- Health Sciences › Medicine › Oncology › Ear and Head Tumors
- Keywords
- otitis media with effusion, Down syndrome, prevalence, hearing loss, tympanostomy tubes, middle ear, children, age trends
- MeSH terms
- Belgium, Child, Child, Preschool, Cross-Sectional Studies, Down Syndrome, Female, Hearing Loss, Conductive, Humans, Infant, Male, Otitis Media with Effusion, Retrospective Studies, Prevalence, Age Distribution
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