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Anticipatory nausea and vomiting

Roscoe, Joseph A., Morrow, Gary R., Aapro, Matti S., Molassiotis, Alexander, Olver, Ian·2011·Supportive Care in Cancer

Abstract

A commonly reported consequence of post-treatment nausea or vomiting is the development of anticipatory nausea and vomiting (ANV). In most published work, nausea is reported to occur before chemotherapy drugs are administered by approximately 20% of patients at any one chemotherapy cycle and by 25–30% of patients by their fourth chemotherapy cycle. Most studies in adult patients strongly support the view that the development of ANV involves elements of classical conditioning. The best method to avoid development of ANV is to adequately prevent both vomiting and nausea from the first exposure to chemotherapy. If anticipatory side effects develop, behavioral treatment techniques, such as systematic desensitization, have been shown effective. Benzodiazepines used in combination with behavioral techniques or antiemetics may also be useful. The evidence on which these conclusions are based is reviewed in this article.

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Metadata

Authors
Roscoe, J. A., Morrow, G. R., Aapro, M. S., Molassiotis, A., & Olver, I.
Venue
Supportive Care in Cancer
Published
2010-08-30
Volume
19
Issue
10
Pages
1533-1538
ISSN
  • 0941-4355 (ISSN-L)
  • 1433-7339
OpenAlex
W4232736732
Cited by
161
References
2
FWCI
8.07
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Anticipatory nausea and vomiting. https://app.cochat.ai/papers/10.1007/s00520-010-0980-0
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Roscoe, J. A., Morrow, G. R., Aapro, M. S., Molassiotis, A., & Olver, I. (2011). Anticipatory nausea and vomiting. Supportive Care in Cancer. https://doi.org/10.1007/s00520-010-0980-0

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