The DOI matches its Crossref record; 21 of the 22 references it cites were found in a registry or an index.
Review of the pathological results of 2660 appendicectomy specimens
Abstract
Purpose Appendicitis is the most commonly performed emergency abdominal surgery. The appendix can also be the site of a variety of neoplasms and unusual inflammatory conditions. A retrospective review was performed to determine the pathological diagnoses in appendicectomy specimens. Methods This study is a retrospective analysis of 2660 appendicectomies performed from 1997 to 2003. The reports were analyzed for the following parameters: age-related incidence of acute appendicitis, seasonal variation in presentation, perforation rate, rate of negative and incidental appendicectomy, and the incidence of other pathologies encountered. Results Of the 2660 appendicectomy specimens, acute appendicitis was seen in 1718 patients (64.58%), with a peak in patients in their second decade (35.09% of cases of acute appendicitis). The perforation rate was 13.9% and was significantly higher in patients aged 70 years or more (P Conclusions The high rate of negative appendicectomy among female patients and the increased incidence of perforation in elderly patients reinforce the validity of the judicious use of laparoscopy in these populations. There are still a number of unusual histologies found in appendicectomy specimens supporting the continued use of routine histology.
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“This phenomenon, often referred to as a “negative appendectomy,” has been reported in 10% to 20% of cases, and up to 30% in specific populations such as young women and children [33,34].”
From Selective Appendectomy in Patients Undergoing Minimally Invasive Surgery for Endometriosis: A Retrospective Cohort Study (2025) · cites this paper as [34]
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Cited by
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Appendiceal neoplasms and pseudomyxoma peritonei: A population based study
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Diverticulosis and Diverticulitis of the Appendix
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Metadata
- Authors
- Marudanayagam, R., Williams, G. T., & Rees, B. I.
- Affiliations
- University Hospital of Wales (GB)
- ORCID
- Marudanayagam, Ravi
- Venue
- Journal of Gastroenterology
- Published
- 2006-09-19
- Volume
- 41
- Issue
- 8
- Pages
- 745-749
- ISSN
- 0944-1174 (ISSN-L)
- 1435-5922
- OpenAlex
- W1966647446
- Cited by
- 291
- References
- 22
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 17 · 2023: 10 · 2022: 27 · 2021: 15 · 2020: 21 · 2019: 19 · 2018: 22 · 2017: 17 · 2016: 19 · 2015: 7 · 2014: 23 · 2013: 15 · 2012: 16
- FWCI
- 9.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Emergency Medicine › Appendicitis Diagnosis and Management
- Health Sciences › Medicine › Surgery › Intraperitoneal and Appendiceal Malignancies
- Health Sciences › Medicine › Surgery › Omental and Epiploic Conditions
- Keywords
- appendicitis, appendectomy, pathological diagnosis, acute appendicitis, appendiceal perforation, appendiceal neoplasms, appendiceal carcinoid, appendiceal adenocarcinoma, mucinous cystadenoma, age-related incidence, seasonal variation, laparoscopic appendectomy
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Appendectomy, Appendicitis, Appendix, Child, Female, Humans, Male, Middle Aged, Laparoscopy, Retrospective Studies, Age Distribution
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