Cited by 37Plant Stress Responses and TolerancePlant nutrient uptake and metabolismATP Synthase and ATPases Research

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Congruence between PM H+-ATPase and NADPH oxidase during root growth: a necessary probability

Majumdar, Arkajo, Kar, Rup Kumar·2018·Protoplasma

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Abstract

Plasma membrane (PM) H+-ATPase and NADPH oxidase (NOX) are two key enzymes responsible for cell wall relaxation during elongation growth through apoplastic acidification and production of ˙OH radical via O 2˙-, respectively. Our experiments revealed a putative feed-forward loop between these enzymes in growing roots of Vigna radiata (L.) Wilczek seedlings. Thus, NOX activity was found to be dependent on proton gradient generated across PM by H+-ATPase as evident from pharmacological experiments using carbonyl cyanide m-chlorophenylhydrazone (CCCP; protonophore) and sodium ortho-vanadate (PM H+-ATPase inhibitor). Conversely, H+-ATPase activity retarded in response to different ROS scavengers [CuCl 2, N, N' -dimethylthiourea (DMTU) and catalase] and NOX inhibitors [ZnCl 2 and diphenyleneiodonium (DPI)], while H 2 O 2 promoted PM H+-ATPase activity at lower concentrations. Repressing effects of Ca+2 antagonists (La+3 and EGTA) on the activity of both the enzymes indicate its possible mediation. Since, unlike animal NOX, the plant versions do not possess proton channel activity, harmonized functioning of PM H+-ATPase and NOX appears to be justified. Plasma membrane NADPH oxidase and H+-ATPase are functionally synchronized and they work cooperatively to maintain the membrane electrical balance while mediating plant cell growth through wall relaxation.

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Authors: Majumdar, A., & Kar, R. K.
Affiliations: Visva-Bharati University (IN)
Corresponding author: Kar, Rup Kumar
ORCID: Majumdar, Arkajo
Kar, Rup Kumar
Venue: Protoplasma
Publisher: Springer Science and Business Media LLC
Published: 2018-02-12
Volume: 255
Issue: 4
Pages: 1129-1137
ISSN: 0033-183X (ISSN-L)
1615-6102
DOI: 10.1007/s00709-018-1217-1
OpenAlex: W2789128986
Cited by: 37
References: 58
Citations by year: 2025: 5 · 2024: 4 · 2023: 5 · 2022: 5 · 2021: 9 · 2020: 5 · 2019: 2 · 2018: 2
FWCI: 3.98
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: PROTOPLASMA (publishedVersion)
PubMed (publishedVersion)
Funders: University Grants Commission, New Delhi, India (F. No. 25-1/2014-15(BSR)/220/2009/(BSR))
Topics: Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant nutrient uptake and metabolism
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › ATP Synthase and ATPases Research
Keywords: plasma membrane H+-ATPase, NADPH oxidase, root elongation, feed-forward loop, reactive oxygen species, hydrogen peroxide, calcium signaling, mungbean, diphenyleneiodonium, sodium orthovanadate
MeSH terms: Cell Membrane, Proton-Translocating ATPases, Plant Roots, NADPH Oxidases

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Congruence between PM H+-ATPase and NADPH oxidase during root growth: a necessary probability

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