Are exposure-based cognitive behavioral therapies safe during pregnancy?
Abstract
Anxiety disorders during pregnancy are highly prevalent and associated with serious and enduring consequences for both mother and child. Exposure-based cognitive behavioral (CBT) and behavioral therapies (BT) represent the most empirically supported psychosocial treatments for anxiety disorders in general adult samples. Pregnant women, however, generally have been excluded from this body of research. Evidence that pregnant women inhabit a unique biological context combined with untested assumptions that exposure would unduly stress or harm the fetus have likely prohibited inquiry. This paper seeks to remedy this gap by integrating findings from obstetric, psychiatric, and psychological research to inform central questions regarding exposure-based treatment of anxiety disorders during pregnancy. Based on available evidence, we consider the potential risks and benefits of CBT/BT for anxiety disorders during pregnancy relative to other currently available treatment options. From a multidisciplinary research perspective, we argue that exposure-based therapies are likely to be safe during pregnancy, particularly relative to the alternatives. However, we also highlight critical questions for future research to directly test the biopsychological impact of exposure-based therapies among pregnant women.
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It is possible that researchers, clinicians, and regulatory boards are overestimating the risk that exposure therapy poses to pregnant women.
“Thus, it is possible that researchers, clinicians, and regulatory boards are overestimating the risk that exposure therapy poses to pregnant women.”
From Exposure Therapy Acceptability Among Pregnant Latinas With Anxiety: A Qualitative Content Analysis (2025) · cites this paper as Arch et al., 2012
To date, there are no direct tests of physiological stress responses to exposure therapy in pregnancy.
“To date, there are no direct tests of physiological stress responses to exposure therapy in pregnancy (Arch et al., 2012)”
From Exposure Therapy Acceptability Among Pregnant Latinas With Anxiety: A Qualitative Content Analysis (2025) · cites this paper as Arch et al., 2012
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References 111 · Cited by 71
- Authors
- Arch, J. J., Dimidjian, S., & Chessick, C.
- Affiliations
- University of Colorado Boulder (US)
- University of Colorado Anschutz (US)
- Corresponding author
- Arch, Joanna J.
- Dimidjian, Sona
- Chessick, Cheryl
- Venue
- Archives of Women's Mental Health
- Published
- 2012-09-16
- Volume
- 15
- Issue
- 6
- Pages
- 445-457
- ISSN
- 1434-1816 (ISSN-L)
- 1435-1102
- OpenAlex
- W2152903233
- Cited by
- 71
- References
- 111
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 4 · 2023: 5 · 2022: 6 · 2021: 8 · 2020: 6 · 2019: 2 · 2018: 2 · 2017: 8 · 2016: 6 · 2015: 5 · 2014: 4 · 2013: 4
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Archives of Women s Mental Health (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of Colorado Boulder
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- exposure-based cognitive behavioral therapy, pregnancy, anxiety disorders in pregnancy, treatment safety, behavior therapy, fetal stress, maternal mental health
- MeSH terms
- Anxiety Disorders, Female, Humans, Implosive Therapy, Pregnancy, Pregnancy Complications, Cognitive Behavioral Therapy, Evidence-Based Medicine
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