Cited by 212Maternal Mental Health During Pregnancy and PostpartumMaternal and Perinatal Health InterventionsMaternal and Neonatal Healthcare

The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.

Preventing postpartum depression: review and recommendations

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Abstract

Nearly 20 % of mothers will experience an episode of major or minor depression within the first 3 months postpartum, making it the most common complication of childbearing. Postpartum depression (PPD) is significantly undertreated, and because prospective mothers are especially motivated for self-care, a focus on the prevention of PPD holds promise of clinical efficacy. This study is a qualitative review of existing approaches to prevent PPD. A PubMed search identified studies of methods of PPD prevention. The search was limited to peer-reviewed, published, English-language, randomized controlled trials (RCTs) of biological, psychological, and psychosocial interventions. Eighty articles were initially identified, and 45 were found to meet inclusion criteria. Eight RCTs of biological interventions were identified and 37 RCTs of psychological or psychosocial interventions. Results were mixed, with 20 studies showing clear positive effects of an intervention and 25 showing no effect. Studies differed widely in screening, population, measurement, and intervention. Among biological studies, anti-depressants and nutrients provided the most evidence of successful intervention. Among psychological and psychosocial studies, 13/17 successful trials targeted an at-risk population, and 4/7 trials using interpersonal therapy demonstrated success of the intervention versus control, with a further two small studies showing trends toward statistical significance. Existing approaches to the prevention of PPD vary widely, and given the current literature, it is not possible to identify one approach that is superior to others. Interpersonal therapy trials and trials that targeted an at-risk population appear to hold the most promise for further study.

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Metadata

Authors
Werner, E., Miller, M., Osborne, L. M., Kuzava, S., & Monk, C.
Affiliations
  • Columbia University Irving Medical Center (US)
  • Johns Hopkins University (US)
Corresponding author
  • Werner, Elizabeth
  • Kuzava, Sierra
Venue
Archives of Women's Mental Health
Published
2014-11-25
Volume
18
Issue
1
Pages
41-60
ISSN
  • 1434-1816 (ISSN-L)
  • 1435-1102
OpenAlex
W2042783002
Cited by
212
References
94
Citations by year
2026: 7 · 2025: 20 · 2024: 27 · 2023: 27 · 2022: 21 · 2021: 26 · 2020: 17 · 2019: 24 · 2018: 18 · 2017: 12 · 2016: 7 · 2015: 6
FWCI
1.31
Type
journal article
Language
en
Open access
Locations
  • Archives of Women s Mental Health (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Mental Health (R21MH092665, T32MH015144)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
  • Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and Neonatal Healthcare
Keywords
postpartum depression, prevention, antidepressants, nutrients, interpersonal psychotherapy, vulnerable populations, psychological intervention, psychosocial interventions, biological interventions, screening, maternal mental health
MeSH terms
Female, Humans, Mothers, Psychotherapy, Social Support, Randomized Controlled Trials as Topic, Depression, Postpartum

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